Areas of Focus
- Systems Biology
- Alzheimer's Disease
- Stem Cells
- Big Data
Work Experience
- 2003-08~2008-06 - University of Delaware/University of California, Davis - Postdoctoral/Research Group Leader
- 1991-07~1998-06 - Academy of Military Medical Sciences - Assistant Researcher
Academic Background & Achievements
- 1998-08--2003-05 PhD in Biochemistry: Kansas State University
- 1987-09--1991-06 Bachelor's in Engineering: Huazhong University of Science and Technology
Publications
- A two-gene marker for the two-tiered innate immune response in COVID-19 patients, Hongxing Lei, 2022
- Single-cell RNA-Seq revealed profound immune alteration in the peripheral blood of patients with bacterial infection, Lei, Hongxing, Wang, Chi, Wang, Yunlai, Wang, Chengbin, 2021
- A host-based two-gene model for the identification of bacterial infection in general clinical settings, Lei, Hongxing, Xu, Xiaoyue, Wang, Chi, Xue, Dandan, Wang, Chengbin, Chen, Jiankui, 2021
- A single transcript for the prognosis of disease severity in COVID-19 patients, Hongxing Lei, 2021
- Big Data and the Brain: Peeking at the Future, Hongzhu Qu, Hongxing Lei, Xiangdong Fang, 2019
- Gene dysregulation in peripheral blood of moyamoya disease and comparison with other vascular disorders, Xing Peng, Zhengshan Zhang, Dongqing Ye, Peiqi Xing, Zhengxing Zou, Hongxing Lei, Lian Duan, 2019
- Evaluation of Peripheral Immune Dysregulation in Alzheimer's Disease and Vascular Dementia, Guo, Zongjun, Peng, Xing, Li, HuiYun, Wang, Yunlai, Qian, Ying, Wang, Zhihong, Ye, Dongqing, Ji, Xiaoyun, Wang, Zhixin, Wang, Yanjiang, Chen, Dongwan, Lei, Hongxing, 2019
- GSA: Genome Sequence Archive, Wang, Yanqing, Song, Fuhai, Zhu, Junwei, Zhang, Sisi, Yang, Yadong, Chen, Tingting, Tang, Bixia, Dong, Lili, Ding, Nan, Zhang, Qian, Bai, Zhouxian, Dong, Xunong, Chen, Huanxin, Sun, Mingyuan, Zhai, Shuang, Sun, Yubin, Yu, Lei, Lan, Li, Xiao, Jingfa, Fang, Xiangdong, Lei, Hongxing, Zhang, Zhang, Zhao, Wenming, 2017
- The frontline of immune response in peripheral blood, Song, Fuhai, Qian, Ying, Peng, Xing, Li, Xiuhui, Xing, Peiqi, Ye, Dongqing, Lei, Hongxing, 2017
- Perturbation of the transcriptome: implications of the innate immune system in Alzheimer's disease, Song, Fuhai, Qian, Ying, Peng, Xing, Han, Guangchun, Wang, Jiajia, Bai, Zhouxian, Crack, Peter J, Lei, Hongxing, 2016
- AlzBase: an Integrative Database for Gene Dysregulation in Alzheimer's Disease, Bai, Zhouxian, Han, Guangchun, Xie, Bin, Wang, Jiajia, Song, Fuhai, Peng, Xing, Lei, Hongxing, 2016
- Alzheimer's Disease: Genomics and Beyond, Song, Fuhai, Han, Guangchun, Bai, Zhouxian, Peng, Xing, Wang, Jiajia, Lei, Hongxing, Hurley, MJ, 2015
- Chromosome 19p in Alzheimer's Disease: When Genome Meets Transcriptome, Wang, Jiajia, Feng, Xuemei, Bai, Zhouxian, Jin, LeeWay, Duan, Yong, Lei, Hongxing, 2014
- Conformational Elasticity can Facilitate TALE DNA Recognition, Lei, Hongxing, Sun, Jiya, Baldwin, Enoch P, Segal, David J, Duan, Yong, Donev, R, 2014
- Hidden Risk Genes with High-Order Intragenic Epistasis in Alzheimer's Disease, Sun, Jiya, Song, Fuhai, Wang, Jiajia, Han, Guangchun, Bai, Zhouxian, Xie, Bin, Feng, Xuemei, Jia, Jianping, Duan, Yong, Lei, Hongxing, 2014
- Characteristic Transformation of Blood Transcriptome in Alzheimer's Disease, Han, Guangchun, Wang, Jiajia, Zeng, Fan, Feng, Xuemei, Yu, Jun, Cao, HongYuan, Yi, Xu, Zhou, Huadong, Jin, LeeWay, Duan, Yong, Wang, YanJiang, Lei, Hongxing, 2013
- The functional network of human divergently paired genes (DPGs), Lei Hongxing, 2013
- iBIG: An Integrative Network Tool for Supporting Human Disease Mechanism Studies, Sun Jiya, Pan Yuyun, Feng Xuemei, Zhang Huijuan, Duan Yong, Lei Hongxing, 2013
- Concerted Perturbation Observed in a Hub Network in Alzheimer's Disease, Liang, Dapeng, Han, Guangchun, Feng, Xuemei, Sun, Jiya, Duan, Yong, Lei, Hongxing, 2012
- Down-Regulation of Energy Metabolism in Alzheimer's Disease is a Protective Response of Neurons to the Microenvironment, Sun, Jiya, Feng, Xuemei, Liang, Dapeng, Duan, Yong, Lei, Hongxing, 2012
