Professor | Chunsheng Han | Asia Growth Partners

Name	Chunsheng Han
Contact Information	hancs@ioz.ac.cn
Language ability	English, Chinese
Province	Beijing

Name

Chunsheng Han

Contact Information

hancs@ioz.ac.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	1993-09 to 2000-05 Ph.D. in Biochemistry: University of Missouri 1990-09 to 1993-05 Master's in Reproductive Physiology: State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences 1986-09 to 1990-05 Bachelor's in Genetics: Department of Bioengineering, Fudan University
Work Experience	2003-12 to Present - Institute of Zoology, Chinese Academy of Sciences - Researcher 2000-09 to 2013-11 - Lexicon Pharmaceuticals, USA - Senior Bioinformatics Scientist

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

1993-09 to 2000-05 Ph.D. in Biochemistry: University of Missouri
1990-09 to 1993-05 Master's in Reproductive Physiology: State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences
1986-09 to 1990-05 Bachelor's in Genetics: Department of Bioengineering, Fudan University

Work Experience

2003-12 to Present - Institute of Zoology, Chinese Academy of Sciences - Researcher
2000-09 to 2013-11 - Lexicon Pharmaceuticals, USA - Senior Bioinformatics Scientist

Areas of Focus	Spermatogonial Stem Cells (SSCs) proliferation, differentiation (meiosis), and dedifferentiation (reprogramming) Epigenetic regulation mechanisms of spermatogenesis
Publications	In vivo functions of miRNAs in mammalian spermatogenesis, Chen, Jian, Han, Chunsheng, 2023 Abnormal chromatin remodeling caused by ARID1A deletion leads to malformation of the dentate gyrus, Liu, PeiPei, Lu, ShiPing, Li, Xiao, Tang, GangBin, Liu, Xiao, Dai, ShangKun, Jiao, LinFei, Lin, XiWen, Li, XingGuo, Hu, Baoyang, Jiao, Jianwei, Teng, ZhaoQian, Han, ChunSheng, 刘长梅, 2023 A CRISPR/Cas9-based kinome screen identifies ErbB signaling as a new regulator of human naïve pluripotency and totipotency, 李佳宇, 韩春生, 2023 RBFOX2 缺失抑制雄性小鼠的减数分裂起始, 闫琳, 陈建, 宁岩, 韩春生, 2023 Metabolic dysregulation in patients with premature ovarian insufficiency revealed by integrated transcriptomic, methylomic and metabolomic analyses, Lu, Cuiling, Qin, Caimeng, Fu, Zheng, Wang, Lina, Yi, Yanxiao, Xin, Mingwei, Zhen, Xiumei, Han, Chunsheng, 2022 MicroRNA-202 safeguards meiotic progression by preventing premature SEPARASE-mediated REC8 cleavage, Chen, Jian, Gao, Chenxu, Luo, Mengcheng, Zheng, Chunwei, Lin, Xiwen, Ning, Yan, Ma, Longfei, He, Wei, Xie, Dan, Liu, Kui, Hong, Kai, Han, Chunsheng, 2022 Identification and characterization of BEND2 as a key regulator of meiosis during mouse spermatogenesis, Ma, Longfei, Xie, Dan, Luo, Mengcheng, Lin, Xiwen, Nie, Hengyu, Chen, Jian, Gao, Chenxu, Duo, Shuguang, Han, Chunsheng, 2022 The male germline-specific protein MAPS is indispensable for pachynema progression and fertility, Li, Miao, Zheng, Jiahuan, Li, Gaopeng, Lin, Zexiong, Li, Dongliang, Liu, Dongteng, Feng, Haiwei, Cao, Dandan, Ng, Ernest H Y, Li, Raymond H W, Han, Chunsheng, Yeung, William S B, Chow, Louise T, Wang, Hengbin, Liu, Kui, 2021 PRMT5 Is Involved in Spermatogonial Stem Cells Maintenance by Regulating Plzf Expression via Modulation of Lysine Histone Modifications, Dong, Fangfang, Chen, Min, Chen, Min, Jiang, Lin, Shen, Zhiming, Ma, Longfei, Han, Chunsheng, Guo, Xudong, Gao, Fei, 2021 The microRNA miR-202 prevents precocious spermatogonial differentiation and meiotic initiation during mouse spermatogenesis, Chen, Jian, Gao, Chenxu, Lin, Xiwen, Ning, Yan, He, Wei, Zheng, Chunwei, Zhang, Daoqin, Yan, Lin, Jiang, Binjie, Zhao, Yuting, Hossen, Md Alim, Han, Chunsheng, 2021

