Professor | 陈浩 | 数字化转型顾问

Name	陈浩
Contact Information	haoc@simm.ac.cn
Language ability	中文, 英语
Province	上海

Name

陈浩

Contact Information

haoc@simm.ac.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	中国科学院大学
Faculty	Medical School
Academic Background & Achievements	2014-02--2015-07 联合培养博士: 斯坦福大学 2009-09--2015-06 博士研究生: 武汉大学 2005-09--2009-06 本科学历学士学位: 武汉大学
Work Experience	2019-02~现在 - 中国科学院上海药物研究所 - 研究员 2015-06~2019-02 - 斯坦福大学 - 博士后 2014-02~2015-07 - 斯坦福大学 - 联合培养博士 2009-09~2015-06 - 武汉大学 - 博士研究生 2005-09~2009-06 - 武汉大学 - 本科学历学士学位
Awards	临港实验室“求索杰出青年计划” (2022): 省级上海市浦江人才 (2019): 省级分子影像创新与转化中心(CMIIT)青年研究学者奖 (2017): 三等奖, 其他青年科学家奖 (2017): 二等奖, 其他分子影像创新与转化中心(CMIIT)青年研究学者奖 (2016): 三等奖, 其他青年科学家奖 (2016): 一等奖, 其他

University/Lab Affiliation and Title

中国科学院大学

Faculty

Medical School

Academic Background & Achievements

2014-02--2015-07 联合培养博士: 斯坦福大学
2009-09--2015-06 博士研究生: 武汉大学
2005-09--2009-06 本科学历学士学位: 武汉大学

Work Experience

2019-02~现在 - 中国科学院上海药物研究所 - 研究员
2015-06~2019-02 - 斯坦福大学 - 博士后
2014-02~2015-07 - 斯坦福大学 - 联合培养博士
2009-09~2015-06 - 武汉大学 - 博士研究生
2005-09~2009-06 - 武汉大学 - 本科学历学士学位

Awards

临港实验室“求索杰出青年计划” (2022): 省级
上海市浦江人才 (2019): 省级
分子影像创新与转化中心(CMIIT)青年研究学者奖 (2017): 三等奖, 其他
青年科学家奖 (2017): 二等奖, 其他
分子影像创新与转化中心(CMIIT)青年研究学者奖 (2016): 三等奖, 其他
青年科学家奖 (2016): 一等奖, 其他

Areas of Focus	药物化学药理学分子影像
Publications	Development of a Novel 18F-Labeled Probe for PET Imaging of Estrogen Receptor beta, JOURNAL OF MEDICINAL CHEMISTRY, 2023 Hypsochromic Shift Donor—Acceptor NIR-II Dye for High-Efficiency Tumor Imaging, JOURNAL OF MEDICINAL CHEMISTRY, 2023 Development of a Novel F-18-Labeled Probe for PET Imaging of Estrogen Receptor beta, JOURNAL OF MEDICINAL CHEMISTRY, 2023 Liver injury long-term monitoring and fluorescent image-guided tumor surgery using self-assembly amphiphilic donor-acceptor NIR-II dyes, BIOSENSORS & BIOELECTRONICS, 2022 A Small-Molecule Based Organic Nanoparticle for Photothermal Therapy and Near-Infrared-IIb Imaging, ACS APPLIED MATERIALS & INTERFACES, 2022 Development of Mitochondria-Targeted Small-Molecule Dyes for Myocardial PET and Fluorescence Bimodal Imaging, JOURNAL OF MEDICINAL CHEMISTRY, 2022 Stable, Bright, and Long-Fluorescence-Lifetime Dyes for Deep-Near- Infrared Bioimaging, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2022 Bioinspired large Stokes shift small molecular dyes for biomedical fluorescence imaging, SCIENCE ADVANCES, 2022 Azide-Dye Unexpected Bone Targeting for Near-Infrared Window II Osteoporosis Imaging, JOURNAL OF MEDICINAL CHEMISTRY, 2021 Engineering Oxaliplatin Prodrug Nanoparticles for Second Near-Infrared Fluorescence Imaging-Guided Immunotherapy of Colorectal Cancer, SMALL, 2021 Development of Mitochondria-Targeted Small-Molecule Dyes for Myocardial PET and Fluorescence Bimodal Imaging, JOURNAL OF MEDICINAL CHEMISTRY, 2021 Smart Self-Assembly Amphiphilic Cyclopeptide-Dye for Near-Infrared Window-II Imaging, ADVANCED MATERIALS, 2021 Semiconducting Polymer Nanoparticles as Theranostic System for Near-Infrared-II Fluorescence Imaging and Photothermal Therapy under Safe Laser Fluence, ACS NANO, 2020 Mitochondria-targeting fluorescent molecules for high efficiency cancer growth inhibition and imaging, CHEMICAL SCIENCE, 2019 Diketopyrrolopyrrole-based semiconducting polymer nanoparticles for in vivo second near-infrared window imaging and image-guided tumor surgery, CHEMICAL SCIENCE, 2018 A high quantum yield molecule-protein complex fluorophore for near-infrared II imaging, NATURE COMMUNICATIONS, 2017 Synthesis, Characterization, and Biomedical Applications of a Targeted Dual-Modal Near-Infrared-II Fluorescence and Photoacoustic Imaging Nanoprobe, ACS NANO, 2017 Live imaging of follicle stimulating hormone receptors in gonads and bones using near infrared II fluorophore, CHEMICAL SCIENCE, 2017 Strained Cyclooctyne as a Molecular Platform for Construction of Multimodal Imaging Probes, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015 HMDO-Promoted Peptide and Protein Synthesis in Ionic Liquids, JOURNAL OF ORGANIC CHEMISTRY, 2013 A simple and straightforward approach toward selective C = C bond reduction by hydrazine, CANADIAN JOURNAL OF CHEMISTRY, 2012 Metal-free direct amidation of peptidyl thiol esters with alpha-amino acid esters, GREEN CHEMISTRY, 2011

