Professor | Shuangli Mi | Asia Growth Partners

Name	Shuangli Mi
Contact Information	mishl@big.ac.cn
Language ability	Chinese, English
Province	Beijing

Name

Shuangli Mi

Contact Information

mishl@big.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	1999-09 to 2005-07 PhD: Peking University
Work Experience	2005-07 to 2009-07 - University of Chicago - Postdoctoral Researcher in Hematology and Pharmacogenomics 2008-08 to Present - Beijing Institute of Genomics, Chinese Academy of Sciences - Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

1999-09 to 2005-07 PhD: Peking University

Work Experience

2005-07 to 2009-07 - University of Chicago - Postdoctoral Researcher in Hematology and Pharmacogenomics
2008-08 to Present - Beijing Institute of Genomics, Chinese Academy of Sciences - Researcher

Areas of Focus	Cancer Genomics Pharmacogenomics
Publications	Piperine promotes PI3K/AKT/mTOR-mediated gut-brain autophagy to degrade α-Synuclein in Parkinson’s disease rats., Lan Yu, Xiaolu Hu, Rongrong Xu, Yimeng Zhao, Lijuan Xiong, Jiaxuan Ai, Xing Wang, Xiaoqing Chen, Yinying Ba, Zhikai Xing, Chongye Guo, Shuangli Mi, Xia Wu, 2024 Implication of a de novo Variant in ciliary rootlet coiled- coil (CROCC) with assimilation of atlas (AOA)., Huaiyu Tong, Chongye Guo, Liang Liang, Hua Mi, Meng Li, Yiheng Yin, Lijun Shang, Shuangli Mi, Xinguang Yu, 2022 Disequilibrium in chicken gut microflora with avian colibacillosis is related to microenvironment damaged by antibiotics., Xing, Zhikai, Li, Hui, Li, Meng, Gao, Ran, Guo, Chongye, Mi, Shuangli, 2021 Heterogeneous Nuclear Ribonucleoprotein A1 Loads Batched Tumor-Promoting MicroRNAs Into Small Extracellular Vesicles With the Assist of Caveolin-1 in A549 Cells., Li, Yangyang, Zhang, Jian, Li, Sha, Guo, Chongye, Li, Qian, Zhang, Xin, Li, Meng, Mi, Shuangli, 2021 The long noncoding RNA HOTAIRM1 controlled by AML1 enhances glucocorticoid resistance by activating RHOA/ROCK1 pathway through suppressing ARHGAP18., Liang, Liang, Gu, Wenbin, Li, Meng, Gao, Ran, Zhang, Xin, Guo, Chongye, Mi, Shuangli, 2021 Identification of Potential Key lncRNAs in the Context of Mouse Myeloid Differentiation by Systematic Transcriptomics Analysis., Lan, Yongqing, Li, Meng, Mi, Shuangli, 2021 Dietary Intervention With α-Amylase Inhibitor in White Kidney Beans Added Yogurt Modulated Gut Microbiota to Adjust Blood Glucose in Mice., Shenli Wang, Chongye Guo, Zhikai Xing, Meng Li, Haiying Yang, Yunting Zhang, Fazheng Ren, Lishui Chen, Shuangli Mi, 2021 Secretome of Activated Fibroblasts Induced by Exosomes for the Discovery of Biomarkers in Non-Small Cell Lung Cancer., Zhang, Jian, Fu, Bin, Li, Meng, Mi, Shuangli, 2021 miR-218-2 regulates cognitive