2006-10 to 2010-03 Postdoctoral: Johns Hopkins University School of Medicine
2003-09 to 2006-06 PhD: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
2020-08 to Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Deputy Director, Director of the Neuropsychiatric Disease Research Center
2016-10 to Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Group Leader
2013-10 to Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher
2010-04 to Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Associate Researcher
2006-10 to 2010-03 - Johns Hopkins University School of Medicine - Postdoctoral
2003-09 to 2006-06 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - PhD Student
Innovation Talent Promotion Plan Young and Middle-aged Science and Technology Innovation Leading Talent (2019)
National Hundred, Thousand, and Ten Thousand Talent Project (2019)
American Heart Association Postdoctoral Fellowship (2007)
Research
Ion Channel Pharmacology and Drug Development Discovery and New Applications of Novel Ion Channels Viral Ion Channels
Direct Identification of Complex Glycans via a Highly Sensitive Engineered Nanopore, Zhaobing Gao, 2024
Characterization of the role of TMEM175 in an in vitro lysosomal H+ fluxes model, Zhaobing Gao, 2023
Extracellular vesicles mediate antibody-resistant transmission of SARS-CoV-2, Zhaobing Gao, 2023
Physiological and Pathological Functions of TRPM7 Channel and Its Small-molecule Modulators, Zhaobing Gao, 2023
Ligand activation mechanisms of human KCNQ2 channel, Zhaobing Gao, 2023
Disruption of ER ion homeostasis maintained by an ER anion channel CLCC1 contributes to ALS-like pathologies, Zhaobing Gao, 2023
Development of SV2A Ligands for Epilepsy Treatment: A Review of Levetiracetam, Brivaracetam, and Padsevonil, Zhaobing Gao, 2023
Mapping the Acetylamino and Carboxyl Groups on Glycans by Engineered β-Hemolysin Nanopores, Zhaobing Gao, 2023
Naphthylisoquinoline alkaloids, a new structural template inhibitor of Nav1.7 sodium channel, Zhaobing Gao, 2023
Discovery of selective NaV1.8 inhibitors based on 5-chloro-2-(4,4-difluoroazepan-1-yl)-6-methyl nicotinamide scaffold for the treatment of pain, Zhaobing Gao, 2023
Why is the SARS-CoV-2 Omicron variant milder?, Zhaobing Gao, 2022
Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates, Zhaobing Gao, 2022
SCN8A epileptic encephalopathy mutations display a gain-of-function phenotype and divergent sensitivity to antiepileptic drugs, Zhaobing Gao, 2022
Multiscale Co-reconstruction of Lung Architectures and Inhalable Materials Spatial Distribution, Zhaobing Gao, 2021
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target, Zhaobing Gao, 2021
Sanguinarine is an agonist of TRPA1 channel, Zhaobing Gao, 2021
An electric-field-responsive paramagnetic contrast agent enhances the visualization of epileptic foci in mouse models of drug-resistant epilepsy, Zhaobing Gao, 2021
Discovery of HN37 as a Potent and Chemically Stable Antiepileptic Drug Candidate, Zhaobing Gao, 2021
Identification of 2-substituted pyrrolo1,2-bpyridazine derivatives as new PARP-1 inhibitors, Zhaobing Gao, 2021
CCT128930 is a novel and potent antagonist of TRPM7 channel, Zhaobing Gao, 2021
Discovery of aryl sulfonamide-selective Nav1.7 inhibitors with a highly hydrophobic ethanoanthracene core, Zhaobing Gao, 2020
Antiepileptic geissoschizine methyl ether is an inhibitor of multiple neuronal channels, Zhaobing Gao, 2020
Inhibitory effects of lappaconitine on the neuronal isoforms of voltage-gated sodium channels, Zhaobing Gao, 2019
Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models, Zhaobing Gao, 2019
A Small-Molecule Compound Selectively Activates K2P Channel TASK-3 by Acting at Two Distant Clusters of Residues, Zhaobing Gao, 2019
Discovery of Novel Retigabine Derivatives as Potent KCNQ4 and KCNQ5 Channel Agonists with Improved Specificity, Zhaobing Gao, 2019
High-resolution mapping of brain vasculature and its impairment in the hippocampus of Alzheimer’s disease mice, Zhaobing Gao, 2019
靶向TRPA1通道治疗有机磷导致的神经损伤, Zhaobing Gao, 2018
A Statistical Thermodynamic Model for Ligands Interacting With Ion Channels: Theoretical Model and Experimental Validation of the KCNQ2 Channel, Zhaobing Gao, 2018
The synthesis and antistaphylococcal activity of N-sulfonaminoethyloxime derivatives of dehydroabietic acid, Zhaobing Gao, 2018
Succinate-acetate permease from Citrobacter koseri is an anion channel that unidirectionally translocates acetate, Zhaobing Gao, 2018
Enhancing inactivation rather than reducing activation of Nav1.7 channels by a clinically effective analgesic CNV1014802, Zhaobing Gao, 2018
CNV1014802 Rescues the Paroxysmal Extreme Pain Disorders Nav1.7 Mutants by Restoring Impaired Inactivation, Zhaobing Gao, 2017
Label-free brainwide visualization of senile plaque using cryo-micro-optical sectioning tomography, Zhaobing Gao, 2017
The synthesis and antistaphylococcal activity of dehydroabietic acid derivatives: modifications at C12 and C7, Zhaobing Gao, 2017
Two novel C18-diterpenoid alkaloids, sinomontadine with an unprecedented seven-membered ring A and chloride-containing sinomontanine N from Aconitum sinomontanum, Zhaobing Gao, 2017
Discovery of NAV1.7 Modulators from Marketed Drugs using High throuthput Automated Electrophysiological System Ionworks Barracuda, Zhaobing Gao, 2017
Voltage- to Ligand-Gated Switch in Voltage-Gated Potassium Channels, Zhaobing Gao, 2017
MLKL forms cation channels, Zhaobing Gao, 2016
Identification and Evaluation of Antiepileptic Activity of C-21 Steroidal Glycosides from the Roots of Cynanchum wilfordii, Zhaobing Gao, 2016
Development of Novel Alkoxyisoxazoles as Sigma-1 Receptor Antagonists with Antinociceptive Efficacy, Zhaobing Gao, 2016
Computer-Aided Drug Discovery and Design Targeting Ion Channels, Zhaobing Gao, 2016
Ion channels research in the post-genomic era, Zhaobing Gao, 2016
Grafting voltage and pharmacological sensitivity in potassium channels, Zhaobing Gao, 2016
Novel KCNQ2 channel activators discovered using fluorescence-based and automated patch-clamp-based high-throughput screening techniques, Zhaobing Gao
Keywords
Ion ChannelsPharmacologyDrug DevelopmentNovel Ion ChannelsApplicationsViral Ion ChannelsResearchNeuropsychiatric DiseasesElectrophysiologyMolecular Biology
