Professor | Yimeng Gao | Asia Growth Partners

Name	Yimeng Gao
Contact Information	gaoym@tongji.edu.cn
Language ability	English, Chinese
Province	Shanghai

Name

Yimeng Gao

Contact Information

gaoym@tongji.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	2011 - Bachelor's Degree: Ocean University of China 2017 - PhD: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences 2022 - Selected for Shanghai's 'Overseas High-Level Talent Introduction Plan'
Work Experience	2017-2022 - Yale University School of Medicine, Postdoctoral Research 2022-present - Tongji University, Distinguished Research Fellow under the 'Young Hundred Talents Plan' 2023-present - Tongji University Affiliated Oriental Hospital, Distinguished Research Fellow
Awards	2014: Cell Press China Paper of the Year 2017: Top Ten Medical Advances in China 2018: First Prize, Shanghai Science and Technology Award (Ranked 4th) 2019: James Hudson Brown - Alexander B. Coxe Fellowship at Yale University School of Medicine 2021: ASH Scholar Award from the American Society of Hematology

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

2011 - Bachelor's Degree: Ocean University of China
2017 - PhD: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
2022 - Selected for Shanghai's 'Overseas High-Level Talent Introduction Plan'

Work Experience

2017-2022 - Yale University School of Medicine, Postdoctoral Research
2022-present - Tongji University, Distinguished Research Fellow under the 'Young Hundred Talents Plan'
2023-present - Tongji University Affiliated Oriental Hospital, Distinguished Research Fellow

Awards

2014: Cell Press China Paper of the Year
2017: Top Ten Medical Advances in China
2018: First Prize, Shanghai Science and Technology Award (Ranked 4th)
2019: James Hudson Brown - Alexander B. Coxe Fellowship at Yale University School of Medicine
2021: ASH Scholar Award from the American Society of Hematology

Areas of Focus	Regulation of hematopoietic development Inflammatory response effects on blood regeneration and cellular aging Energy metabolism in the development of blood diseases Mechanisms of small molecule inhibitors in cancer immunotherapy
Publications	ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m(6)A modification-mediated RNA stability control, Gao Y, Zimmer JT, Vasic R, Liu C, Gbyli R, Zheng SJ, Patel A, Liu W, Qi Z, Li Y, Nelakanti R, Song Y, Biancon G, Xiao AZ, Slavoff S, Kibbey RG, Flavell RA, Simon MD, Tebaldi T, Li HB, Halene S, 2023 In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2, Gbyli R, Song Y, Liu W, Gao Y, Biancon G, Chandhok NS, Wang X, Fu X, Patel A, Sundaram R, Tebaldi T, Mamillapalli P, Zeidan AM, Flavell RA, Prebet T, Bindra RS, Halene S, 2022 Transcriptome-wide quantification of double-stranded RNAs in live mouse tissues by dsRIP-Seq, Gao Y, Chen S, Halene S, Tebaldi T, 2021 m(6)A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development, Gao Y, Vasic R, Song Y, Teng R, Liu C, Gbyli R, Biancon G, Nelakanti R, Lobben K, Kudo E, Liu W, Ardasheva A, Fu X, Wang X, Joshi P, Lee V, Dura B, Viero G, Iwasaki A, Fan R, Xiao A, Flavell RA, Li HB, Tebaldi T, Halene S, 2020 The role of RNA epigenetic modification in normal and malignant hematopoiesis, Vasic R, Gao Y, Liu C, Halene S, 2020 Distinct Gene Expression and Epigenetic Signatures in Hepatocyte-like Cells Produced by Different Strategies from the Same Donor, Gao Y, Zhang X, Zhang L, Cen J, Ni X, Liao X, Yang C, Li Y, Chen X, Zhang Z, Shu Y, Cheng X, Hay DC, Lai D, Pan G, Wei G, Hui L, 2017 Improved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytes, Shi XL, Gao Y, Yan Y, Ma H, Sun L, Huang P, Ni X, Zhang L, Zhao X, Ren H, Hu D, Zhou Y, Tian F, Ji Y, Cheng X, Pan G, Ding YT, Hui L, 2016 Direct reprogramming of human fibroblasts to functional and expandable hepatocytes, Huang P, Zhang L, Gao Y, He Z, Yao D, Wu Z, Cen J, Chen X, Liu C, Hu Y, Lai D, Hu Z, Chen L, Zhang Y, Cheng X, Ma X, Pan G, Wang X, Hui L*, 2014 生物人工肝研究进展, 高义萌, 孙露露, 惠利健, 2016 细胞命运转变——癌化和转分化的研究, 高义萌, 惠利健, 2014

