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Hao Chen
Medical School
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English
Contact
Drug Chemistry Pharmacology Molecular Imaging Pet Imaging Fluorescent Probes Cancer Therapy Near-Infrared Imaging Photothermal Therapy Biomedical Imaging Mitochondria-Targeted Dyes
Areas of Focus
  • Drug Chemistry
  • Pharmacology
  • Molecular Imaging
Work Experience
  • 2019-02~Present - Chinese Academy of Sciences Shanghai Institute of Materia Medica - Researcher
  • 2015-06~2019-02 - Stanford University - Postdoctoral Researcher
  • 2014-02~2015-07 - Stanford University - Joint PhD
  • 2009-09~2015-06 - Wuhan University - PhD Student
  • 2005-09~2009-06 - Wuhan University - Bachelor's Degree
Academic Background & Achievements
  • 2014-02--2015-07 Joint PhD: Stanford University
  • 2009-09--2015-06 PhD: Wuhan University
  • 2005-09--2009-06 Bachelor's Degree: Wuhan University
Publications
  • Development of a Novel 18F-Labeled Probe for PET Imaging of Estrogen Receptor beta, JOURNAL OF MEDICINAL CHEMISTRY, 2023
  • Hypsochromic Shift Donor—Acceptor NIR-II Dye for High-Efficiency Tumor Imaging, JOURNAL OF MEDICINAL CHEMISTRY, 2023
  • Development of a Novel F-18-Labeled Probe for PET Imaging of Estrogen Receptor beta, JOURNAL OF MEDICINAL CHEMISTRY, 2023
  • Liver injury long-term monitoring and fluorescent image-guided tumor surgery using self-assembly amphiphilic donor-acceptor NIR-II dyes, BIOSENSORS & BIOELECTRONICS, 2022
  • A Small-Molecule Based Organic Nanoparticle for Photothermal Therapy and Near-Infrared-IIb Imaging, ACS APPLIED MATERIALS & INTERFACES, 2022
  • Development of Mitochondria-Targeted Small-Molecule Dyes for Myocardial PET and Fluorescence Bimodal Imaging, JOURNAL OF MEDICINAL CHEMISTRY, 2022
  • Stable, Bright, and Long-Fluorescence-Lifetime Dyes for Deep-Near- Infrared Bioimaging, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2022
  • Bioinspired large Stokes shift small molecular dyes for biomedical fluorescence imaging, SCIENCE ADVANCES, 2022
  • Azide-Dye Unexpected Bone Targeting for Near-Infrared Window II Osteoporosis Imaging, JOURNAL OF MEDICINAL CHEMISTRY, 2021
  • Engineering Oxaliplatin Prodrug Nanoparticles for Second Near-Infrared Fluorescence Imaging-Guided Immunotherapy of Colorectal Cancer, SMALL, 2021
  • Development of Mitochondria-Targeted Small-Molecule Dyes for Myocardial PET and Fluorescence Bimodal Imaging, JOURNAL OF MEDICINAL CHEMISTRY, 2021
  • Smart Self-Assembly Amphiphilic Cyclopeptide-Dye for Near-Infrared Window-II Imaging, ADVANCED MATERIALS, 2021
  • Semiconducting Polymer Nanoparticles as Theranostic System for Near-Infrared-II Fluorescence Imaging and Photothermal Therapy under Safe Laser Fluence, ACS NANO, 2020
  • Mitochondria-targeting fluorescent molecules for high efficiency cancer growth inhibition and imaging, CHEMICAL SCIENCE, 2019
  • Diketopyrrolopyrrole-based semiconducting polymer nanoparticles for in vivo second near-infrared window imaging and image-guided tumor surgery, CHEMICAL SCIENCE, 2018
  • A high quantum yield molecule-protein complex fluorophore for near-infrared II imaging, NATURE COMMUNICATIONS, 2017
  • Synthesis, Characterization, and Biomedical Applications of a Targeted Dual-Modal Near-Infrared-II Fluorescence and Photoacoustic Imaging Nanoprobe, ACS NANO, 2017
  • Live imaging of follicle stimulating hormone receptors in gonads and bones using near infrared II fluorophore, CHEMICAL SCIENCE, 2017
  • Strained Cyclooctyne as a Molecular Platform for Construction of Multimodal Imaging Probes, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015
  • HMDO-Promoted Peptide and Protein Synthesis in Ionic Liquids, JOURNAL OF ORGANIC CHEMISTRY, 2013
  • A simple and straightforward approach toward selective C = C bond reduction by hydrazine, CANADIAN JOURNAL OF CHEMISTRY, 2012
  • Metal-free direct amidation of peptidyl thiol esters with alpha-amino acid esters, GREEN CHEMISTRY, 2011
Awards
  • Lingang Laboratory 'Qiusuo Outstanding Youth Program' (2022): Provincial Level
  • Shanghai Pujiang Talent (2019): Provincial Level
  • CMIIT Young Researcher Award (2017): Third Prize, Other
  • Young Scientist Award (2017): Second Prize, Other
  • CMIIT Young Researcher Award (2016): Third Prize, Other
  • Young Scientist Award (2016): First Prize, Other
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