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Wenqiang Liu
Life Science
Tongji University
Shanghai
Language: Chinese, English
Contact
Embryo Development Mammalian Biology Human Genetics Reproductive Technology Developmental Biology Genetic Disorders Infertility Assisted Reproduction Embryology Genetic Mechanisms
Areas of Focus
  • Mammalian and human early embryo development regulation
  • Mechanisms and interventions of abnormal embryo development
  • Genetic mechanisms of infertility and assisted reproductive technology
Work Experience
  • 2014-present - Tongji University / Tongji University Affiliated Obstetrics and Gynecology Hospital - Professor
Academic Background & Achievements
  • 2007 Bachelor's Degree: Northwest A&F University
  • 2010 Master's Degree: Northwest A&F University
  • 2014 PhD: China Agricultural University / Beijing Institute of Life Sciences
  • Awards: First Prize of Natural Science Award from the Ministry of Education, Youth May Fourth Medal of Tongji University
Publications
  • Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy, Wenqiang Liu et al., 2024
  • Inhibition of Wnt activity improves periimplantation development of somatic cell nuclear transfer embryos, Wenqiang Liu et al., 2023
  • Bilineage embryo-like structure from EPS cells can produce live mice with tetraploid trophectoderm, Wenqiang Liu et al., 2023
  • Allele-specific H3K9me3 and DNA methylation co-marked CpG-rich regions serve as potential imprinting control regions in pre-implantation embryo, Wenqiang Liu et al., 2022
  • Aberrant H3K4me3 modification of epiblast genes of extraembryonic tissue causes placental defects and implantation failure in mouse IVF embryos, Wenqiang Liu et al., 2022
  • Dux-Mediated Corrections of Aberrant H3K9ac during 2-Cell Genome Activation Optimize Efficiency of Somatic Cell Nuclear Transfer, Wenqiang Liu et al., 2021
  • Precise allele-specific genome editing by spatiotemporal control of CRISPR-Cas9 via pronuclear transplantation, Wenqiang Liu et al., 2020
  • A DNA methylation state transition model reveals the programmed epigenetic heterogeneity in human pre-implantation embryos, Wenqiang Liu et al., 2020
  • Genome transfer for the prevention of female infertility caused by maternal gene mutation, Wenqiang Liu et al., 2020
  • Distinct H3K9me3 and DNA methylation modifications during mouse spermatogenesis., Wenqiang Liu et al., 2019
  • Inhibition of Aberrant DNA Re-methylation Improves Post-implantation Development of Somatic Cell Nuclear Transfer Embryos, Wenqiang Liu et al., 2018
  • Dosage effects of ZP2 and ZP3 heterozygous mutations cause human infertility, Wenqiang Liu et al., 2017
  • Polarization microscopy imaging for the identification of unfertilized oocytes following short-term insemination, Wenqiang Liu et al., 2017
  • Distinct features of H3K4me3 and H3K27me3 chromatin domains in pre-implantation embryos, Wenqiang Liu et al., 2016
  • Identification of key factors conquering developmental arrest of somatic cell cloned embryos by combining embryo biopsy and single-cell sequencing, Wenqiang Liu et al., 2016
  • Asymmetric reprogramming capacity of parental pronuclei in mouse zygotes, Wenqiang Liu et al., 2014
Awards
  • National Natural Science Foundation Outstanding Youth Project, Shanghai Top Young Talents Program, Shanghai Science and Technology Rising-Star Program
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