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Tao Ye
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English
Alzheimer'S Disease
Genetic Factors
Ipsc
Disease Models
Genetic Risk Factors
Gene Editing
Gene Therapy
Crispr/Cas9
Neurodegenerative Diseases
Personalized Medicine
Areas of Focus
- Alzheimer's Disease (AD) - Genetic factors, iPSC disease models, genetic risk factors, gene editing, gene therapy
Work Experience
- 2020-04 to Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher
- 2018-09 to 2020-04 - Hong Kong University of Science and Technology - Research Assistant Professor
- 2014-02 to 2018-08 - Hong Kong University of Science and Technology - Postdoctoral Fellow
Academic Background & Achievements
- 2009-09 to 2014-01 PhD: Hong Kong University of Science and Technology
- 2005-09 to 2009-06 BSc: Wuhan University
Publications
- Generation of a homozygous ABCA7-knockout human iPSC line using the CRISPR/Cas9 system, Guan M, Chai Y, Yi R, Chen Y, Ip JPK, Ye T, Chen Y, 2023
- Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer's disease alleviates amyloid-related pathologies in mice, Duan Y, Ye T, Qu Z, Chen Y, Miranda A, Zhou X, Lok KC, Chen Y, Fu AKY, Gradinaru V, Ip NY, 2022
- Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases, Ye T, Duan Y, Tsang HWS, Xu H, Chen Y, Cao H, Chen Y, Fu AKY, Ip NY, 2021
- Emerging roles of Axin in cerebral cortical development, Ye T, Fu AKY, Ip NY, 2015
- Cdk5 Regulates Activity-Dependent Gene Expression and Dendrite Development, Liang Z, Ye T, Zhou X, Lai K-O, Fu AKY, Ip NY, 2015
- Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex, Ye T, Ip JPK, Fu AKY, Ip NY, 2014
- Cdk5-dependent Mst3 phosphorylation and activity regulate neuronal migration through RhoA inhibition, Tang J, Ip JPK, Ye T, Ng Y-P, Yung W-H, Wu Z, Fang W, Fu AKY, Ip NY, 2014
- Cyclin-dependent kinase 5 in axon growth and regeneration, Ye T, Fu AKY, Ip NY, 2012
- Ankyrin repeat-rich membrane spanning protein (kidins220) is required for neurotrophin and ephrin receptor-dependent dendrite development, Chen Y, Fu W-Y, Ip JPK, Ye T, Fu AKY, Chao MV, Ip NY, 2012
- Molecular and biochemical characterization of a distinct tyrosinase involved in melanin production from Aeromonas media, Wan X, Chai B, Liao Y, Su Y, Ye T, Shen P, Chen X, 2009
Awards
- Chinese Neuroscience Society (2021): Major Progress in Chinese Neuroscience
