Professor | Huang Zhong | Asia Growth Partners

Name	Huang Zhong
Contact Information	huangzhong@ips.ac.cn
Language ability	Chinese, English
Province	Shanghai

Name

Huang Zhong

Contact Information

huangzhong@ips.ac.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	1991-09 to 1997-06 PhD: China Agricultural University 1987-09 to 1991-06 Bachelor's Degree: China Agricultural University
Work Experience	2009-01 to Present - Shanghai Pasteur Institute, Chinese Academy of Sciences - Researcher, Group Leader 2005-09 to 2008-12 - Arizona State University - Assistant Research Professor 2002-09 to 2005-09 - Arizona State University - Senior Research Associate 1998-02 to 2002-09 - Boyce Thompson Institute, Cornell University - Postdoctoral Researcher
Awards	Shanghai Outstanding Technical Leader (2015) Chinese Academy of Sciences **** Selected (2010)

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

1991-09 to 1997-06 PhD: China Agricultural University
1987-09 to 1991-06 Bachelor's Degree: China Agricultural University

Work Experience

2009-01 to Present - Shanghai Pasteur Institute, Chinese Academy of Sciences - Researcher, Group Leader
2005-09 to 2008-12 - Arizona State University - Assistant Research Professor
2002-09 to 2005-09 - Arizona State University - Senior Research Associate
1998-02 to 2002-09 - Boyce Thompson Institute, Cornell University - Postdoctoral Researcher

Awards

Shanghai Outstanding Technical Leader (2015)
Chinese Academy of Sciences **** Selected (2010)

Areas of Focus	Development of vaccines and antiviral strategies for important viral diseases (Hand, Foot, and Mouth Disease, Hepatitis C, Norovirus infection, etc.) Novel genetic engineering vaccines and therapeutic monoclonal antibodies
Publications	High-yield production of recombinant virus-like particles of enterovirus 71 in Pichia pastoris and their protective efficacy against oral viral challenge in mice, Zhang C, Ku Z, Liu Q, Wang X, Chen T, Ye X, Li D, Jin X, Huang Z., 2015 Towards broadly protective polyvalent vaccines against hand, foot and mouth disease, Liu Q, Tong X, Huang Z., 2015 Phylogenetic analysis of the major causative agents of hand, foot and mouth disease in Suzhou City, Jiangsu Province, China, in 2012-2013, Zhang C, Zhu R, Yang Y, Chi Y, Yin J, Tang X, Yu L, Zhang C, Huang Z, Zhou D., 2015 Fighting Ebola with ZMapp: spotlight on plant-made antibody, Zhang Y, Li D, Huang Z., 2014 A virus-like particle based bivalent vaccine confers dual protection against enterovirus 71 and coxsackievirus A16 infections in mice, Ku Z, Liu Q, Ye X, Cai Y, Wang X, Shi J, Li D, Jin X, An W, Huang Z., 2014 A combination vaccine comprising of inactivated enterovirus 71 and coxsackievirus A16 elicits balanced protective immunity against both viruses, Cai Y, Ku Z, Liu Q, Leng Q, Huang Z., 2014 A murine model of coxsackievirus A16 infection for anti-viral evaluation, Liu Q, Shi J, Huang X, Liu F, Cai Y, Lan K, Huang Z., 2014 The molecule of DC-SIGN captures enterovirus 71 and confers dendritic cell-mediated viral trans-infection, Ren X, Ma L, Liu Q, Li C, Huang Z, Wu L, Xiong S, Wang J, Wang H., 2014 Chimeric virus-like particle vaccines displaying conserved enterovirus 71 epitopes elicit protective neutralizing antibodies in mice through divergent mechanisms, Ye X, Ku Z, Liu Q, Wang X, Shi J, Zhang Y, Kong L, Cong Y, Huang Z., 2014 Identification of conserved neutralizing linear epitopes within the VP1 protein of coxsackievirus A16, Shi J, Huang X, Liu Q, Huang Z., 2013 Active immunization with a coxsackievirus A16 experimental inactivated vaccine induces neutralizing antibodies and protects mice against lethal infection, Cai Y, Liu Q, Huang X, Li D, Ku Z, Zhang Y, Huang Z., 2013 Neutralizing antibodies induced by recombinant virus-like particles of enterovirus 71 genotype C4 inhibit infection at pre- and post-attachment steps, Ku Z, Ye X, Huang X, Cai Y, Liu Q, Li Y, Su Z, Huang Z., 2013 Characterization of enterovirus 71 capsids using subunit protein-specific polyclonal antibodies, Liu Q, Huang X, Ku Z, Wang T, Liu F, Cai Y, Li D, Leng Q, Huang Z., 2013 A virus-like particle vaccine for coxsackievirus A16 potently elicits neutralizing antibodies that protect mice against lethal challenge, Liu Q, Yan K, Feng Y, Huang X, Ku Z, Cai Y, Liu F, Shi J, Huang Z., 2012 Development of murine monoclonal antibodies with potent neutralization effects on enterovirus 71, Ku Z, Shi J, Liu Q, Huang Z., 2012 Construction and characterization of an infectious clone of coxsackievirus A16, Liu F, Liu Q, Cai Y, Leng Q, Huang Z., 2011 Detection, characterization and quantitation of coxsackievirus A16 using polyclonal antibodies against recombinant capsid subunit proteins, Liu Q, Ku Z, Cai Y, Sun B, Leng Q, Huang Z., 2011 Single-Particle Tracking of Hepatitis B Virus-like Vesicle Entry into Cells, Hao X, Shang X, Wu J, Shan Y, Cai M, Jiang J, Huang Z, Tang Z, Wang H., 2011 Expression of VP0 protein of enterovirus 71 in E.coli and generation of corresponding polyclonal antibodies, Feng Y, Liu Q, Ku Z, Wen J, Shan H, Huang Z., 2011