Areas of Focus

Regulation of hematopoietic development
Inflammatory response effects on blood regeneration and cellular aging
Energy metabolism in the development of blood diseases
Mechanisms of small molecule inhibitors in cancer immunotherapy

Publications

ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m(6)A modification-mediated RNA stability control, Gao Y*, Zimmer JT, Vasic R, Liu C, Gbyli R, Zheng SJ, Patel A, Liu W, Qi Z, Li Y, Nelakanti R, Song Y, Biancon G, Xiao AZ, Slavoff S, Kibbey RG, Flavell RA, Simon MD, Tebaldi T, Li HB, Halene S*, 2023
In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2, Gbyli R, Song Y, Liu W, Gao Y, Biancon G, Chandhok NS, Wang X, Fu X, Patel A, Sundaram R, Tebaldi T, Mamillapalli P, Zeidan AM, Flavell RA, Prebet T, Bindra RS, Halene S*, 2022
Transcriptome-wide quantification of double-stranded RNAs in live mouse tissues by dsRIP-Seq, Gao Y, Chen S, Halene S, Tebaldi T*, 2021
m(6)A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development, Gao Y, Vasic R, Song Y, Teng R, Liu C, Gbyli R, Biancon G, Nelakanti R, Lobben K, Kudo E, Liu W, Ardasheva A, Fu X, Wang X, Joshi P, Lee V, Dura B, Viero G, Iwasaki A, Fan R, Xiao A, Flavell RA, Li HB, Tebaldi T, Halene S*, 2020
The role of RNA epigenetic modification in normal and malignant hematopoiesis, Vasic R, Gao Y, Liu C, Halene S*, 2020
Distinct Gene Expression and Epigenetic Signatures in Hepatocyte-like Cells Produced by Different Strategies from the Same Donor, Gao Y, Zhang X, Zhang L, Cen J, Ni X, Liao X, Yang C, Li Y, Chen X, Zhang Z, Shu Y, Cheng X, Hay DC, Lai D, Pan G, Wei G, Hui L*, 2017
Improved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytes, Shi XL, Gao Y, Yan Y, Ma H, Sun L, Huang P, Ni X, Zhang L, Zhao X, Ren H, Hu D, Zhou Y, Tian F, Ji Y, Cheng X, Pan G, Ding YT, Hui L*, 2016
Direct reprogramming of human fibroblasts to functional and expandable hepatocytes, Huang P, Zhang L, Gao Y, He Z, Yao D, Wu Z, Cen J, Chen X, Liu C, Hu Y, Lai D, Hu Z, Chen L, Zhang Y, Cheng X, Ma X, Pan G, Wang X, Hui L*, 2014
生物人工肝研究进展, 高义萌, 孙露露, 惠利健, 2016
细胞命运转变——癌化和转分化的研究, 高义萌, 惠利健, 2014

Hematopoietic Stem Cells Leukemia Myelodysplastic Syndromes Gene Mutations Rna Modifications M6A Energy Metabolism Glycolysis Oxidative Phosphorylation Cancer Immunotherapy

Wu Yuxuan - East China Normal University

Wu Yuxuan - East China Normal University

Yimeng Gao - Tongji University

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