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Chunsheng Han
Medical School
University of Chinese Academy of Sciences
Beijing
Language: English, Chinese
Contact
Spermatogonial Stem Cells Proliferation Differentiation Meiosis Dedifferentiation Reprogramming Epigenetic Regulation Spermatogenesis Stem Cells
Areas of Focus
  • Spermatogonial Stem Cells (SSCs) proliferation, differentiation (meiosis), and dedifferentiation (reprogramming)
  • Epigenetic regulation mechanisms of spermatogenesis
Work Experience
  • 2003-12 to Present - Institute of Zoology, Chinese Academy of Sciences - Researcher
  • 2000-09 to 2013-11 - Lexicon Pharmaceuticals, USA - Senior Bioinformatics Scientist
Academic Background & Achievements
  • 1993-09 to 2000-05 Ph.D. in Biochemistry: University of Missouri
  • 1990-09 to 1993-05 Master's in Reproductive Physiology: State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences
  • 1986-09 to 1990-05 Bachelor's in Genetics: Department of Bioengineering, Fudan University
Publications
  • In vivo functions of miRNAs in mammalian spermatogenesis, Chen, Jian, Han, Chunsheng, 2023
  • Abnormal chromatin remodeling caused by ARID1A deletion leads to malformation of the dentate gyrus, Liu, PeiPei, Lu, ShiPing, Li, Xiao, Tang, GangBin, Liu, Xiao, Dai, ShangKun, Jiao, LinFei, Lin, XiWen, Li, XingGuo, Hu, Baoyang, Jiao, Jianwei, Teng, ZhaoQian, Han, ChunSheng, 刘长梅, 2023
  • A CRISPR/Cas9-based kinome screen identifies ErbB signaling as a new regulator of human naïve pluripotency and totipotency, 李佳宇, 韩春生, 2023
  • RBFOX2 缺失抑制雄性小鼠的减数分裂起始, 闫琳, 陈建, 宁岩, 韩春生, 2023
  • Metabolic dysregulation in patients with premature ovarian insufficiency revealed by integrated transcriptomic, methylomic and metabolomic analyses, Lu, Cuiling, Qin, Caimeng, Fu, Zheng, Wang, Lina, Yi, Yanxiao, Xin, Mingwei, Zhen, Xiumei, Han, Chunsheng, 2022
  • MicroRNA-202 safeguards meiotic progression by preventing premature SEPARASE-mediated REC8 cleavage, Chen, Jian, Gao, Chenxu, Luo, Mengcheng, Zheng, Chunwei, Lin, Xiwen, Ning, Yan, Ma, Longfei, He, Wei, Xie, Dan, Liu, Kui, Hong, Kai, Han, Chunsheng, 2022
  • Identification and characterization of BEND2 as a key regulator of meiosis during mouse spermatogenesis, Ma, Longfei, Xie, Dan, Luo, Mengcheng, Lin, Xiwen, Nie, Hengyu, Chen, Jian, Gao, Chenxu, Duo, Shuguang, Han, Chunsheng, 2022
  • The male germline-specific protein MAPS is indispensable for pachynema progression and fertility, Li, Miao, Zheng, Jiahuan, Li, Gaopeng, Lin, Zexiong, Li, Dongliang, Liu, Dongteng, Feng, Haiwei, Cao, Dandan, Ng, Ernest H Y, Li, Raymond H W, Han, Chunsheng, Yeung, William S B, Chow, Louise T, Wang, Hengbin, Liu, Kui, 2021
  • PRMT5 Is Involved in Spermatogonial Stem Cells Maintenance by Regulating Plzf Expression via Modulation of Lysine Histone Modifications, Dong, Fangfang, Chen, Min, Chen, Min, Jiang, Lin, Shen, Zhiming, Ma, Longfei, Han, Chunsheng, Guo, Xudong, Gao, Fei, 2021
  • The microRNA miR-202 prevents precocious spermatogonial differentiation and meiotic initiation during mouse spermatogenesis, Chen, Jian, Gao, Chenxu, Lin, Xiwen, Ning, Yan, He, Wei, Zheng, Chunwei, Zhang, Daoqin, Yan, Lin, Jiang, Binjie, Zhao, Yuting, Hossen, Md Alim, Han, Chunsheng, 2021
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