Areas of Focus

Development of vaccines and antiviral strategies for important viral diseases (Hand, Foot, and Mouth Disease, Hepatitis C, Norovirus infection, etc.)
Novel genetic engineering vaccines and therapeutic monoclonal antibodies

Publications

High-yield production of recombinant virus-like particles of enterovirus 71 in Pichia pastoris and their protective efficacy against oral viral challenge in mice, Zhang C, Ku Z, Liu Q, Wang X, Chen T, Ye X, Li D, Jin X, Huang Z., 2015
Towards broadly protective polyvalent vaccines against hand, foot and mouth disease, Liu Q, Tong X, Huang Z., 2015
Phylogenetic analysis of the major causative agents of hand, foot and mouth disease in Suzhou City, Jiangsu Province, China, in 2012-2013, Zhang C, Zhu R, Yang Y, Chi Y, Yin J, Tang X, Yu L, Zhang C, Huang Z, Zhou D., 2015
Fighting Ebola with ZMapp: spotlight on plant-made antibody, Zhang Y, Li D, Huang Z., 2014
A virus-like particle based bivalent vaccine confers dual protection against enterovirus 71 and coxsackievirus A16 infections in mice, Ku Z, Liu Q, Ye X, Cai Y, Wang X, Shi J, Li D, Jin X, An W, Huang Z., 2014
A combination vaccine comprising of inactivated enterovirus 71 and coxsackievirus A16 elicits balanced protective immunity against both viruses, Cai Y, Ku Z, Liu Q, Leng Q, Huang Z., 2014
A murine model of coxsackievirus A16 infection for anti-viral evaluation, Liu Q, Shi J, Huang X, Liu F, Cai Y, Lan K, Huang Z., 2014
The molecule of DC-SIGN captures enterovirus 71 and confers dendritic cell-mediated viral trans-infection, Ren X, Ma L, Liu Q, Li C, Huang Z, Wu L, Xiong S, Wang J, Wang H., 2014
Chimeric virus-like particle vaccines displaying conserved enterovirus 71 epitopes elicit protective neutralizing antibodies in mice through divergent mechanisms, Ye X, Ku Z, Liu Q, Wang X, Shi J, Zhang Y, Kong L, Cong Y, Huang Z., 2014
Identification of conserved neutralizing linear epitopes within the VP1 protein of coxsackievirus A16, Shi J, Huang X, Liu Q, Huang Z., 2013
Active immunization with a coxsackievirus A16 experimental inactivated vaccine induces neutralizing antibodies and protects mice against lethal infection, Cai Y, Liu Q, Huang X, Li D, Ku Z, Zhang Y, Huang Z., 2013
Neutralizing antibodies induced by recombinant virus-like particles of enterovirus 71 genotype C4 inhibit infection at pre- and post-attachment steps, Ku Z, Ye X, Huang X, Cai Y, Liu Q, Li Y, Su Z, Huang Z., 2013
Characterization of enterovirus 71 capsids using subunit protein-specific polyclonal antibodies, Liu Q, Huang X, Ku Z, Wang T, Liu F, Cai Y, Li D, Leng Q, Huang Z., 2013
A virus-like particle vaccine for coxsackievirus A16 potently elicits neutralizing antibodies that protect mice against lethal challenge, Liu Q, Yan K, Feng Y, Huang X, Ku Z, Cai Y, Liu F, Shi J, Huang Z., 2012
Development of murine monoclonal antibodies with potent neutralization effects on enterovirus 71, Ku Z, Shi J, Liu Q, Huang Z., 2012
Construction and characterization of an infectious clone of coxsackievirus A16, Liu F, Liu Q, Cai Y, Leng Q, Huang Z., 2011
Detection, characterization and quantitation of coxsackievirus A16 using polyclonal antibodies against recombinant capsid subunit proteins, Liu Q, Ku Z, Cai Y, Sun B, Leng Q, Huang Z., 2011
Single-Particle Tracking of Hepatitis B Virus-like Vesicle Entry into Cells, Hao X, Shang X, Wu J, Shan Y, Cai M, Jiang J, Huang Z, Tang Z, Wang H., 2011
Expression of VP0 protein of enterovirus 71 in E.coli and generation of corresponding polyclonal antibodies, Feng Y, Liu Q, Ku Z, Wen J, Shan H, Huang Z., 2011

Vaccine Antiviral Hand Foot And Mouth Disease Hepatitis C Norovirus Genetic Engineering Monoclonal Antibodies Virus-Like Particles Immunology Therapeutics

Hongbing Shu - Wuhan University

Jin Zhong - University of Chinese Academy of Sciences

Tao Deng - University of Chinese Academy of Sciences

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