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Gang Zhang
Life Science
University of Chinese Academy of Sciences
Beijing
Language: Chinese, English
Pathogenic Bacteria
Drug Resistance
Phage Defense
Mechanisms
Microbiology
Antibiotics
Crispr
Genomic Islands
Integrases
Gene Transfer
Areas of Focus
- Pathogenic Bacteria Drug Resistance and Phage Defense Mechanisms
Work Experience
- 2018-10~Present - Chinese Academy of Sciences, Institute of Microbiology - Associate Researcher
- 2011-07~2018-10 - Chinese Academy of Sciences, Institute of Microbiology - Assistant Researcher
Academic Background & Achievements
- 2008-09--2011-06 PhD: China Agricultural University
- 2005-09--2008-06 Master's: Shihezi University
- 2001-09--2005-06 Bachelor's: Shihezi University
Publications
- Harnessing the Native Type I-F CRISPR-Cas System of Acinetobacter baumannii for Genome Editing and Gene Repression, 11th Author, 2023
- Systematic Discovery of a New Catalogue of Tyrosine-Type Integrases in Bacterial Genomic Islands, 1st Author, 2023
- IS26 Veers Genomic Plasticity and Genetic Rearrangement toward Carbapenem Hyperresistance under Sublethal Antibiotics (vol 13, e03340-21, 2022), 4th Author, 2022
- In vivo evolution of carbapenem resistance in hypervirulent Klebsiella pneumoniae in a patient undergoing long-term treatment, 6th Author, 2022
- An urban soil environmental E. coli ST354 isolate co-harbouring mcr-1 and bla NDM-9, 4th Author, 2022
- Amplification of bla(NDM-1) mediated by ISCR1 confers hyperresistance to carbapenem, 4th Author, 2022
- The integrase of genomic island GIsul2 mediates the mobilization of GIsul2 and ISCR-related element CR2-sul2 unit through site-specific recombination, 1st Author, 2022
- IS 26 Veers Genomic Plasticity and Genetic Rearrangement toward Carbapenem Hyperresistance under Sublethal Antibiotics, 4th Author, 2022
- Efficient Suppression of Natural Plasmid-Borne Gene Expression in Carbapenem-Resistant Klebsiella pneumoniae Using a Compact CRISPR Interference System, 11th Author, 2022
- Streptococcus sputorum , a Novel Member of Streptococcus with Multidrug Resistance, Exhibits Cytotoxicity, 6th Author, 2021
- The Shared Resistome of Human and Pig Microbiota Is Mobilized by Distinct Genetic Elements, 4th Author, 2021
- Systematic analysis of supervised machine learning as an effective approach to predicate beta-lactam resistance phenotype in Streptococcus pneumoniae, 5th Author, 2020
- A new intrinsic aminoglycoside 6 '-N-acetyltransferase subclass, AAC(6 ')-III, in Burkholderia pseudomallei, Burkholderia mallei and Burkholderia oklahomensis, 1st Author, 2020
- Co-existence of the carbapenem resistance genes blaKPC-2 and blaNDM-1 in a Raoultella planticola isolate in China, 7th Author, 2020
- A novel family of intrinsic chloramphenicol acetyltransferase CATC in Vibrio parahaemolyticus: naturally occurring variants reveal diverse resistance levels against chloramphenicol, 1st Author, 2019
- Real time monitoring of Aeromonas salmonicida evolution in response to successive antibiotic therapies in a commercial fish farm, 6th Author, 2019
- 细菌中基因组岛的转移与调控机制研究进展, Regulation, excision and horizontal transfer of genomic islands in bacteria, 2nd Author, 2018
- Five novel carbapenem-hydrolysing OXA-type beta-lactamase groups are intrinsic in Acinetobacter spp., 2nd Author, 2018
- A new subclass of intrinsic aminoglycoside nucleotidyltransferases, ANT(3\, 2017
- Iscr2 is associated with the dissemination of multiple resistance genes among vibrio spp. and pseudoalteromonas spp. isolated from farmed fish, 3rd Author, 2017
- 细菌固有耐药的研究进展, The intrinsic resistance of bacteria, 1st Author, 2016
- Identification of Novel Cryptic Aminoglycoside Phosphotransferases in Pseudomonas aeruginosa, 1st Author, 2016
- Insights into the evolutionary trajectories of fluoroquinolone resistance in Streptococcus pneumoniae, 1st Author, 2015
- Functional characterization and phylogenetic analysis of acquired and intrinsic macrolide phosphotransferases in the Bacillus cereus group, 4th Author, 2015
- Mechanism for transfer of transposon Tn2010 carrying macrolide resistance genes in Streptococcus pneumoniae and its effects on genome evolution, 3rd Author, 2014
- Characterization of a Multiresistant Mosaic Plasmid from a Fish Farm Sediment Exiguobacterium sp. Isolate Reveals Aggregation of Functional Clinic-Associated Antibiotic Resistance Genes, 5th Author, 2014
- 肺炎链球菌对氟喹诺酮类抗生素耐药研究进展, Research progress in Streptococcus Pneumoniae resistance to fluoroquinolone antibiotics, 1st Author, 2014
- Identification of a novel resistance mutation in parE that confers high-level resistance to moxifloxacin in Streptococcus pneumoniae, 1st Author, 2012