functions in the hippocampus through complement component 3-dependent modulation of synaptic vesicle release., Lu, SiYao, Fu, ChongLei, Liang, Liang, Yang, Bo, Shen, Wei, Wang, QiuWen, Chen, Yun, Chen, YanFen, Liu, YaoNan, Zhu, Lin, Zhao, Jieqing, Shi, Wei, Mi, Shuangli, Yao, Jun, 2021 Tumor-derived circulating exosomal miR-342-5p and miR-574-5p as promising diagnostic biomarkers for early-stage Lung Adenocarcinoma., Han, Zhijun, Li, Yangyang, Zhang, Jian, Guo, Chongye, Li, Qian, Zhang, Xin, Lan, Yongqing, Gu, Wenbin, Xing, Zhikai, Liang, Liang, Li, Meng, Mi, Shuangli, 2020 A promising iPS-based single-cell cloning strategy revealing signatures of somatic mutations in heterogeneous normal cells., Miao, Xuexia, Li, Yueying, Zheng, Caihong, Wang, Lifei, Jin, Chen, Chen, Lei, Mi, Shuangli, Zhai, Weiwei, Wang, QianFei, Cai, Jun, 2020 Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice., Shen, Wei, Wang, QiuWen, Liu, YaoNan, Marchetto, Maria C, Linker, Sara, Lu, SiYao, Chen, Yun, Liu, Chuihong, Guo, Chongye, Xing, Zhikai, Shi, Wei, Kelsoe, John R, Alda, Martin, Wang, Hongwei, Zhong, Yi, Sui, SenFang, Zhao, Mei, Yang, Yiming, Mi, Shuangli, Cao, Liping, Gage, Fred H, Yao, Jun, 2020 RBUD: A New Functional Potential Analysis Approach for Whole Microbial Genome Shotgun Sequencing., Xing, Zhikai, Zhang, Yunting, Li, Meng, Guo, Chongye, Mi, Shuangli, 2020 植物益生元对肠道菌群的调节及对机体糖代谢吸收的影响., 郭翀晔, 邢志凯, 李蒙, 胡晓璐, 吴霞, 陈历水, 米双利, 2019 中药对肠道菌群的调节作用., 于岚, 邢志凯, 米双利, 吴霞, 2019 CRISPR interference-based specific and efficient gene inactivation in the brain (vol 21, pg 447, 2018)., Zheng, Yi, Shen, Wei, Zhang, Jian, Yang, Bo, Liu, YaoNan, Qi, Huihui, Yu, Xia, Lu, SiYao, Chen, Yun, Xu, YuZhou, Li, Yun, Gage, Fred H, Mi, Shuangli, Yao, Jun, 2018 CRISPR interference-based specific and efficient gene inactivation in the brain., Zheng, Yi, Shen, Wei, Zhang, Jian, Yang, Bo, Liu, YaoNan, Qi, Huihui, Yu, Xia, Lul, SiYao, Chen, Yun, Xu, YuZhou, Lp, Yun, Gage, Fred H, Mi, Shuangli, Yao, Jun, 2018 Early different downstream target of glucocorticoid receptor contributing to Glucocorticoids sensitivity in Kasumi-1 cells. (ASH meeting)., Mi Shuangli, 2016 Base-excision repair and beyond -A short summary attributed to scientific achievements of Tomas Lindahl, Nobel Prize Laureate in Chemistry 2015., Mi, Shuangli, Klungland, Arne, Yang, YunGui, 2016 Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function., Zhang, Jian, Li, Sha, Li, Lu, Li, Meng, Guo, Chongye, Yao, Jun, Mi, Shuangli, 2015 Circulating MicroRNAs as Biomarkers for Inflammatory Diseases., Shuangli Mi, Jian Zhang, Wei Zhang, R Stephanie Huang, 2013 孕期暴露因素与新生儿血管瘤发生的关联性研究., 王琳, 米双利, 陈杰, 刘芳, 李迎春, 郭彩虹, 张勇, 范钦颖, 2012 An eQTL-based