Areas of Focus

药物化学
药理学
分子影像

Publications

Development of a Novel 18F-Labeled Probe for PET Imaging of Estrogen Receptor beta, JOURNAL OF MEDICINAL CHEMISTRY, 2023
Hypsochromic Shift Donor—Acceptor NIR-II Dye for High-Efficiency Tumor Imaging, JOURNAL OF MEDICINAL CHEMISTRY, 2023
Development of a Novel F-18-Labeled Probe for PET Imaging of Estrogen Receptor beta, JOURNAL OF MEDICINAL CHEMISTRY, 2023
Liver injury long-term monitoring and fluorescent image-guided tumor surgery using self-assembly amphiphilic donor-acceptor NIR-II dyes, BIOSENSORS & BIOELECTRONICS, 2022
A Small-Molecule Based Organic Nanoparticle for Photothermal Therapy and Near-Infrared-IIb Imaging, ACS APPLIED MATERIALS & INTERFACES, 2022
Development of Mitochondria-Targeted Small-Molecule Dyes for Myocardial PET and Fluorescence Bimodal Imaging, JOURNAL OF MEDICINAL CHEMISTRY, 2022
Stable, Bright, and Long-Fluorescence-Lifetime Dyes for Deep-Near- Infrared Bioimaging, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2022
Bioinspired large Stokes shift small molecular dyes for biomedical fluorescence imaging, SCIENCE ADVANCES, 2022
Azide-Dye Unexpected Bone Targeting for Near-Infrared Window II Osteoporosis Imaging, JOURNAL OF MEDICINAL CHEMISTRY, 2021
Engineering Oxaliplatin Prodrug Nanoparticles for Second Near-Infrared Fluorescence Imaging-Guided Immunotherapy of Colorectal Cancer, SMALL, 2021
Development of Mitochondria-Targeted Small-Molecule Dyes for Myocardial PET and Fluorescence Bimodal Imaging, JOURNAL OF MEDICINAL CHEMISTRY, 2021
Smart Self-Assembly Amphiphilic Cyclopeptide-Dye for Near-Infrared Window-II Imaging, ADVANCED MATERIALS, 2021
Semiconducting Polymer Nanoparticles as Theranostic System for Near-Infrared-II Fluorescence Imaging and Photothermal Therapy under Safe Laser Fluence, ACS NANO, 2020
Mitochondria-targeting fluorescent molecules for high efficiency cancer growth inhibition and imaging, CHEMICAL SCIENCE, 2019
Diketopyrrolopyrrole-based semiconducting polymer nanoparticles for in vivo second near-infrared window imaging and image-guided tumor surgery, CHEMICAL SCIENCE, 2018
A high quantum yield molecule-protein complex fluorophore for near-infrared II imaging, NATURE COMMUNICATIONS, 2017
Synthesis, Characterization, and Biomedical Applications of a Targeted Dual-Modal Near-Infrared-II Fluorescence and Photoacoustic Imaging Nanoprobe, ACS NANO, 2017
Live imaging of follicle stimulating hormone receptors in gonads and bones using near infrared II fluorophore, CHEMICAL SCIENCE, 2017
Strained Cyclooctyne as a Molecular Platform for Construction of Multimodal Imaging Probes, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015
HMDO-Promoted Peptide and Protein Synthesis in Ionic Liquids, JOURNAL OF ORGANIC CHEMISTRY, 2013
A simple and straightforward approach toward selective C = C bond reduction by hydrazine, CANADIAN JOURNAL OF CHEMISTRY, 2012
Metal-free direct amidation of peptidyl thiol esters with alpha-amino acid esters, GREEN CHEMISTRY, 2011

药物化学药理学分子影像 Pet成像荧光探针癌症治疗近红外成像光热治疗生物医学成像线粒体靶向染料

程震 - 中国科学院大学

洪浩 - 南京大学

黄锐敏 - 中国科学院大学

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