2006-2011 Doctorate: Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
2011-2013 - Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences - Associate Researcher
2013-present - Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences - Researcher
National Natural Science Award Second Prize
National Talent Program
Excellent Young Scientists Fund of the National Natural Science Foundation
Guangdong Special Support Program Leading Talent
Outstanding Youth Fund of Guangdong Natural Science Foundation
First Prize of Guangdong Science and Technology Award (2015)
First Prize of Guangzhou Science and Technology Award (2015)
Outstanding Achievement Award of the Chinese Academy of Sciences (Team)
Nanyue Innovation Award (2016)
Outstanding Young Scientist of the Chinese Academy of Sciences
Research
Molecular Mechanisms of Cell Fate Determination Epigenetic Regulation and Signal Transduction Computational Biology and Big Data Analysis Stem Cell Induction and Differentiation
The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity, Jiadong Liu, Mingwei Gao, Jiangping He, Kaixin Wu, Siyuan Lin, Lingmei Jin, Jiekai Chen, 2021
Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE, Jiangping He, Andrew P. Hutchins, Jiekai Chen, 2021
Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation, Feng-Liang Liu, Kaixin Wu, Jiaoyang Sun, Zilei Duan, Xiongzhi Quan, Guangming Wu, Yong-Tang Zheng, Jiekai Chen, 2021
COVID-19 immune features revealed by a large-scale single cell transcriptome atlas, Xianwen Ren, Wen Wen, Xiaoying Fan, Hongyang Wang, Bing Su, Zheng Zhang, Kun Qu, Xiaoqun Wang, Jiekai Chen, Ronghua Jin, Zemin Zhang, 2021
SETDB1-Mediated Cell Fate Transition between 2C- Like and Pluripotent States, Kaixin Wu, He Liu, Yaofeng Wang, Jiangping He, Jiekai Chen, 2020
YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways, Jiadong Liu, Mingwei Gao, Jiekai Chen, 2020
Perspectives on somatic reprogramming: spotlighting epigenetic regulation and cellular heterogeneity, Jiekai Chen, 2020
Epithelial-Mesenchymal Transition and Metabolic Switching in Cancer: Lessons From Somatic Cell Reprogramming, Xiaowei Lai, Qian Li, Fang Wu, Jiechun Lin, Jiekai Chen, Hui Zheng, Lin Guo, 2020
Concurrent binding to DNA and RNA facilitates the pluripotency reprogramming activity of Sox2, Linlin Hou, Yuanjie Wei, Jiekai Chen, Xichen Bao, Ralf Jauch, 2020
Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment, Jing Sun, Zhen Zhuang, Jian Zheng, Jiekai Chen, Yimin Li, Nanshan Zhong, David K. Meyerholz, Paul B. McCray, Jr., Stanley Perlman, Jincun Zhao, 2020
Transposable elements are regulated by context-specific patterns of chromatin marks in mouse embryonic stem cells, Jiangping He, Xiuling Fu, Meng Zhang, Jiekai Chen, Miguel A. Esteban, Andrew P. Hutchins, 2019
Failure to replicate the STAP cell phenomenon, Alejandro De Los Angeles, Francesco Ferrari, Jiekai Chen, Marti Borkent, Vladislav Krupalnik, Ernesto Lujan, Marius Wernig, Jacob H. Hanna, Konrad Hochedlinger, Duanqing Pei, Rudolf Jaenisch, Hongkui Deng, Stuart H. Orkin, Peter J. Park, George Q. Daley, 2015
Transcription factor Hoxb5 reprograms B cells into functional T lymphocytes, Mengyun Zhang, Yong Dong, Fangxiao Hu, Jiekai Chen, Aibin He, Bing Liu, Demin Wang, Yong-Guang Yang, Jinyong Wang, 2018
Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency, Shangtao Cao, Shengyong Yu, Dongwei Li, Jing Ye, Xuejie Yang, Guangjin Pan, Jiekai Chen, Jing Liu, Duanqing Pei, 2018
H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs, Jiekai Chen, He Liu, Jing Liu, Jing Qi, Bei Wei, Jiaqi Yang, Hanquan Liang, You Chen, 2013
Vitamin C modulates TET1 function during somatic cell reprogramming, Jiekai Chen, Lin Guo, Lei Zhang, Haoyu Wu, Jiaqi Yang, He Liu, 2013
