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Hezhe Lu
Medical School
University of Chinese Academy of Sciences
Beijing
Language: Chinese, English
Contact
Cell Heterogeneity Cell Fate Stem Cells Cancer Cell Division Genomics Proteomics Cell Signaling Tumor Biology Molecular Mechanisms
Areas of Focus
  • Cell Heterogeneity
  • Cell Fate Determination
Work Experience
  • 2020-07 to Present - Institute of Zoology, Chinese Academy of Sciences - Group Leader of Cell Heterogeneity and Fate Determination Research Group
  • 2016-10 to 2020-06 - Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital - Postdoctoral Fellow
  • 2011-09 to 2016-06 - University of Pennsylvania - Postdoctoral Fellow
  • 2006-09 to 2011-06 - Beijing Normal University - PhD
Academic Background & Achievements
  • 2006-09 to 2011-06 PhD: Beijing Normal University
Publications
  • Identification of IRAK1BP1 as a candidate prognostic factor in lung adenocarcinoma, Hezhe Lu, 2023
  • Wip1 inhibits neutrophil extracellular traps to promote abscess formation in mice by directly dephosphorylating Coronin-1a, Hezhe Lu, 2023
  • Distinct genomic features between osteosarcomas firstly metastasing to bone and to lung, Hezhe Lu, 2023
  • Asymmetric Cell Division and Tumor Heterogeneity, Hezhe Lu, 2022
  • TGF-β Signaling and Resistance to Cancer Therapy, Hezhe Lu, 2021
  • PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas, Hezhe Lu, 2017
  • Oncogenica BRAF-induced invadopodia formation and melanoma invasion, Hezhe Lu, 2016
  • Exo70 isoform switching upon Epithelial-Mesenchymal transition mediates cancer cell invasion, Hezhe Lu, 2013
  • Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation, Hezhe Lu, 2012
  • MicroRNA-9 up-regulates E-cadherin through inhibition of NF-κB1-snail1 pathway in melanoma, Hezhe Lu, 2012
  • An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition, Hezhe Lu, 2010
  • Cyr61 Is Up-Regulated in Prostate Cancer and Associated With the p53 Gene Status, Hezhe Lu, 2009
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