Mingquan Guo
Medical School
University of Chinese Academy of Sciences
Zhejiang
Language: Chinese, English
Contact
Marine Biomedicine Marine Biosecurity Natural Medicinal Chemistry Drug Activity Screening Mechanism Of Action Bioactive Compounds Pharmacology Biotechnology Biomedical Engineering Natural Products
Areas of Focus
  • Marine Biomedicine and Marine Biosecurity
  • Natural Medicinal Chemistry
  • Drug Activity Screening and Mechanism of Action
Work Experience
  • 2023-04~Present - Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences - Researcher Level 3
  • 2012-08~2023-03 - Wuhan Botanical Garden, Chinese Academy of Sciences - Researcher Level 3
  • 2007-10~2012-07 - University of Southern California - Research Assistant
  • 2006-03~2007-09 - Lawrence Berkeley National Laboratory, University of California - Postdoctoral Researcher
  • 2004-07~2006-02 - National Institutes of Health - Postdoctoral Researcher
  • 1998-09~2004-06 - Changchun Institute of Applied Chemistry, Chinese Academy of Sciences - PhD Student
Academic Background & Achievements
  • 1998-09--2004-06 PhD: Changchun Institute of Applied Chemistry, Chinese Academy of Sciences
Publications
  • Gymnema sylvestre extract ameliorated streptozotocin-induced hyperglycemia in T2DM rats via gut microbiota, 5th Author, 2023
  • Potential Antioxidative Components in Azadirachta indica Revealed by Bio-Affinity Ultrafiltration with SOD and XOD, 3rd Author, 2022
  • Potential hypoglycemic, hypolipidemic, and anti-inflammatory bioactive components in Nelumbo nucifera leaves explored by bioaffinity ultrafiltration with multiple targets, 11th Author, 2022
  • Flavonoids from Selaginella doederleinii Hieron and Their Antioxidant and Antiproliferative Activities, 11th Author, 2022
  • Potential Anti-aging Components From Moringa oleifera Leaves Explored by Affinity Ultrafiltration With Multiple Drug Targets, 11th Author, 2022
  • Potential Multifunctional Bioactive Compounds from Dysosma versipellis Explored by Bioaffinity Ultrafiltration-HPLC/MS with Topo I, Topo II COX-2 and ACE2, 11th Author, 2022
  • Potential multiple bioactive components from Sinopodophyllum hexandrum explored by affinity ultrafiltration with four drug targets, 11th Author, 2022
  • Screening and characterisation of potential antioxidant, hypoglycemic and hypolipidemic components revealed in Portulaca oleracea via multi-target affinity ultrafiltration LC-MS and molecular docking, 11th Author, 2022
  • Targeting Bacterial Membrane Proteins to Explore the Beneficial Effects of Natural Products: New Antibiotics against Drug Resistance, 11th Author, 2022
  • New Lignanamides with Antioxidant and Anti-Inflammatory Activities Screened Out and Identified from Warburgia ugandensis Combining Affinity Ultrafiltration LC-MS with SOD and XOD Enzymes, 11th Author, 2021
  • Phenolic Compounds from Carissa spinarum Are Characterized by Their Antioxidant, Anti-Inflammatory and Hepatoprotective Activities, 11th Author, 2021
  • Identification of Anti-Inflammatory and Anti-Proliferative Neolignanamides from Warburgia ugandensis Employing Multi-Target Affinity Ultrafiltration and LC-MS, 11th Author, 2021
  • Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by Warburgia ugandensis Extract through Mediating G(0)/G(1) Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation, 11th Author, 2021
  • Anti-Inflammatory Properties and Potential Bioactive Components from Moringa oleifera Leaves Revealed by Affinity Ultrafiltration LC-MS and Molecular Docking, 5th Author, 2021
  • Insecticidal Activities Against Odontotermes formosanus and Plutella xylostella and Corresponding Constituents of Tung Meal from Vernicia fordii, 11th Author, 2021
  • Antioxidant and Antiproliferative Potentials of Ficus glumosa and Its Bioactive Polyphenol Metabolites, 11th Author, 2021
  • Anticancer natural products, 4th Author, 2020
  • Hypoglycemic and hypolipidemic effects of Moringa oleifera leaves and their functional chemical constituents, 11th Author, 2020
