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Cheng Zhou
Life Science
University of Chinese Academy of Sciences
Beijing
Language: Chinese, English
Extremophiles
Enzymes
Biotechnology
Microbial Cell Factories
Genetic Engineering
Industrial Applications
Biocatalysis
Protein Engineering
Metabolic Pathways
Synthetic Biology
Areas of Focus
- Extreme Enzymes and Extremophilic Microbial Cell Factories
Work Experience
- 2018-09~Present - Institute of Microbiology, Chinese Academy of Sciences - Associate Researcher
- 2010-03~2018-08 - Institute of Microbiology, Chinese Academy of Sciences - Assistant Researcher
- 2002-09~2010-01 - Institute of Microbiology, Chinese Academy of Sciences - PhD in Science
- 1998-09~2002-07 - School of Life Sciences, Nankai University - Bachelor's in Science
Academic Background & Achievements
- 2002-09--2010-01 PhD in Science: Institute of Microbiology, Chinese Academy of Sciences
- 1998-09--2002-07 Bachelor's in Science: School of Life Sciences, Nankai University
Publications
- A Review of the Recent Developments in the Bioproduction of Polylactic Acid and Its Precursors Optically Pure Lactic Acids, 11th Author, 2021
- Enzymatic characterization of a novel thermostable and alkaline tolerant GH10 xylanase and activity improvement by multiple rational mutagenesis strategies, 11th Author, 2021
- 芽孢杆菌N1碱性蛋白酶的克隆表达及酶学性质, 2nd Author, 2018
- Cloning, expression, and characterization of an alkaline protease, AprV, from Vibrio sp DA1-1, 11th Author, 2018
- A novel alkaline protease from alkaliphilic Idiomarina sp C9-1 with potential application for eco-friendly enzymatic dehairing in the leather industry, 11th Author, 2018
- Coralloluteibacterium thermophilus sp nov., A Gammaproteobacterium Isolated from an Oil Reservoir, 11th Author, 2018
- Characterization and high-efficiency secreted expression in Bacillus subtilis of a thermo-alkaline beta-mannanase from an alkaliphilic Bacillus clausii strain S10, 1st Author, 2018
- Characterization and overproduction of a thermo-alkaline pectate lyase from alkaliphilic Bacillus licheniformis with potential in ramie degumming, 1st Author, 2017
- Cloning, evaluation, and high-level expression of a thermo-alkaline pectate lyase from alkaliphilic Bacillus clausii with potential in ramie degumming, 1st Author, 2017
- Non-sterilized fermentation of high optically pure d -lactic acid by a genetically modified thermophilic Bacillus coagulans strain, 2nd Author, 2017
- Improving the thermoactivity and thermostability of pectate lyase from Bacillus pumilus for ramie degumming, 3rd Author, 2015
- Structural Insight into and Mutational Analysis of Family 11 Xylanases: Implications for Mechanisms of Higher pH Catalytic Adaptation, 2nd Author, 2015
- Cloning, expression, and characterization of a novel alkali-tolerant xylanase from alkaliphilic Bacillus sp SN5, 3rd Author, 2015
- Evaluation and directed evolution for thermostability improvement of a GH 13 thermostable alpha-glucosidase from Thermus thermophilus TC11, 1st Author, 2015
- Directed Evolution and Structural Analysis of Alkaline Pectate Lyase from the Alkaliphilic Bacterium Bacillus sp Strain N16-5 To Improve Its Thermostability for Efficient Ramie Degumming, 1st Author, 2015
- Identification and characterization of a novel salt-tolerant esterase from a Tibetan glacier metagenomic library, 6th Author, 2015
- Cloning, expression and characterization of a pectate lyase from Paenibacillus sp 0602 in recombinant Escherichia coli, 3rd Author, 2014
- Three-dimensional structure of an alkaline xylanase Xyn11A-LC from alkalophilic Bacillus sp SN5 and improvement of its thermal performance by introducing arginines substitutions, 2nd Author, 2014
- The alkaline pectate lyase PEL168 of Bacillus subtilis heterologously expressed in Pichia pastoris is more stable and efficient for degumming ramie fiber, 3rd Author, 2013
- Crystal structure and substrate-binding mode of a novel pectate lyase from alkaliphilic Bacillus sp N16-5, 6th Author, 2012
- Cloning, expression and characterization of a novel salt-tolerant xylanase from Bacillus sp SN5, 3rd Author, 2012
- Molecular cloning and heterologous expression of an acid stable xylanase gene from Alternaria sp HB186, Not mentioned, 2012
- Cloning and characterization of a thermostable and halo-tolerant endoglucanase from Thermoanaerobacter tengcongensis MB4, 5th Author, 2011
- A thermostable esterase from Thermoanaerobacter tengcongensis opening up a new family of bacterial lipolytic enzymes, 3rd Author, 2011
- Enhancing the thermostability of alpha-glucosidase from thermoanaerobacter tengcongensis mb4 by single proline substitution, 1st Author, 2010
- Cloning, expression, and characterization of a thermostable glucoamylase from Thermoanaerobacter tengcongensis MB4, 4th Author, 2010
- Cloning, Expression, and Characterization of a Highly Active Alkaline Pectate Lyase from Alkaliphilic Bacillus sp N16-5, 4th Author, 2010
- 嗜碱Bacillus sp.N16-5不同碳源条件下比较蛋白质组分析, 5th Author, 2010
- 腾冲嗜热菌MB4和嗜热栖热菌TC11S耐热α-葡萄糖苷酶性质、定向进化与热稳定性研究, 1st Author, 2009
- Recombinant Expression and Characterization of Thermoanaerobacter tengcongensis Thermostable alpha-Glucosidase with Regioselectivity for High-Yield Isomaltooligosaccharides Synthesis, 1st Author, 2009
- Biochemical and Structural Characterization of the Intracellular Mannanase AaManA of Alicyclobacillus acidocaldarius Reveals a Novel Glycoside Hydrolase Family Belonging to Clan GH-A*, 5th Author, 2008
- Salinicoccus halodurans sp nov., a moderate halophile from saline soil in China, 4th Author, 2008
- 嗜热栖热菌α-葡萄糖苷酶基因的表达及酶学性质研究, 2nd Author, 2007
- Caldalkalibacillus thermarum gen. nov., sp nov., a novel alkalithermophilic bacterium from a hot spring in China, Not mentioned, 2006
- 内蒙古锡林浩特地区嗜盐古菌多样性的研究, 2nd Author, 2006
Awards
- China Industry-University-Research Cooperation Innovation Achievement Award, Second Prize, Ministerial Level, 2021
- China National Textile and Apparel Council Science and Technology Progress Award, Second Prize, Ministerial Level, 2021
- National Commercial Science and Technology Progress Award, Second Prize, Ministerial Level, 2021
- Key Technology and Application of Isomaltooligosaccharide Industrialization, First Prize, Ministerial Level, 2015
