1999-09--2004-08 Ph.D. in Science: Shanghai Institute of Life Sciences, Chinese Academy of Sciences
1994-09--1999-07 Bachelor's in Science: University of Science and Technology of China
2016-03~Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher
2012-09~2016-03 - Memorial Sloan Kettering Cancer Center - Senior Research Scientist
2009-09~2012-09 - Memorial Sloan Kettering Cancer Center - Research Associate
2008-07~2009-08 - Memorial Sloan Kettering Cancer Center - Research Scholar
2004-10~2008-07 - Memorial Sloan Kettering Cancer Center - Research Fellow
Shanghai Pudong New Area Pearl Engineer (2023): City Level
Shanghai Science and Technology System March 8th Red Banner Holder (2021): Provincial Level
Chinese Academy of Sciences Lico Researcher Fund (2018): Ministerial Level
Travel award from World Molecular Imaging Congress (2014): Other
Travel award from World Molecular Imaging Congress (2012): Other
Poster award from World Molecular Imaging Congress (2012): Other
Travel award from World Molecular Imaging Congress (2008): Other
Travel award from the Fifth Annual Meeting of the Society for Molecular Imaging (2006): Other
Travel award from the magic bullet a century later: the third La Jolla conference (2005): Other
Chinese Academy of Sciences President's Award for Excellence (2004): First Prize, Institute Level
Guo Moruo Scholarship, University of Science and Technology of China (1998): First Prize, School Level
Research
Molecular Imaging of Drugs Tumor Pharmacology
Label-free Raman spectroscopy for the assessment of liver fibrosis, MedComm Future Medicine, 2023
Method for the refractive index of various tissues based on fluorescence microscopy, Optics Continuum, 2023
Cancer-associated fibroblast-derived miR-146a-5p generates a niche that promotes bladder cancer stemness and chemoresistance, Cancer Research, 2023
Perfluoro-tert-butyl group-derived capmatinib: synthesis, biological evaluation and its application in 19F magnetic resonance imaging, ChemBiochem, 2023
Integrative analysis of the ST6GALNAC family identifies GATA2-upregulated ST6GALNAC5 as an adverse prognostic biomarker promoting prostate cancer cell invasion, Cancer Cell International, 2023
A c-MET-Targeted Topical Fluorescent Probe cMBP-ICG Improves Oral Squamous Cell Carcinoma Detection in Humans, ANNALS OF SURGICAL ONCOLOGY, 2023
Modulation of MRSA virulence gene expression by the wall teichoic acid enzyme TarO, NATURE COMMUNICATIONS, 2023
18 F-FDG PET as an imaging biomarker for the response to FGFR-targeted therapy of cancer cells via FGFR-initiated mTOR, THERANOSTICS, 2022
Identification of ST3GAL5 as a prognostic biomarker correlating with CD8(+) T cell exhaustion in clear cell renal cell carcinoma, FRONTIERS IN IMMUNOLOGY, 2022
Rauwolfia vomitoria extract suppresses benign prostatic hyperplasia by inducing autophagic apoptosis through endoplasmic reticulum stress, BMCCOMPLEMENTARYMEDICINEANDTHERAPIES, 2022
Information Entropy-Based Strategy for the Quantitative Evaluation of Extensive Hyperspectral Images to Better Unveil Spatial Heterogeneity in Mass Spectrometry Imaging, ANALYTICAL CHEMISTRY, 2022
Comprehensive landscape of the ST3GAL family reveals the significance of ST3GAL6-AS1/ST3GAL6 axis on EGFR signaling in lung adenocarcinoma cell invasion, FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022
Identification of hexosamine biosynthesis pathway as a novel prognostic signature and its correlation with immune infiltration in bladder cancer, FRONTIERS IN MOLECULAR BIOSCIENCES, 2022
Nuclear miR-30b-5p suppresses TFEB-mediated lysosomal biogenesis and autophagy, CELL DEATH AND DIFFERENTIATION, 2021
