Areas of Focus
- Alzheimer's Disease
- Genetic Susceptibility Mechanisms
- Multi-Omics Integration Analysis
Work Experience
- 2020-08~Present - Kunming Institute of Zoology, Chinese Academy of Sciences - Associate Researcher
- 2020-07~2020-08 - Kunming Institute of Zoology, Chinese Academy of Sciences - Assistant Researcher
- 2014-09~2020-07 - University of Chinese Academy of Sciences - PhD
- 2010-09~2014-06 - Nanjing University - Bachelor
Academic Background & Achievements
- 2014-09--2020-07 PhD: University of Chinese Academy of Sciences
- 2010-09--2014-06 Bachelor: Nanjing University
Publications
- Common and rare variants of EGF increase the genetic risk of Alzheimer's disease as revealed by targeted sequencing of growth factors in Han Chinese, Neurobiology of Aging, 2023
- Convergent transcriptomic and genomic evidence supporting a dysregulation of CXCL16 and CCL5 in Alzheimer's disease, Alzheimer's Research & Therapy, 2023
- Functional genomics identify causal variant underlying the protective CTSH locus for Alzheimer's disease, Neuropsychopharmacology, 2023
- Coexistence of multiple functional variants and genes underlies genetic risk locus 11p11.2 of Alzheimer's disease, Biological Psychiatry, 2023
- Exploring the Genetic Association of the ABAT Gene with Alzheimer's Disease, Molecular Neurobiology, 2021
- Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model, Autophagy, 2020
- Longitudinal transcriptome analyses show robust T cell immunity during recovery from COVID-19, Signal Transduction and Targeted Therapy, 2020
- Complement C7 is a novel risk gene for Alzheimer's disease in Han Chinese, National Science Review, 2019
- Genetic Analyses of Alzheimer's Disease in China: Achievements and Perspectives, ACS Chemical Neuroscience, 2019
- Missense Variants in HIF1A and LACC1 Contribute to Leprosy Risk in Han Chinese, The American Journal of Human Genetics, 2018
- Genetic association of the cytochrome c oxidase-related genes with Alzheimer's disease in Han Chinese, Neuropsychopharmacology, 2018
- A systematic integrated analysis of brain expression profiles reveals yap1 and other prioritized hub genes as important upstream regulators in Alzheimer's disease, Alzheimer's and Dementia, 2018
- The GWAS Risk Genes for Depression May Be Actively Involved in Alzheimer's Disease, Journal of Alzheimer's Disease, 2018
- Missense Variants in HIF1A and LACC1 Contribute to Leprosy Risk in Han Chinese, American Journal of Human Genetics, 2018
- Rare Genetic Variants of the Transthyretin Gene Are Associated with Alzheimer's Disease in Han Chinese, Molecular Neurobiology, 2017