Professor | Li Yuan | Asia Growth Partners

Name	Li Yuan
Contact Information	yuanli@gucas.ac.cn
Language ability	English, Chinese, Swedish
Province	Beijing

Name

Li Yuan

Contact Information

yuanli@gucas.ac.cn

Language ability

English, Chinese, Swedish

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	1995-01 to 2000-04 PhD: Karolinska Institute, Sweden
Work Experience	2009-07 to Present - University of Chinese Academy of Sciences - Professor, Doctoral Supervisor 2004-01 to 2009-06 - Karolinska Institute - Principal Investigator

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

1995-01 to 2000-04 PhD: Karolinska Institute, Sweden

Work Experience

2009-07 to Present - University of Chinese Academy of Sciences - Professor, Doctoral Supervisor
2004-01 to 2009-06 - Karolinska Institute - Principal Investigator

Areas of Focus	Mammalian Genetics and Development Signaling in Development
Publications	Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion., Fang G, Zhang D, Yin H, Zheng L, Bi X, Yuan L., 2014 Spatiotemporal association of DNAJB13 with the annulus during mouse sperm flagellum development., Guan J, Kinoshita M, Yuan L., 2009 Cohesin protein SMC1 is a centrosomal protein., Guan J, Ekwurtzel E, Kvist U, Yuan L., 2008 E2F1 deficiency impairs murine spermatogenesis and augments testicular degeneration in SCP3-nullizygous mice., Hoja MR, Liu JG, Mohammadieh M, Kvist U, Yuan L., 2004 Female germ cell aneuploidy and embryo death in mice lacking the meiosis-specific protein SCP3., Yuan L, Liu JG, Hoja MR, Wilbertz J, Nordqvist K, Hoog C., 2002 Loss of a Centrosomal Protein, Centlein, Promotes Cell Cycle Progression., Yang Ling, Zhang Ying, Yuan Li., 2019 Mechanistic insights into acephalic spermatozoa syndrome–associated mutations in the human SUN5 gene., Yongliang Shang, Jie Yan, Wenhao Tang, Chao Liu, Sai Xiao, Yueshuai Guo, Li Yuan, Liang Chen, Hui Jiang, Xuejiang Guo, Jie Qiao, Wei Li., 2018 Essential role for SUN5 in anchoring sperm head to the tail., Shang, Yongliang, Zhu, Fuxi, Wang, Lina, Ouyang, YingChun, Dong, MingZhe, Liu, Chao, Zhao, Haichao, Cui, Xiuhong, Ma, Dongyuan, Zhang, Zhiguo, Yang, Xiaoyu, Guo, Yueshuai, Liu, Feng, Yuan, Li, Gao, Fei, Guo, Xuejiang, Sun, QingYuan, Cao, Yunxia, Li, Wei., 2017 Centrosomal MCM7 strengthens the Cep68-VHL interaction and excessive MCM7 leads to centrosome splitting resulting from increase in Cep68 ubiquitination and proteasomal degradation., Kong, Lingjun, Yin, Huilong, Yuan, Li., 2017 Contribution of Genetic Polymorphisms and Haplotypes in DRD2 , BDNF , and Opioid Receptors to Heroin Dependence and Endophenotypes Among the Han Chinese., Gao Xuan, Wang Youxin, Lang Minglin, Yuan Li, Reece Albert Stuart, Wang Wei., 2017 Rootletin prevents Cep68 from VHL-mediated proteasomal degradation to maintain centrosome cohesion., Yin Huilong, Zheng Lu, Liu Weixiao, Zhang Dachuan, Li Wei, Yuan Li., 2017 Centlein, a novel microtubule-associated protein stabilizing microtubules and involved in neurite formation., Jing, Zhenli, Yin, Huilong, Wang, Pan, Gao, Juntao, Yuan, Li., 2016 Mutations in DNAJB13, Encoding an HSP40 Family Member, Cause Primary Ciliary Dyskinesia and Male Infertilit., YUAN LI., 2016 Positive correlation between the expression of hEag1 and HIF-1 alpha in breast cancers: an observational study., Lai, Qingxuan, Wang, Ting, Guo, Qingqing, Zhang, Yuxiang, Wang, Youxin, Yuan, Li, Ling, Rui, He, Yan, Wang, Wei., 2014 Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion., Fang, Guoliang, Zhang, Dachuan, Yin, Huilong, Zheng, Lu, Bi, Xiaolin, Yuan, Li., 2014 GST-β-catenin-His双标签融合蛋白的原核表达、纯化及鉴定., 尹会龙, 袁莉., 2012

