Professor | 袁莉 | 数字化转型顾问

Name	袁莉
Contact Information	yuanli@gucas.ac.cn
Language ability	英语, 中文, 瑞典语
Province	北京

Name

袁莉

Contact Information

yuanli@gucas.ac.cn

Language ability

英语, 中文, 瑞典语

Province

北京

University/Lab Affiliation and Title	中国科学院大学
Faculty	Medical School
Academic Background & Achievements	1995-01 至 2000-04 博士: 瑞典卡罗林斯卡研究院
Work Experience	2009-07 至今 - 中国科学院大学 - 教授，博士生导师 2004-01 至 2009-06 - 瑞典卡罗林斯卡研究院 - 主要研究员

University/Lab Affiliation and Title

中国科学院大学

Faculty

Medical School

Academic Background & Achievements

1995-01 至 2000-04 博士: 瑞典卡罗林斯卡研究院

Work Experience

2009-07 至今 - 中国科学院大学 - 教授，博士生导师
2004-01 至 2009-06 - 瑞典卡罗林斯卡研究院 - 主要研究员

Areas of Focus	哺乳动物的遗传与发育发育中的信号传导
Publications	Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion., Fang G, Zhang D, Yin H, Zheng L, Bi X, Yuan L., 2014 Spatiotemporal association of DNAJB13 with the annulus during mouse sperm flagellum development., Guan J, Kinoshita M, Yuan L., 2009 Cohesin protein SMC1 is a centrosomal protein., Guan J, Ekwurtzel E, Kvist U, Yuan L., 2008 E2F1 deficiency impairs murine spermatogenesis and augments testicular degeneration in SCP3-nullizygous mice., Hoja MR, Liu JG, Mohammadieh M, Kvist U, Yuan L., 2004 Female germ cell aneuploidy and embryo death in mice lacking the meiosis-specific protein SCP3., Yuan L, Liu JG, Hoja MR, Wilbertz J, Nordqvist K, Hoog C., 2002 Loss of a Centrosomal Protein, Centlein, Promotes Cell Cycle Progression., Yang Ling, Zhang Ying, Yuan Li., 2019 Mechanistic insights into acephalic spermatozoa syndrome–associated mutations in the human SUN5 gene., Yongliang Shang, Jie Yan, Wenhao Tang, Chao Liu, Sai Xiao, Yueshuai Guo, Li Yuan, Liang Chen, Hui Jiang, Xuejiang Guo, Jie Qiao, Wei Li., 2018 Essential role for SUN5 in anchoring sperm head to the tail., Shang, Yongliang, Zhu, Fuxi, Wang, Lina, Ouyang, YingChun, Dong, MingZhe, Liu, Chao, Zhao, Haichao, Cui, Xiuhong, Ma, Dongyuan, Zhang, Zhiguo, Yang, Xiaoyu, Guo, Yueshuai, Liu, Feng, Yuan, Li, Gao, Fei, Guo, Xuejiang, Sun, QingYuan, Cao, Yunxia, Li, Wei., 2017 Centrosomal MCM7 strengthens the Cep68-VHL interaction and excessive MCM7 leads to centrosome splitting resulting from increase in Cep68 ubiquitination and proteasomal degradation., Kong, Lingjun, Yin, Huilong, Yuan, Li., 2017 Contribution of Genetic Polymorphisms and Haplotypes in DRD2 , BDNF , and Opioid Receptors to Heroin Dependence and Endophenotypes Among the Han Chinese., Gao Xuan, Wang Youxin, Lang Minglin, Yuan Li, Reece Albert Stuart, Wang Wei., 2017 Rootletin prevents Cep68 from VHL-mediated proteasomal degradation to maintain centrosome cohesion., Yin Huilong, Zheng Lu, Liu Weixiao, Zhang Dachuan, Li Wei, Yuan Li., 2017 Centlein, a novel microtubule-associated protein stabilizing microtubules and involved in neurite formation., Jing, Zhenli, Yin, Huilong, Wang, Pan, Gao, Juntao, Yuan, Li., 2016 Mutations in DNAJB13, Encoding an HSP40 Family Member, Cause Primary Ciliary Dyskinesia and Male Infertilit., YUAN LI., 2016 Positive correlation between the expression of hEag1 and HIF-1 alpha in breast cancers: an observational study., Lai, Qingxuan, Wang, Ting, Guo, Qingqing, Zhang, Yuxiang, Wang, Youxin, Yuan, Li, Ling, Rui, He, Yan, Wang, Wei., 2014 Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion., Fang, Guoliang, Zhang, Dachuan, Yin, Huilong, Zheng, Lu, Bi, Xiaolin, Yuan, Li., 2014 GST-β-catenin-His双标签融合蛋白的原核表达、纯化及鉴定., 尹会龙, 袁莉., 2012

