Professor | Hezhe Lu | Asia Growth Partners

Name

Hezhe Lu

Contact Information

hezhe@ioz.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2006-09 to 2011-06 PhD: Beijing Normal University
Work Experience	2020-07 to Present - Institute of Zoology, Chinese Academy of Sciences - Group Leader of Cell Heterogeneity and Fate Determination Research Group 2016-10 to 2020-06 - Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital - Postdoctoral Fellow 2011-09 to 2016-06 - University of Pennsylvania - Postdoctoral Fellow 2006-09 to 2011-06 - Beijing Normal University - PhD

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

Work Experience

2020-07 to Present - Institute of Zoology, Chinese Academy of Sciences - Group Leader of Cell Heterogeneity and Fate Determination Research Group
2016-10 to 2020-06 - Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital - Postdoctoral Fellow
2011-09 to 2016-06 - University of Pennsylvania - Postdoctoral Fellow
2006-09 to 2011-06 - Beijing Normal University - PhD

Areas of Focus	Cell Heterogeneity Cell Fate Determination
Publications	Identification of IRAK1BP1 as a candidate prognostic factor in lung adenocarcinoma, Hezhe Lu, 2023 Wip1 inhibits neutrophil extracellular traps to promote abscess formation in mice by directly dephosphorylating Coronin-1a, Hezhe Lu, 2023 Distinct genomic features between osteosarcomas firstly metastasing to bone and to lung, Hezhe Lu, 2023 Asymmetric Cell Division and Tumor Heterogeneity, Hezhe Lu, 2022 TGF-β Signaling and Resistance to Cancer Therapy, Hezhe Lu, 2021 PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas, Hezhe Lu, 2017 Oncogenica BRAF-induced invadopodia formation and melanoma invasion, Hezhe Lu, 2016 Exo70 isoform switching upon Epithelial-Mesenchymal transition mediates cancer cell invasion, Hezhe Lu, 2013 Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation, Hezhe Lu, 2012 MicroRNA-9 up-regulates E-cadherin through inhibition of NF-κB1-snail1 pathway in melanoma, Hezhe Lu, 2012 An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition, Hezhe Lu, 2010 Cyr61 Is Up-Regulated in Prostate Cancer and Associated With the p53 Gene Status, Hezhe Lu, 2009

Areas of Focus

Cell Heterogeneity
Cell Fate Determination

Publications

Identification of IRAK1BP1 as a candidate prognostic factor in lung adenocarcinoma, Hezhe Lu, 2023
Wip1 inhibits neutrophil extracellular traps to promote abscess formation in mice by directly dephosphorylating Coronin-1a, Hezhe Lu, 2023
Distinct genomic features between osteosarcomas firstly metastasing to bone and to lung, Hezhe Lu, 2023
Asymmetric Cell Division and Tumor Heterogeneity, Hezhe Lu, 2022
TGF-β Signaling and Resistance to Cancer Therapy, Hezhe Lu, 2021
PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas, Hezhe Lu, 2017
Oncogenica BRAF-induced invadopodia formation and melanoma invasion, Hezhe Lu, 2016
Exo70 isoform switching upon Epithelial-Mesenchymal transition mediates cancer cell invasion, Hezhe Lu, 2013
Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation, Hezhe Lu, 2012
MicroRNA-9 up-regulates E-cadherin through inhibition of NF-κB1-snail1 pathway in melanoma, Hezhe Lu, 2012
An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition, Hezhe Lu, 2010
Cyr61 Is Up-Regulated in Prostate Cancer and Associated With the p53 Gene Status, Hezhe Lu, 2009

Cell Heterogeneity Cell Fate Stem Cells Cancer Cell Division Genomics Proteomics Cell Signaling Tumor Biology Molecular Mechanisms

Shenying Fang - Southern University of Science and Technology

Xinran Li - Wuhan University

Han Han - Wuhan University

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