2010-09 to 2013-06: Ph.D. from Wuhan Institute of Virology, Chinese Academy of Sciences
2007-09 to 2010-06: Master's from Huazhong Agricultural University
2003-09 to 2007-06: Bachelor's from Wuhan Polytechnic University
2021-10 to Present: Researcher at Wuhan Institute of Virology, Chinese Academy of Sciences
2018-04 to 2019-04: Visiting Scholar at University of Maryland, College Park
2018-01 to 2021-10: Young Researcher at Wuhan Institute of Virology, Chinese Academy of Sciences
2015-08 to 2017-12: Associate Researcher at Wuhan Institute of Virology, Chinese Academy of Sciences
2013-07 to 2015-08: Assistant Researcher at Wuhan Institute of Virology, Chinese Academy of Sciences
Wuhan Youth Science and Technology Morning Light Program (2016)
Wuhan Yellow Crane Talent (Science and Technology) Program (2016)
Third Prize at the Fourth Youth Scientist Forum of the Institute of Hydrobiology, Chinese Academy of Sciences (2013)
Hubei Province Excellent Master's Thesis (2012)
Paul Biotechnology Award for Outstanding Student (2012)
Research
Antimicrobial resistance and therapy Bacteriophage and host immunity Bacteriophage vector vaccines
Chrysin 7-O-β-D-glucuronide, a dual inhibitor of SARS-CoV-2 3CLpro and PLpro, for the prevention and treatment of COVID-19, Hang Yang, 2024
Calcium-binding motif-mediated binding of redundant calcium offers a chimeolysin enhanced bactericidal activity and extended host range under physiological conditions, Hang Yang, 2023
A pan-coronavirus peptide inhibitor prevents SARS-CoV-2 infection in mice by intranasal delivery, Hang Yang, 2023
Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV-2, Hang Yang, 2022
Effects of simeprevir on the replication of SARS-CoV-2 in vitro and in transgenic hACE2 mice, Hang Yang, 2022
Natural triterpenoids from licorice potently inhibit SARS-CoV-2 infection, Hang Yang, 2022
Schaftoside inhibits 3CL^(pro)and PL^(pro)of SARS-CoV-2 virus and regulates immune response and inflammation of host cells for the treatment of COVID-19, Hang Yang, 2022
Enriched Opportunistic Pathogens Revealed by Metagenomic Sequencing Hint Potential Linkages between Pharyngeal Microbiota and COVID-19, Hang Yang, 2021
A Novel Acinetobacter baumannii Bacteriophage Endolysin LysAB54 With High Antibacterial Activity Against Multiple Gram-Negative Microbes, Hang Yang, 2021
Internal cell-penetrating peptide-mediated internalization enables a chimeric lysin to target intracellular pathogens, Hang Yang, 2021
Intrinsic Antimicrobial Peptide Facilitates a New Broad-Spectrum Lysin LysP53 to Kill Acinetobacter baumannii In Vitro and in a Mouse Burn Infection Model, Hang Yang, 2021
Encapsulation and Delivery of Therapeutic Phages, Hang Yang, 2021
Genetic Polymorphism Drives Susceptibility Between Bacteria and Bacteriophages, Hang Yang, 2021
A Highly Active Chimeric Lysin with a Calcium-Enhanced Bactericidal Activity against Staphylococcus aureus In Vitro and In Vivo, Hang Yang, 2021
Linker Editing of Pneumococcal Lysin ClyJ Conveys Improved Bactericidal Activity, Hang Yang, 2020
Construction and characterization of a chimeric lysin ClyV with improved bactericidal activity against Streptococcus agalactiae in vitro and in vivo, Hang Yang, 2020
Can bacteriophage endolysins be nebulised for inhalation delivery against Streptococcus pneumoniae?, Hang Yang, 2020
A Choline-Recognizing Monomeric Lysin, ClyJ-3m, Shows Elevated Activity against Streptococcus pneumoniae, Hang Yang, 2020
A Novel Double Core-Shell Bionanoparticle Formed by Ferritin and Baculoviral Polyhedrin, Hang Yang, 2019