Oxidized Low-Density Lipoprotein Links Hypercholesterolemia and Bladder Cancer Aggressiveness by Promoting Cancer Stemness, CANCER RESEARCH, 2021
Genetically Encoded Benzoyllysines Serve as Versatile Probes for Interrogating Histone Benzoylation and Interactions in Living Cells, ACS CHEMICAL BIOLOGY, 2021
CBX7 suppresses urinary bladder cancer progression via modulating AKR1B10-ERK signaling, CELL DEATH & DISEASE, 2021
Reprogramming the immunosuppressive microenvironment of IDH1 wild-type glioblastoma by blocking Wnt signaling between microglia and cancer cells, ONCOIMMUNOLOGY, 2021
PDE4B Induces Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Is Transcriptionally Suppressed by CBX7, FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021
Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer, JOURNAL OF MEDICINAL CHEMISTRY, 2021
Define Mesenchymal Stem Cell from Its Fate: Biodisposition of Human Mesenchymal Stem Cells in Normal and Concanavalin A-Induced Liver Injury Mice, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2021
Single cell Raman spectroscopy to identify different stages of proliferating human hepatocytes for cell therapy, STEM CELL RESEARCH & THERAPY, 2021
Identification of glycogene-type and validation of ST3GAL6 as a biomarker predicts clinical outcome and cancer cell invasion in urinary bladder cancer, THERANOSTICS, 2020
Identification of Highly Selective Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitors by a Covalent Fragment-Based Approach, JOURNAL OF MEDICINAL CHEMISTRY, 2020
Pao Pereira extract suppresses benign prostatic hyperplasia by inhibiting inflammation-associated NF kappa B signaling, BMC COMPLEMENTARY MEDICINE AND THERAPIES, 2020
Light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation, NATURE COMMUNICATIONS, 2020
Downregulation of TET1 Promotes Bladder Cancer Cell Proliferation and Invasion by Reducing DNA Hydroxymethylation of AJAP1, FRONTIERS IN ONCOLOGY, 2020
A pH ratiometrically responsive surface enhanced resonance Raman scattering probe for tumor acidic margin delineation and image-guided surgery, CHEMICAL SCIENCE, 2020
MiR-629-5p promotes the invasion of lung adenocarcinoma via increasing both tumor cell invasion and endothelial cell permeability, ONCOGENE, 2020
Solution-processed upconversion photodetectors based on quantum dots, NATURE ELECTRONICS, 2020
Three dimensional drift control at nano-scale in single molecule localization microscopy, OPTICS EXPRESS, 2020
Selective N-glycan editing on living cell surfaces to probe glycoconjugate function, NATURE CHEMICAL BIOLOGY, 2020
Detection of Premalignant Gastrointestinal Lesions Using Surface-Enhanced Resonance Raman Scattering Nanoparticle Endoscopy, ACS NANO, 2019
Inhibition of G9a by a small molecule inhibitor, UNC0642, induces apoptosis of human bladder cancer cells., ACTA PHARMACOLOGICA SINICA, 2019
Imaging Tumorous Methylglyoxal by an Activatable Near-Infrared Fluorescent Probe for Monitoring Glyoxalase 1 Activity, ANALYTICAL CHEMISTRY, 2019
Inhibition of G9a by a small molecule inhibitor, UNC0642, induces apoptosis of human bladder cancer cells, 中国药理学报:英文版, 2019
Metabolic Evaluation of MYCN-Amplified Neuroblastoma by 4-18FFGln
Area of Focus
Nir-Ii Probes | Organic Molecules | Small Molecules | Tumor Visualization | Viral Mechanisms | Drug Development | Molecular Imaging | Biomedical Imaging | Cancer Research | Therapeutic Agents
Area of Focus
Molecular Imaging | Malignant Tumors | Theranostics | Pet | Probe Development | Clinical Transformation | Precision Medicine | Oncology | Biomedical Imaging | Research
