Areas of Focus
- Epigenetic modifications in early embryonic development
- Epigenetic reprogramming in male and female pronuclei
- Molecular mechanisms of epigenetic modifications induced by nuclear transplantation
- Molecular function of Tet1 in induced reprogramming and its regulation of epigenetic reprogramming
- Proteomics and post-transcriptional modifications in early development
- Mechanisms of female gamete development and X-chromosome inactivation
Work Experience
- Since February 2014 - Tongji University: Research on epigenetic regulatory mechanisms in development, transdifferentiation, nuclear transplantation, and induced reprogramming
Academic Background & Achievements
- 2009 - Bachelor of Science: Shanghai Jiao Tong University
- 2014 - Doctor of Science: Peking Union Medical College, Beijing Institute of Life Sciences
- Published a cover article in Cell Stem Cell in 2013
- Published research in Nature
Publications
- Distinct features of H3K4me3 and H3K27me3 chromatin domains in pre-implantation embryos, Yawei Gao et al., 2016
- Replacement of Oct4 by Tet1 during iPSC Induction Reveals an Important Role of DNA Methylation and Hydroxymethylation in Reprogramming, Yawei Gao et al., 2013
- The Combination of Tet1 with Oct4 Generates High-Quality Mouse Induced Pluripotent Stem Cells (iPSCs), Yawei Gao et al., 2015
- Quality Control: H2A.X Links to Better iPSCs, Yawei Gao et al., 2014
- Xist Deficiency and Disorders of X-Inactivation in Rabbit Embryonic Stem Cells Can Be Rescued by Transcription-Factor-Mediated Conversion, Yawei Gao et al., 2014
- Identification of key factors conquering developmental arrest of somatic cell cloned embryos by combining embryo biopsy and single-cell sequencing, Yawei Gao et al., 2016
Awards
- 2017: Selected for the third batch of National Young Top-Notch Talent
- Recipient of Shanghai Morning Light Plan, Young Science Star Plan, and Youth Talent Support Project by the China Association for Science and Technology