Construction of Lentivirus-Based Reference Material for RT-PCR Detection of Middle East Respiratory Syndrome Coronavirus and Its Application in External Quality Assessment, Hang Yang, 2019
ClyJ Is a Novel Pneumococcal Chimeric Lysin with a Cysteine- and Histidine-Dependent Amidohydrolase/Peptidase Catalytic Domain, Hang Yang, 2019
Effects of a Chimeric Lysin against Planktonic and Sessile Enterococcus faecalis Hint at Potential Application in Endodontic Therapy, Hang Yang, 2018
Staphylococcus aureus virulence attenuation and immune clearance mediated by a phage lysin‐derived protein, Hang Yang, 2018
Parallel susceptibility testing of bacteria through culture-quantitative pcr in 96-well plates, Hang Yang, 2018
Activity of the Chimeric Lysin ClyR against Common Gram-Positive Oral Microbes and Its Anticaries Efficacy in Rat Models, Hang Yang, 2018
Activity of the chimeric lysin clyr against common gram-positive oral microbes and its anticaries efficacy in rat models, Hang Yang, 2018
Effects of a Chimeric Lysin against Planktonic and Sessile Enterococcus faecalis Hint at Potential Application in Endodontic Therapy, Hang Yang, 2018
Accurate Detection of Methicillin-Resistant Staphylococcus aureus in Mixtures by Use of Single-Bacterium Duplex Droplet Digital PCR, Hang Yang, 2017
Rapid and selective detection of E. coli O157:H7 combining phagomagnetic separation with enzymatic colorimetry, Hang Yang, 2017
Combining phagomagnetic separation with immunoassay for specific, fast and sensitive detection of Staphylococcus aureus, Hang Yang, 2017
A novel chimeric lysin with robust antibacterial activity against planktonic and biofilm methicillin-resistant Staphylococcus aureus, Hang Yang, 2017
Comparison between a chimeric lysin ClyH and other enzymes for extracting DNA to detect methicillin resistant Staphylococcus aureus by quantitative PCR, Hang Yang, 2016
Antibiofilm Activities of a Novel Chimeolysin against Streptococcus mutans under Physiological and Cariogenic Conditions, Hang Yang, 2016
Sensitive and rapid detection of staphylococcus aureus in milk via cell binding domain of lysin, Hang Yang, 2016
Sensitive and rapid detection of staphylococcus aureus in milk via cell binding domain of lysin, Hang Yang, 2016
Rapid detection of viral antibodies based on multifunctional Staphylococcus aureus nanobioprobes, Hang Yang, 2016
Rapid and sensitive detection of hiv-1 p24 antigen by immunomagnetic separation coupled with catalytic fluorescent immunoassay, Hang Yang, 2016
Anti-biofilm activities of a novel chimeolysin against S. mutans in physiological and cariogenic conditions, Hang Yang, 2016
Molecular dissection of phage lysin PlySs2: integrity of the catalytic and cell wall binding domains is essential for its broad lytic activity, Hang Yang, 2015
Research progress in lysin therapy, Hang Yang, 2015
Study of the interactions between endolysin and bacterial peptidoglycan on S. aureus by dynamic force spectroscopy, Hang Yang, 2015
Molecular dissection of phage lysin PlySs2: integrity of the catalytic and cell wall binding domains is essential for its broad lytic activity, Hang Yang, 2015
Construction of a chimeric lysin Ply187N-V12C with extended lytic activity against staphylococci and streptococci, Hang Yang, 2015
Isolation and complete genome sequence of a novel virulent mycobacteriophage, CASbig, Hang Yang, 2015
Aspartate inhibits Staphylococcus aureus biofilm formation, Hang Yang, 2015
Area of Focus
Microbiology | Genomics | Biotechnology | Protein Production | Enzyme Production | Molecular Breeding | Biodegradable | Polymers | Drug Carriers | Industrial Applications