Areas of Focus

哺乳动物的遗传与发育
发育中的信号传导

Publications

Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion., Fang G, Zhang D, Yin H, Zheng L, Bi X, Yuan L., 2014
Spatiotemporal association of DNAJB13 with the annulus during mouse sperm flagellum development., Guan J, Kinoshita M, Yuan L., 2009
Cohesin protein SMC1 is a centrosomal protein., Guan J, Ekwurtzel E, Kvist U, Yuan L., 2008
E2F1 deficiency impairs murine spermatogenesis and augments testicular degeneration in SCP3-nullizygous mice., Hoja MR, Liu JG, Mohammadieh M, Kvist U, Yuan L., 2004
Female germ cell aneuploidy and embryo death in mice lacking the meiosis-specific protein SCP3., Yuan L, Liu JG, Hoja MR, Wilbertz J, Nordqvist K, Hoog C., 2002
Loss of a Centrosomal Protein, Centlein, Promotes Cell Cycle Progression., Yang Ling, Zhang Ying, Yuan Li., 2019
Mechanistic insights into acephalic spermatozoa syndrome–associated mutations in the human SUN5 gene., Yongliang Shang, Jie Yan, Wenhao Tang, Chao Liu, Sai Xiao, Yueshuai Guo, Li Yuan, Liang Chen, Hui Jiang, Xuejiang Guo, Jie Qiao, Wei Li., 2018
Essential role for SUN5 in anchoring sperm head to the tail., Shang, Yongliang, Zhu, Fuxi, Wang, Lina, Ouyang, YingChun, Dong, MingZhe, Liu, Chao, Zhao, Haichao, Cui, Xiuhong, Ma, Dongyuan, Zhang, Zhiguo, Yang, Xiaoyu, Guo, Yueshuai, Liu, Feng, Yuan, Li, Gao, Fei, Guo, Xuejiang, Sun, QingYuan, Cao, Yunxia, Li, Wei., 2017
Centrosomal MCM7 strengthens the Cep68-VHL interaction and excessive MCM7 leads to centrosome splitting resulting from increase in Cep68 ubiquitination and proteasomal degradation., Kong, Lingjun, Yin, Huilong, Yuan, Li., 2017
Contribution of Genetic Polymorphisms and Haplotypes in DRD2 , BDNF , and Opioid Receptors to Heroin Dependence and Endophenotypes Among the Han Chinese., Gao Xuan, Wang Youxin, Lang Minglin, Yuan Li, Reece Albert Stuart, Wang Wei., 2017
Rootletin prevents Cep68 from VHL-mediated proteasomal degradation to maintain centrosome cohesion., Yin Huilong, Zheng Lu, Liu Weixiao, Zhang Dachuan, Li Wei, Yuan Li., 2017
Centlein, a novel microtubule-associated protein stabilizing microtubules and involved in neurite formation., Jing, Zhenli, Yin, Huilong, Wang, Pan, Gao, Juntao, Yuan, Li., 2016
Mutations in DNAJB13, Encoding an HSP40 Family Member, Cause Primary Ciliary Dyskinesia and Male Infertilit., YUAN LI., 2016
Positive correlation between the expression of hEag1 and HIF-1 alpha in breast cancers: an observational study., Lai, Qingxuan, Wang, Ting, Guo, Qingqing, Zhang, Yuxiang, Wang, Youxin, Yuan, Li, Ling, Rui, He, Yan, Wang, Wei., 2014
Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion., Fang, Guoliang, Zhang, Dachuan, Yin, Huilong, Zheng, Lu, Bi, Xiaolin, Yuan, Li., 2014
GST-β-catenin-His双标签融合蛋白的原核表达、纯化及鉴定., 尹会龙, 袁莉., 2012

遗传学发育哺乳动物信号传导生物化学分子生物学细胞生物学研究精子发生中心体

董金堂 - 南方科技大学

贾宁 - 南方科技大学

季洋 - 南方科技大学

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