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Jing Liu
Medical School
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English
Contact
Cell Fate Systems Biology Stem Cells Chemical Biology Epigenetics Disease Models Organ Reconstruction Mathematical Modeling Biological Processes Regulation
Areas of Focus
  • Cell Fate Regulation and Systems Biology
  • Stem Cells and Chemical Biology
  • Epigenetics
  • Disease Models and Organ Reconstruction
  • Mathematical Modeling of Biological Processes
Work Experience
  • 2018-01~Present - Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences - Researcher
  • 2013-01~2017-12 - Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences - Associate Researcher
  • 2012-07~2012-12 - Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences - Assistant Researcher
Academic Background & Achievements
  • 2009-09--2012-06 Ph.D. in Science: Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
  • 2007-09--2009-08 M.Sc. in Science: Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
  • 2003-09--2007-06 B.Sc. in Science: Hubei University
Publications
  • Epigenetic reshaping through damage: promoting cell fate transition by BrdU and IdU incorporation, Jing Liu, 2024
  • H3K27ac mediated SS18/BAFs relocation regulates JUN induced pluripotent-somatic transition, Jing Liu, 2022
  • Static Magnetic Fields Regulate T-Type Calcium Ion Channels and Mediate Mesenchymal Stem Cells Proliferation, Jing Liu, 2022
  • BMP4 drives primed to naïve transition through PGC-like state, Jing Liu, 2022
  • CRISPR/Cas9-Mediated Suds3 Knockout Inhibited Mouse Embryonic Stem Cell Proliferation and Mesoderm/Endoderm Differentiation, Jing Liu, 2021
  • Forkhead box family transcription factors as versatile regulators for cellular reprogramming to pluripotency, Jing Liu, 2021
  • ScGSLC: An unsupervised graph similarity learning framework for single-cell RNA-seq data clustering, Jing Liu, 2021
  • AP-1 activity is a major barrier of human somatic cell reprogramming, Jing Liu, 2021
  • The nuclear factor CECR2 promotes somatic cell reprogramming by reorganizing the chromatin structure, Jing Liu, 2021
  • SS18 regulates pluripotent-somatic transition through phase separation, Jing Liu, 2021
  • BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling, Jing Liu, 2020
  • A Virus-Infected, Reprogrammed Somatic Cell-Derived Tumor Cell (VIReST) Vaccination Regime Can Prevent Initiation and Progression of Pancreatic Cancer, Jing Liu, 2020
  • Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Jdp2-Jhdm1b-Mkk6-Glis1-Nanog-Essrb-Sall4, Jing Liu, 2019
  • Resolving Cell Fate Decisions during Somatic Cell Reprogramming by Single-Cell RNA-Seq, Jing Liu, 2019
  • Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency, Jing Liu, 2019
  • Mettl17, a regulator of mitochondrial ribosomal RNA modifications, is required for the translation of mitochondrial coding genes, Jing Liu, 2019
  • Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency, Jing Liu, 2018
  • Chromatin Accessibility Dynamics during iPSC Reprogramming, Jing Liu, 2017
  • Chemical reprogramming of mouse embryonic and adult fibroblast into endoderm lineage, Jing Liu, 2017
  • Kdm2b Regulates Somatic Reprogramming through Variant PRC1 Complex-Dependent Function, Jing Liu, 2017
  • Perspective of stem cell and regenerative medicine, Jing Liu, 2016
  • Cyclin-dependent Kinase-mediated Sox2 Phosphorylation Enhances the Ability of Sox2 to Establish the Pluripotent State, Jing Liu, 2015
  • The oncogene c-Jun impedes somatic cell reprogramming, Jing Liu, 2015
  • Sequential introduction of reprogramming factors reveals a time-sensitive requirement for individual factors and a sequential EMT-MET mechanism for optimal reprogramming, Jing Liu, 2013
  • H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs, Jing Liu, 2013
  • Optimization and Mechanism Study of Induced Reprogramming Culture System, Jing Liu, 2012
  • BMPs functionally replace KLf4, and support efficient reprogramming of mouse fibroblasts by Oct4 alone, Jing Liu, 2011
  • Rational optimization of reprogramming culture conditions for the generation of induced pluripotent stem cells with ultra-high efficiency and fast kinetics, Jing Liu, 2011
  • Reprogramming of mouse and human somatic cells by high-performance engineered factors, Jing Liu, 2011
  • Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells, Jing Liu, 2011
  • Towards an Optimized Culture Medium for the Generation of Mouse Induced Pluripotent Stem Cells, Jing Liu, 2010
Awards
  • Outstanding Scientific Achievement Award, Chinese Academy of Sciences (2017)
  • First Prize in MET Research in iPS Cell Induction (2014)
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