method identifies CTTN and ZMAT3 as pemetrexed susceptibility markers., Wen, Yujia, Gamazon, Eric R, Bleibel, Wasim K, Wing, Claudia, Mi, Shuangli, McIlwee, Bridget E, Delaney, Shannon M, Duan, Shiwei, Im, Hae Kyung, Dolan, M Eileen, 2012 新生儿血管瘤发生的高危因素., 米双利, 2012 MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome., Wang, Qianfei, Wu, George, Mi, Shuangli, He, Fuhong, Wu, Jun, Dong, Jingfang, Luo, Roger T, Mattison, Ryan, Kaberlein, Joseph J, Prabhakar, Shyam, Ji, Hongkai, Thirman, Michael J, 2011 Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia., Mi, Shuangli, Li, Zejuan, Chen, Ping, He, Chunjiang, Cao, Donglin, Elkahloun, Abdel, Lu, Jun, Pelloso, Luis A, Wunderlich, Mark, Huang, Hao, Luo, Roger T, Sun, Miao, He, Miao, Neilly, Mary Beth, ZeleznikLe, Nancy J, Thirman, Michael J, Mulloy, James C, Liu, Paul P, Rowley, Janet D, Chen, Jianjun, 2010 Comprehensive analysis of the impact of SNPs and CNVs on human microRNAs and their regulatory genes., Duan, Shiwei, Mi, Shuangli, Zhang, Wei, Dolan, M Eileen, 2009 Consistent Deregulation of Gene Expression between Human and Murine MLL Rearrangement Leukemias., Li, Zejuan, Luo, Roger T, Mi, Shuangli, Sun, Miao, Chen, Ping, Bao, Jingyue, Neilly, Mary Beth, Jayathilaka, Nimanthi, Johnson, Deborah S, Wang, Lili, Lavau, Catherine, Zhang, Yanming, Tseng, Charles, Zhang, Xiuqing, Wang, Jian, Yu, Jun, Yang, Huanming, Wang, San Ming, Rowley, Janet D, Chen, Jianjun, Thirman, Michael J, 2009 Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity., Hartford, Christine M, Duan, Shiwei, Delaney, Shannon M, Mi, Shuangli, Kistner, Emily O, Lamba, Jatinder K, Huang, R Stephanie, Dolan, M Eileen, 2009 Candidate genes pharmacogenetics of anti-cancer agents., Mi Shuangli, 2009 Expression and alternative splicing of folate pathway genes in HapMap lymphoblastoid cell lines., Duan, Shiwei, Huang, R Stephanie, Zhang, Wei, Mi, Shuangli, Bleibel, Wasim K, Kistner, Emily O, Cox, Nancy J, Dolan, M Eileen, 2009 Distinct microRNA expression profiles in acute myeloid leukemia with common translocations., Li, Zejuan, Lu, Jun, Sun, Miao, Mi, Shuangli, Zhang, Hao, Luo, Roger T, Chen, Ping, Wang, Yungui, Yan, Ming, Qian, Zhijian, Neilly, Mary Beth, Jin, Jie, Zhang, Yanming, Bohlander, Stefan K, Zhang, DongEr, Larson, Richard A, Le Beau, Michelle M, Thirman, Michael J, Golub, Todd R, Rowley, Janet D, Chen, Jianjun, 2008 Recent patents on the identification and clinical application of microRNAs and target genes., Mi Shuangli, 2007 MicroRNA Expression Signatures Accurately Discriminate Acute Lymphoblastic Leukemia from Acute Myeloid Leukemia., Shuangli Mi PhD, Jun Lu PhD, Miao Sun MS, Zejuan Li PhD, Hao Zhang MS, Mary Beth Neilly MS,

