Professor | 吕赫喆 | 数字化转型顾问

Name

吕赫喆

Contact Information

hezhe@ioz.ac.cn

Language ability

中文, 英语

Province

北京

University/Lab Affiliation and Title	中国科学院大学
Faculty	Medical School
Academic Background & Achievements	2006-09 至 2011-06 博士: 北京师范大学
Work Experience	2020-07 至今 - 中科院动物研究所 - 细胞异质性与命运决定研究组组长 2016-10 至 2020-06 - 西奈山医院Lunenfeld-Tanenbaum研究所 - 博士后 2011-09 至 2016-06 - 宾夕法尼亚大学 - 博士后 2006-09 至 2011-06 - 北京师范大学 - 博士

University/Lab Affiliation and Title

中国科学院大学

Faculty

Medical School

Academic Background & Achievements

Work Experience

Areas of Focus	细胞异质性细胞命运决定
Publications	Identification of IRAK1BP1 as a candidate prognostic factor in lung adenocarcinoma, 吕赫喆, 2023 Wip1 inhibits neutrophil extracellular traps to promote abscess formation in mice by directly dephosphorylating Coronin-1a, 吕赫喆, 2023 Distinct genomic features between osteosarcomas firstly metastasing to bone and to lung, 吕赫喆, 2023 Asymmetric Cell Division and Tumor Heterogeneity, 吕赫喆, 2022 TGF-β Signaling and Resistance to Cancer Therapy, 吕赫喆, 2021 PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas, 吕赫喆, 2017 Oncogenica BRAF-induced invadopodia formation and melanoma invasion, 吕赫喆, 2016 Exo70 isoform switching upon Epithelial-Mesenchymal transition mediates cancer cell invasion, 吕赫喆, 2013 Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation, 吕赫喆, 2012 MicroRNA-9 up-regulates E-cadherin through inhibition of NF-κB1-snail1 pathway in melanoma, 吕赫喆, 2012 An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition, 吕赫喆, 2010 Cyr61 Is Up-Regulated in Prostate Cancer and Associated With the p53 Gene Status, 吕赫喆, 2009

Areas of Focus

细胞异质性
细胞命运决定

Publications

Identification of IRAK1BP1 as a candidate prognostic factor in lung adenocarcinoma, 吕赫喆, 2023
Wip1 inhibits neutrophil extracellular traps to promote abscess formation in mice by directly dephosphorylating Coronin-1a, 吕赫喆, 2023
Distinct genomic features between osteosarcomas firstly metastasing to bone and to lung, 吕赫喆, 2023
Asymmetric Cell Division and Tumor Heterogeneity, 吕赫喆, 2022
TGF-β Signaling and Resistance to Cancer Therapy, 吕赫喆, 2021
PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas, 吕赫喆, 2017
Oncogenica BRAF-induced invadopodia formation and melanoma invasion, 吕赫喆, 2016
Exo70 isoform switching upon Epithelial-Mesenchymal transition mediates cancer cell invasion, 吕赫喆, 2013
Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation, 吕赫喆, 2012
MicroRNA-9 up-regulates E-cadherin through inhibition of NF-κB1-snail1 pathway in melanoma, 吕赫喆, 2012
An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition, 吕赫喆, 2010
Cyr61 Is Up-Regulated in Prostate Cancer and Associated With the p53 Gene Status, 吕赫喆, 2009

细胞异质性细胞命运干细胞癌症细胞分裂基因组学蛋白质组学细胞信号肿瘤生物学分子机制

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