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徐敏
Life Science
中国科学院大学
云南
Language: 中文, 英语
阿尔茨海默病
遗传学
易感性
机制
多组学
整合
分析
神经生物学
基因组学
转录组学
Areas of Focus
- 阿尔茨海默病
- 遗传易感机制
- 多组学整合分析
Work Experience
- 2020-08~现在 - 中国科学院昆明动物研究所 - 副研究员
- 2020-07~2020-08 - 中国科学院昆明动物研究所 - 助理研究员
- 2014-09~2020-07 - 中国科学院大学 - 博士
- 2010-09~2014-06 - 南京大学 - 学士
Academic Background & Achievements
- 2014-09--2020-07 博士: 中国科学院大学
- 2010-09--2014-06 学士: 南京大学
Publications
- Common and rare variants of EGF increase the genetic risk of Alzheimer's disease as revealed by targeted sequencing of growth factors in Han Chinese, Neurobiology of Aging, 2023
- Convergent transcriptomic and genomic evidence supporting a dysregulation of CXCL16 and CCL5 in Alzheimer's disease, Alzheimer's Research & Therapy, 2023
- Functional genomics identify causal variant underlying the protective CTSH locus for Alzheimer's disease, Neuropsychopharmacology, 2023
- Coexistence of multiple functional variants and genes underlies genetic risk locus 11p11.2 of Alzheimer's disease, Biological Psychiatry, 2023
- Exploring the Genetic Association of the ABAT Gene with Alzheimer's Disease, Molecular Neurobiology, 2021
- Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model, Autophagy, 2020
- Longitudinal transcriptome analyses show robust T cell immunity during recovery from COVID-19, Signal Transduction and Targeted Therapy, 2020
- Complement C7 is a novel risk gene for Alzheimer's disease in Han Chinese, National Science Review, 2019
- Genetic Analyses of Alzheimer's Disease in China: Achievements and Perspectives, ACS Chemical Neuroscience, 2019
- Missense Variants in HIF1A and LACC1 Contribute to Leprosy Risk in Han Chinese, The American Journal of Human Genetics, 2018
- Genetic association of the cytochrome c oxidase-related genes with Alzheimer's disease in Han Chinese, Neuropsychopharmacology, 2018
- A systematic integrated analysis of brain expression profiles reveals yap1 and other prioritized hub genes as important upstream regulators in Alzheimer's disease, Alzheimer's and Dementia, 2018
- The GWAS Risk Genes for Depression May Be Actively Involved in Alzheimer's Disease, Journal of Alzheimer's Disease, 2018
- Missense Variants in HIF1A and LACC1 Contribute to Leprosy Risk in Han Chinese, American Journal of Human Genetics, 2018
- Rare Genetic Variants of the Transthyretin Gene Are Associated with Alzheimer's Disease in Han Chinese, Molecular Neurobiology, 2017