Areas of Focus

Mammalian Genetics and Development
Signaling in Development

Publications

Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion., Fang G, Zhang D, Yin H, Zheng L, Bi X, Yuan L., 2014
Spatiotemporal association of DNAJB13 with the annulus during mouse sperm flagellum development., Guan J, Kinoshita M, Yuan L., 2009
Cohesin protein SMC1 is a centrosomal protein., Guan J, Ekwurtzel E, Kvist U, Yuan L., 2008
E2F1 deficiency impairs murine spermatogenesis and augments testicular degeneration in SCP3-nullizygous mice., Hoja MR, Liu JG, Mohammadieh M, Kvist U, Yuan L., 2004
Female germ cell aneuploidy and embryo death in mice lacking the meiosis-specific protein SCP3., Yuan L, Liu JG, Hoja MR, Wilbertz J, Nordqvist K, Hoog C., 2002
Loss of a Centrosomal Protein, Centlein, Promotes Cell Cycle Progression., Yang Ling, Zhang Ying, Yuan Li., 2019
Mechanistic insights into acephalic spermatozoa syndrome–associated mutations in the human SUN5 gene., Yongliang Shang, Jie Yan, Wenhao Tang, Chao Liu, Sai Xiao, Yueshuai Guo, Li Yuan, Liang Chen, Hui Jiang, Xuejiang Guo, Jie Qiao, Wei Li., 2018
Essential role for SUN5 in anchoring sperm head to the tail., Shang, Yongliang, Zhu, Fuxi, Wang, Lina, Ouyang, YingChun, Dong, MingZhe, Liu, Chao, Zhao, Haichao, Cui, Xiuhong, Ma, Dongyuan, Zhang, Zhiguo, Yang, Xiaoyu, Guo, Yueshuai, Liu, Feng, Yuan, Li, Gao, Fei, Guo, Xuejiang, Sun, QingYuan, Cao, Yunxia, Li, Wei., 2017
Centrosomal MCM7 strengthens the Cep68-VHL interaction and excessive MCM7 leads to centrosome splitting resulting from increase in Cep68 ubiquitination and proteasomal degradation., Kong, Lingjun, Yin, Huilong, Yuan, Li., 2017
Contribution of Genetic Polymorphisms and Haplotypes in DRD2 , BDNF , and Opioid Receptors to Heroin Dependence and Endophenotypes Among the Han Chinese., Gao Xuan, Wang Youxin, Lang Minglin, Yuan Li, Reece Albert Stuart, Wang Wei., 2017
Rootletin prevents Cep68 from VHL-mediated proteasomal degradation to maintain centrosome cohesion., Yin Huilong, Zheng Lu, Liu Weixiao, Zhang Dachuan, Li Wei, Yuan Li., 2017
Centlein, a novel microtubule-associated protein stabilizing microtubules and involved in neurite formation., Jing, Zhenli, Yin, Huilong, Wang, Pan, Gao, Juntao, Yuan, Li., 2016
Mutations in DNAJB13, Encoding an HSP40 Family Member, Cause Primary Ciliary Dyskinesia and Male Infertilit., YUAN LI., 2016
Positive correlation between the expression of hEag1 and HIF-1 alpha in breast cancers: an observational study., Lai, Qingxuan, Wang, Ting, Guo, Qingqing, Zhang, Yuxiang, Wang, Youxin, Yuan, Li, Ling, Rui, He, Yan, Wang, Wei., 2014
Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion., Fang, Guoliang, Zhang, Dachuan, Yin, Huilong, Zheng, Lu, Bi, Xiaolin, Yuan, Li., 2014
GST-β-catenin-His双标签融合蛋白的原核表达、纯化及鉴定., 尹会龙, 袁莉., 2012

Genetics Development Mammals Signaling Biochemistry Molecular Biology Cell Biology Research Spermatogenesis Centrosome

Jinsong Bian - Southern University of Science and Technology

Jin Tang Dong - Southern University of Science and Technology

Ning Jia - Southern University of Science and Technology

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