Areas of Focus

Spermatogonial Stem Cells (SSCs) proliferation, differentiation (meiosis), and dedifferentiation (reprogramming)
Epigenetic regulation mechanisms of spermatogenesis

Publications

In vivo functions of miRNAs in mammalian spermatogenesis, Chen, Jian, Han, Chunsheng, 2023
Abnormal chromatin remodeling caused by ARID1A deletion leads to malformation of the dentate gyrus, Liu, PeiPei, Lu, ShiPing, Li, Xiao, Tang, GangBin, Liu, Xiao, Dai, ShangKun, Jiao, LinFei, Lin, XiWen, Li, XingGuo, Hu, Baoyang, Jiao, Jianwei, Teng, ZhaoQian, Han, ChunSheng, 刘长梅, 2023
A CRISPR/Cas9-based kinome screen identifies ErbB signaling as a new regulator of human naïve pluripotency and totipotency, 李佳宇, 韩春生, 2023
RBFOX2 缺失抑制雄性小鼠的减数分裂起始, 闫琳, 陈建, 宁岩, 韩春生, 2023
Metabolic dysregulation in patients with premature ovarian insufficiency revealed by integrated transcriptomic, methylomic and metabolomic analyses, Lu, Cuiling, Qin, Caimeng, Fu, Zheng, Wang, Lina, Yi, Yanxiao, Xin, Mingwei, Zhen, Xiumei, Han, Chunsheng, 2022
MicroRNA-202 safeguards meiotic progression by preventing premature SEPARASE-mediated REC8 cleavage, Chen, Jian, Gao, Chenxu, Luo, Mengcheng, Zheng, Chunwei, Lin, Xiwen, Ning, Yan, Ma, Longfei, He, Wei, Xie, Dan, Liu, Kui, Hong, Kai, Han, Chunsheng, 2022
Identification and characterization of BEND2 as a key regulator of meiosis during mouse spermatogenesis, Ma, Longfei, Xie, Dan, Luo, Mengcheng, Lin, Xiwen, Nie, Hengyu, Chen, Jian, Gao, Chenxu, Duo, Shuguang, Han, Chunsheng, 2022
The male germline-specific protein MAPS is indispensable for pachynema progression and fertility, Li, Miao, Zheng, Jiahuan, Li, Gaopeng, Lin, Zexiong, Li, Dongliang, Liu, Dongteng, Feng, Haiwei, Cao, Dandan, Ng, Ernest H Y, Li, Raymond H W, Han, Chunsheng, Yeung, William S B, Chow, Louise T, Wang, Hengbin, Liu, Kui, 2021
PRMT5 Is Involved in Spermatogonial Stem Cells Maintenance by Regulating Plzf Expression via Modulation of Lysine Histone Modifications, Dong, Fangfang, Chen, Min, Chen, Min, Jiang, Lin, Shen, Zhiming, Ma, Longfei, Han, Chunsheng, Guo, Xudong, Gao, Fei, 2021
The microRNA miR-202 prevents precocious spermatogonial differentiation and meiotic initiation during mouse spermatogenesis, Chen, Jian, Gao, Chenxu, Lin, Xiwen, Ning, Yan, He, Wei, Zheng, Chunwei, Zhang, Daoqin, Yan, Lin, Jiang, Binjie, Zhao, Yuting, Hossen, Md Alim, Han, Chunsheng, 2021

Spermatogonial Stem Cells Proliferation Differentiation Meiosis Dedifferentiation Reprogramming Epigenetic Regulation Spermatogenesis Stem Cells

Chunsheng Han - University of Chinese Academy of Sciences

Zheqiong Yang - Wuhan University

Baoyang Hu - University of Chinese Academy of Sciences

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