Professor | 张刚 | 数字化转型顾问

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Name	张刚
Contact Information	zhanggang@im.ac.cn
Language ability	中文, 英语
Province	北京

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Name

张刚

Contact Information

zhanggang@im.ac.cn

Language ability

中文, 英语

Province

北京

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2008-09--2011-06 博士: 中国农业大学 2005-09--2008-06 硕士: 石河子大学 2001-09--2005-06 学士: 石河子大学
Work Experience	2018-10~现在 - 中国科学院微生物研究所 - 副研究员 2011-07~2018-10 - 中国科学院微生物研究所 - 助理研究员

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2008-09--2011-06 博士: 中国农业大学
2005-09--2008-06 硕士: 石河子大学
2001-09--2005-06 学士: 石河子大学

Work Experience

2018-10~现在 - 中国科学院微生物研究所 - 副研究员
2011-07~2018-10 - 中国科学院微生物研究所 - 助理研究员

Areas of Focus	病原菌耐药与噬菌体防御机制
Publications	Harnessing the Native Type I-F CRISPR-Cas System of Acinetobacter baumannii for Genome Editing and Gene Repression, 第11作者, 2023 Systematic Discovery of a New Catalogue of Tyrosine-Type Integrases in Bacterial Genomic Islands, 第1作者, 2023 IS26 Veers Genomic Plasticity and Genetic Rearrangement toward Carbapenem Hyperresistance under Sublethal Antibiotics (vol 13, e03340-21, 2022), 第4作者, 2022 In vivo evolution of carbapenem resistance in hypervirulent Klebsiella pneumoniae in a patient undergoing long-term treatment, 第6作者, 2022 An urban soil environmental E. coli ST354 isolate co-harbouring mcr-1 and bla NDM-9, 第4作者, 2022 Amplification of bla(NDM-1) mediated by ISCR1 confers hyperresistance to carbapenem, 第4作者, 2022 The integrase of genomic island GIsul2 mediates the mobilization of GIsul2 and ISCR-related element CR2-sul2 unit through site-specific recombination, 第1作者, 2022 IS 26 Veers Genomic Plasticity and Genetic Rearrangement toward Carbapenem Hyperresistance under Sublethal Antibiotics, 第4作者, 2022 Efficient Suppression of Natural Plasmid-Borne Gene Expression in Carbapenem-Resistant Klebsiella pneumoniae Using a Compact CRISPR Interference System, 第11作者, 2022 Streptococcus sputorum , a Novel Member of Streptococcus with Multidrug Resistance, Exhibits Cytotoxicity, 第6作者, 2021 The Shared Resistome of Human and Pig Microbiota Is Mobilized by Distinct Genetic Elements, 第4作者, 2021 Systematic analysis of supervised machine learning as an effective approach to predicate beta-lactam resistance phenotype in Streptococcus pneumoniae, 第5作者, 2020 A new intrinsic aminoglycoside 6 '-N-acetyltransferase subclass, AAC(6 ')-III, in Burkholderia pseudomallei, Burkholderia mallei and Burkholderia oklahomensis, 第1作者, 2020 Co-existence of the carbapenem resistance genes blaKPC-2 and blaNDM-1 in a Raoultella planticola isolate in China, 第7作者, 2020 A novel family of intrinsic chloramphenicol acetyltransferase CATC in Vibrio parahaemolyticus: naturally occurring variants reveal diverse resistance levels against chloramphenicol, 第1作者, 2019 Real time monitoring of Aeromonas salmonicida evolution in response to successive antibiotic therapies in a commercial fish farm, 第6作者, 2019 细菌中基因组岛的转移与调控机制研究进展, Regulation, excision and horizontal transfer of genomic islands in bacteria, 第2作者, 2018 Five novel carbapenem-hydrolysing OXA-type beta-lactamase groups are intrinsic in Acinetobacter spp., 第2作者, 2018 A new subclass of intrinsic aminoglycoside nucleotidyltransferases, ANT(3\, 2017 Iscr2 is associated with the dissemination of multiple resistance genes among vibrio spp. and pseudoalteromonas spp. isolated from farmed fish, 第3作者, 2017 细菌固有耐药的研究进展, The intrinsic resistance of bacteria, 第1作者, 2016 Identification of Novel Cryptic Aminoglycoside Phosphotransferases in Pseudomonas aeruginosa, 第1作者, 2016 Insights into the evolutionary trajectories of fluoroquinolone resistance in Streptococcus pneumoniae, 第1作者, 2015 Functional characterization and phylogenetic analysis of acquired and intrinsic macrolide phosphotransferases in the Bacillus cereus group, 第4作者