Areas of Focus

Cancer Genomics
Pharmacogenomics

Publications

Piperine promotes PI3K/AKT/mTOR-mediated gut-brain autophagy to degrade α-Synuclein in Parkinson’s disease rats., Lan Yu, Xiaolu Hu, Rongrong Xu, Yimeng Zhao, Lijuan Xiong, Jiaxuan Ai, Xing Wang, Xiaoqing Chen, Yinying Ba, Zhikai Xing, Chongye Guo, Shuangli Mi, Xia Wu, 2024
Implication of a de novo Variant in ciliary rootlet coiled- coil (CROCC) with assimilation of atlas (AOA)., Huaiyu Tong, Chongye Guo, Liang Liang, Hua Mi, Meng Li, Yiheng Yin, Lijun Shang, Shuangli Mi, Xinguang Yu, 2022
Disequilibrium in chicken gut microflora with avian colibacillosis is related to microenvironment damaged by antibiotics., Xing, Zhikai, Li, Hui, Li, Meng, Gao, Ran, Guo, Chongye, Mi, Shuangli, 2021
Heterogeneous Nuclear Ribonucleoprotein A1 Loads Batched Tumor-Promoting MicroRNAs Into Small Extracellular Vesicles With the Assist of Caveolin-1 in A549 Cells., Li, Yangyang, Zhang, Jian, Li, Sha, Guo, Chongye, Li, Qian, Zhang, Xin, Li, Meng, Mi, Shuangli, 2021
The long noncoding RNA HOTAIRM1 controlled by AML1 enhances glucocorticoid resistance by activating RHOA/ROCK1 pathway through suppressing ARHGAP18., Liang, Liang, Gu, Wenbin, Li, Meng, Gao, Ran, Zhang, Xin, Guo, Chongye, Mi, Shuangli, 2021
Identification of Potential Key lncRNAs in the Context of Mouse Myeloid Differentiation by Systematic Transcriptomics Analysis., Lan, Yongqing, Li, Meng, Mi, Shuangli, 2021
Dietary Intervention With α-Amylase Inhibitor in White Kidney Beans Added Yogurt Modulated Gut Microbiota to Adjust Blood Glucose in Mice., Shenli Wang, Chongye Guo, Zhikai Xing, Meng Li, Haiying Yang, Yunting Zhang, Fazheng Ren, Lishui Chen, Shuangli Mi, 2021
Secretome of Activated Fibroblasts Induced by Exosomes for the Discovery of Biomarkers in Non-Small Cell Lung Cancer., Zhang, Jian, Fu, Bin, Li, Meng, Mi, Shuangli, 2021
miR-218-2 regulates cognitive functions in the hippocampus through complement component 3-dependent modulation of synaptic vesicle release., Lu, SiYao, Fu, ChongLei, Liang, Liang, Yang, Bo, Shen, Wei, Wang, QiuWen, Chen, Yun, Chen, YanFen, Liu, YaoNan, Zhu, Lin, Zhao, Jieqing, Shi, Wei, Mi, Shuangli, Yao, Jun, 2021
Tumor-derived circulating exosomal miR-342-5p and miR-574-5p as promising diagnostic biomarkers for early-stage Lung Adenocarcinoma., Han, Zhijun, Li, Yangyang, Zhang, Jian, Guo, Chongye, Li, Qian, Zhang, Xin, Lan, Yongqing, Gu, Wenbin, Xing, Zhikai, Liang, Liang, Li, Meng, Mi, Shuangli, 2020
A promising iPS-based single-cell cloning strategy revealing signatures of somatic mutations in heterogeneous normal cells., Miao, Xuexia, Li, Yueying, Zheng, Caihong, Wang, Lifei, Jin, Chen, Chen, Lei, Mi, Shuangli, Zhai, Weiwei, Wang, QianFei, Cai, Jun, 2020
Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice., Shen, Wei, Wang, QiuWen, Liu, YaoNan, Marchetto, Maria C, Linker, Sara, Lu, SiYao, Chen, Yun, Liu, Chuihong, Guo, Chongye, Xing, Zhikai, Shi, Wei, Kelsoe, John R, Alda, Martin, Wang, Hongwei, Zhong, Yi, Sui, SenFang, Zhao, Mei, Yang, Yiming, Mi, Shuangli, Cao, Liping, Gage, Fred H, Yao, Jun, 2020
RBUD: A New Functional Potential Analysis Approach for Whole Microbial Genome Shotgun Sequencing., Xing, Zhikai, Zhang, Yunting, Li, Meng, Guo, Chongye, Mi, Shuangli, 2020
植物益生元对肠道菌群的调节及对机体糖代谢吸收的影响., 郭翀晔, 邢志凯, 李蒙, 胡晓璐, 吴霞, 陈历水, 米双利, 2019
中药对肠道菌群的调节作用., 于岚, 邢志凯, 米双利, 吴霞, 2019
CRISPR interference-based specific and efficient gene inactivation in the brain (vol 21, pg 447, 2018)., Zheng, Yi, Shen, Wei, Zhang, Jian, Yang, Bo, Liu, YaoNan, Qi, Huihui, Yu, Xia, Lu, SiYao, Chen, Yun, Xu, YuZhou, Li, Yun, Gage, Fred H, Mi, Shuangli, Yao, Jun, 2018