  • Antioxidant, Anti-inflammatory Activities and Polyphenol Profile of Rhamnus prinoides, 11th Author, 2020
  • The Most Recent Advances in the Application of Nano-Structures/Nano-Materials for Single-Cell Sampling, 11th Author, 2020
  • A phase conversion headspace technique for the determination of anti-anaerobic activity of drug candidate based on the metabolic acidity change in culture medium, 11th Author, 2020
  • Screening for natural inhibitors of human topoisomerases from medicinal plants with bio-affinity ultrafiltration and LC-MS, 11th Author, 2020
  • Characterization of covalent protein modification by triclosan in vivo and in vitro via three-dimensional liquid chromatography-mass spectrometry: New insight into its adverse effects, 9th Author, 2020
  • Headspace gas chromatographic method for antimicrobial screening: Minimum inhibitory concentration determination, 11th Author, 2020
  • Comparing Three Different Extraction Techniques on Essential Oil Profiles of Cultivated and Wild Lotus (Nelumbo nucifera) Flower, 11th Author, 2020
  • Gas chromatographic analysis of naturally occurring cannabinoids: A review of literature published during the past decade, 2nd Author, 2020
  • In Vitro Antibacterial and Antiproliferative Potential of Echinops lanceolatus Mattf. (Asteraceae) and Identification of Potential Bioactive Compounds, 11th Author, 2020
  • Plukenetia huayllabambana Fruits: Analysis of Bioactive Compounds, Antibacterial Activity and Relative Action Mechanisms, 11th Author, 2020
  • 非洲白参的抗氧化活性及其化学成分研究, 5th Author, 2020
  • 响应面法优化飞龙掌血中总生物碱的提取工艺, 3rd Author, 2020
  • A review on the latest advances in extraction and analysis of artemisinin, 2nd Author, 2020
  • Antioxidant and Anti-Proliferative Properties of Hagenia abyssinica Roots and Their Potentially Active Components, 11th Author, 2020
  • Recent Advances in Molecular Docking for the Research and Discovery of Potential Marine Drugs, 11th Author, 2020
  • Plant-derived secondary metabolites as the main source of efflux pump inhibitors and methods for identification, 11th Author, 2020
  • Antiproliferative and Enzyme Docking Analysis of Engleromycin from Engleromyces goetzei, 11th Author, 2019
  • In-situ headspace analysis of metabolic carbon dioxide of aerobic bacteria for assessing antimicrobial activity of natural products, 11th Author, 2019
  • Integrated Proteomics, Biological Functional Assessments, and Metabolomics Reveal Toosendanin-Induced Hepatic Energy Metabolic Disorders, 8th Author, 2019
  • Volatile fingerprints and biomarkers of three representative kiwifruit cultivars obtained by headspace solid-phase microextraction gas chromatography mass spectrometry and chemometrics, 11th Author, 2019
  • Advances in MS Based Strategies for Probing Ligand-Target Interactions: Focus on Soft Ionization Mass Spectrometric Techniques, 11th Author, 2019
  • Comparative and chemometric analysis of correlations between the chemical fingerprints and anti-proliferative activities of ganoderic acids from three Ganoderma species, 11th Author, 2019
  • One-Pot Synthesis of Epirubicin-Capped Silver Nanoparticles and Their Anticancer Activity against Hep G2 Cells, 11th Author, 2019
  • Antioxidant and Anti-Inflammatory Activities of the Crude Extracts of Moringa oleifera from Kenya and Their Correlations with Flavonoids, 11th Author, 2019
  • Antioxidant and anti-inflammatory properties of flavonoids from lotus plumule, 11th Author, 2019
Awards
  • Chinese Academy of Sciences Wuhan Education Base Excellent Graduate Student Supervisor, First Prize, Ministry Level, 2022
  • Chinese Academy of Sciences Wuhan Branch Excellent Graduate Student Supervisor, Special Prize, Institute Level, 2020
  • Jilin Province Science and Technology Progress First Prize, Provincial Level, 2006
  • Chinese Academy of Sciences Procter & Gamble Excellent Doctoral Award, First Prize, Institute Level, 2004
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