Areas of Focus

病原菌耐药与噬菌体防御机制

Publications

Harnessing the Native Type I-F CRISPR-Cas System of Acinetobacter baumannii for Genome Editing and Gene Repression, 第11作者, 2023
Systematic Discovery of a New Catalogue of Tyrosine-Type Integrases in Bacterial Genomic Islands, 第1作者, 2023
IS26 Veers Genomic Plasticity and Genetic Rearrangement toward Carbapenem Hyperresistance under Sublethal Antibiotics (vol 13, e03340-21, 2022), 第4作者, 2022
In vivo evolution of carbapenem resistance in hypervirulent Klebsiella pneumoniae in a patient undergoing long-term treatment, 第6作者, 2022
An urban soil environmental E. coli ST354 isolate co-harbouring mcr-1 and bla NDM-9, 第4作者, 2022
Amplification of bla(NDM-1) mediated by ISCR1 confers hyperresistance to carbapenem, 第4作者, 2022
The integrase of genomic island GIsul2 mediates the mobilization of GIsul2 and ISCR-related element CR2-sul2 unit through site-specific recombination, 第1作者, 2022
IS 26 Veers Genomic Plasticity and Genetic Rearrangement toward Carbapenem Hyperresistance under Sublethal Antibiotics, 第4作者, 2022
Efficient Suppression of Natural Plasmid-Borne Gene Expression in Carbapenem-Resistant Klebsiella pneumoniae Using a Compact CRISPR Interference System, 第11作者, 2022
Streptococcus sputorum , a Novel Member of Streptococcus with Multidrug Resistance, Exhibits Cytotoxicity, 第6作者, 2021
The Shared Resistome of Human and Pig Microbiota Is Mobilized by Distinct Genetic Elements, 第4作者, 2021
Systematic analysis of supervised machine learning as an effective approach to predicate beta-lactam resistance phenotype in Streptococcus pneumoniae, 第5作者, 2020
A new intrinsic aminoglycoside 6 '-N-acetyltransferase subclass, AAC(6 ')-III, in Burkholderia pseudomallei, Burkholderia mallei and Burkholderia oklahomensis, 第1作者, 2020
Co-existence of the carbapenem resistance genes blaKPC-2 and blaNDM-1 in a Raoultella planticola isolate in China, 第7作者, 2020
A novel family of intrinsic chloramphenicol acetyltransferase CATC in Vibrio parahaemolyticus: naturally occurring variants reveal diverse resistance levels against chloramphenicol, 第1作者, 2019
Real time monitoring of Aeromonas salmonicida evolution in response to successive antibiotic therapies in a commercial fish farm, 第6作者, 2019
细菌中基因组岛的转移与调控机制研究进展, Regulation, excision and horizontal transfer of genomic islands in bacteria, 第2作者, 2018
Five novel carbapenem-hydrolysing OXA-type beta-lactamase groups are intrinsic in Acinetobacter spp., 第2作者, 2018
A new subclass of intrinsic aminoglycoside nucleotidyltransferases, ANT(3\, 2017
Iscr2 is associated with the dissemination of multiple resistance genes among vibrio spp. and pseudoalteromonas spp. isolated from farmed fish, 第3作者, 2017
细菌固有耐药的研究进展, The intrinsic resistance of bacteria, 第1作者, 2016
Identification of Novel Cryptic Aminoglycoside Phosphotransferases in Pseudomonas aeruginosa, 第1作者, 2016
Insights into the evolutionary trajectories of fluoroquinolone resistance in Streptococcus pneumoniae, 第1作者, 2015
Functional characterization and phylogenetic analysis of acquired and intrinsic macrolide phosphotransferases in the Bacillus cereus group, 第4作者

病原菌耐药性噬菌体防御机制微生物学抗生素 Crispr 基因组岛整合酶基因转移

肖毅 - 上海交通大学

陈春来 - 清华大学

Area of Focus
荧光 | 单分子 | 技术 | 蛋白 | Dna | 靶向 | 机制 | Crispr | 剪切 | 研究

陈春来 - 清华大学

Area of Focus
荧光 | 单分子 | 技术 | 蛋白 | Dna | 靶向 | 机制 | Crispr | 剪切 | 研究

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