CRISPR interference-based specific and efficient gene inactivation in the brain., Zheng, Yi, Shen, Wei, Zhang, Jian, Yang, Bo, Liu, YaoNan, Qi, Huihui, Yu, Xia, Lul, SiYao, Chen, Yun, Xu, YuZhou, Lp, Yun, Gage, Fred H, Mi, Shuangli, Yao, Jun, 2018
Early different downstream target of glucocorticoid receptor contributing to Glucocorticoids sensitivity in Kasumi-1 cells. (ASH meeting)., Mi Shuangli, 2016
Base-excision repair and beyond -A short summary attributed to scientific achievements of Tomas Lindahl, Nobel Prize Laureate in Chemistry 2015., Mi, Shuangli, Klungland, Arne, Yang, YunGui, 2016
Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function., Zhang, Jian, Li, Sha, Li, Lu, Li, Meng, Guo, Chongye, Yao, Jun, Mi, Shuangli, 2015
Circulating MicroRNAs as Biomarkers for Inflammatory Diseases., Shuangli Mi, Jian Zhang, Wei Zhang, R Stephanie Huang, 2013
孕期暴露因素与新生儿血管瘤发生的关联性研究., 王琳, 米双利, 陈杰, 刘芳, 李迎春, 郭彩虹, 张勇, 范钦颖, 2012
An eQTL-based method identifies CTTN and ZMAT3 as pemetrexed susceptibility markers., Wen, Yujia, Gamazon, Eric R, Bleibel, Wasim K, Wing, Claudia, Mi, Shuangli, McIlwee, Bridget E, Delaney, Shannon M, Duan, Shiwei, Im, Hae Kyung, Dolan, M Eileen, 2012
新生儿血管瘤发生的高危因素., 米双利, 2012
MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome., Wang, Qianfei, Wu, George, Mi, Shuangli, He, Fuhong, Wu, Jun, Dong, Jingfang, Luo, Roger T, Mattison, Ryan, Kaberlein, Joseph J, Prabhakar, Shyam, Ji, Hongkai, Thirman, Michael J, 2011
Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia., Mi, Shuangli, Li, Zejuan, Chen, Ping, He, Chunjiang, Cao, Donglin, Elkahloun, Abdel, Lu, Jun, Pelloso, Luis A, Wunderlich, Mark, Huang, Hao, Luo, Roger T, Sun, Miao, He, Miao, Neilly, Mary Beth, ZeleznikLe, Nancy J, Thirman, Michael J, Mulloy, James C, Liu, Paul P, Rowley, Janet D, Chen, Jianjun, 2010
Comprehensive analysis of the impact of SNPs and CNVs on human microRNAs and their regulatory genes., Duan, Shiwei, Mi, Shuangli, Zhang, Wei, Dolan, M Eileen, 2009
Consistent Deregulation of Gene Expression between Human and Murine MLL Rearrangement Leukemias., Li, Zejuan, Luo, Roger T, Mi, Shuangli, Sun, Miao, Chen, Ping, Bao, Jingyue, Neilly, Mary Beth, Jayathilaka, Nimanthi, Johnson, Deborah S, Wang, Lili, Lavau, Catherine, Zhang, Yanming, Tseng, Charles, Zhang, Xiuqing, Wang, Jian, Yu, Jun, Yang, Huanming, Wang, San Ming, Rowley, Janet D, Chen, Jianjun, Thirman, Michael J, 2009
Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity., Hartford, Christine M, Duan, Shiwei, Delaney, Shannon M, Mi, Shuangli, Kistner, Emily O, Lamba, Jatinder K, Huang, R Stephanie, Dolan, M Eileen, 2009
Candidate genes pharmacogenetics of anti-cancer agents., Mi Shuangli, 2009
Expression and alternative splicing of folate pathway genes in HapMap lymphoblastoid cell lines., Duan, Shiwei, Huang, R Stephanie, Zhang, Wei, Mi, Shuangli, Bleibel, Wasim K, Kistner, Emily O, Cox, Nancy J, Dolan, M Eileen, 2009
Distinct microRNA expression profiles in acute myeloid leukemia with common translocations., Li, Zejuan, Lu, Jun, Sun, Miao, Mi, Shuangli, Zhang, Hao, Luo, Roger T, Chen, Ping, Wang, Yungui, Yan, Ming, Qian, Zhijian, Neilly, Mary Beth, Jin, Jie, Zhang, Yanming, Bohlander, Stefan K, Zhang, DongEr, Larson, Richard A, Le Beau, Michelle M, Thirman, Michael J, Golub, Todd R, Rowley, Janet D, Chen, Jianjun, 2008
Recent patents on the identification and clinical application of microRNAs and target genes., Mi Shuangli, 2007
MicroRNA Expression Signatures Accurately Discriminate Acute Lymphoblastic Leukemia from Acute Myeloid Leukemia., Shuangli Mi PhD, Jun Lu PhD, Miao Sun MS, Zejuan Li PhD, Hao Zhang MS, Mary Beth Neilly MS,

Cancer Genomics Gene Expression Non-Coding Rna Epigenetics Pharmacogenomics Tumor Genetic Regulation Dna Repair Precision Medicine

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