Professor | Wenqiang Liu | Asia Growth Partners

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Name	Wenqiang Liu
Contact Information	liuwenqiang@tongji.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Wenqiang Liu

Contact Information

liuwenqiang@tongji.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	2007 - Bachelor's Degree: Northwest A&F University 2010 - Master's Degree: Northwest A&F University 2014 - PhD: China Agricultural University / Beijing Institute of Life Sciences Selected for National Natural Science Foundation Outstanding Youth Project, Shanghai Youth Top Talent Plan, Shanghai Science and Technology Star Plan Received First Prize of Natural Science Award from the Ministry of Education, Tongji University 'Youth May Fourth Medal'
Work Experience	2014-present - Tongji University / Tongji University Affiliated Obstetrics and Gynecology Hospital: Professor and Researcher
Awards	National Natural Science Foundation Outstanding Youth Project First Prize of Natural Science Award from the Ministry of Education Tongji University 'Youth May Fourth Medal'

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

2007 - Bachelor's Degree: Northwest A&F University
2010 - Master's Degree: Northwest A&F University
2014 - PhD: China Agricultural University / Beijing Institute of Life Sciences
Selected for National Natural Science Foundation Outstanding Youth Project, Shanghai Youth Top Talent Plan, Shanghai Science and Technology Star Plan
Received First Prize of Natural Science Award from the Ministry of Education, Tongji University 'Youth May Fourth Medal'

Work Experience

2014-present - Tongji University / Tongji University Affiliated Obstetrics and Gynecology Hospital: Professor and Researcher

Awards

National Natural Science Foundation Outstanding Youth Project
First Prize of Natural Science Award from the Ministry of Education
Tongji University 'Youth May Fourth Medal'

Areas of Focus	Mammalian and human early embryo development regulation Mechanisms and interventions of abnormal embryo development Genetic mechanisms of infertility and assisted reproductive technology
Publications	Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy, Wenqiang Liu et al., 2024 Inhibition of Wnt activity improves periimplantation development of somatic cell nuclear transfer embryos, Wenqiang Liu et al., 2023 Bilineage embryo-like structure from EPS cells can produce live mice with tetraploid trophectoderm, Wenqiang Liu et al., 2023 Allele-specific H3K9me3 and DNA methylation co-marked CpG-rich regions serve as potential imprinting control regions in pre-implantation embryo, Wenqiang Liu et al., 2022 Aberrant H3K4me3 modification of epiblast genes of extraembryonic tissue causes placental defects and implantation failure in mouse IVF embryos, Wenqiang Liu et al., 2022 Dux-Mediated Corrections of Aberrant H3K9ac during 2-Cell Genome Activation Optimize Efficiency of Somatic Cell Nuclear Transfer, Wenqiang Liu et al., 2021 Precise allele-specific genome editing by spatiotemporal control of CRISPR-Cas9 via pronuclear transplantation, Wenqiang Liu et al., 2020 A DNA methylation state transition model reveals the programmed epigenetic heterogeneity in human pre-implantation embryos, Wenqiang Liu et al., 2020 Genome transfer for the prevention of female infertility caused by maternal gene mutation, Wenqiang Liu et al., 2020 Distinct H3K9me3 and DNA methylation modifications during mouse spermatogenesis, Wenqiang Liu et al., 2019 Inhibition of Aberrant DNA Re-methylation Improves Post-implantation Development of Somatic Cell Nuclear Transfer Embryos, Wenqiang Liu et al., 2018 Dosage effects of ZP2 and ZP3 heterozygous mutations cause human infertility, Wenqiang Liu et al., 2017 Polarization microscopy imaging for the identification of unfertilized oocytes following short-term insemination, Wenqiang Liu et al., 2017 Distinct features of H3K4me3 and H3K27me3 chromatin domains in pre-implantation embryos, Wenqiang Liu et al., 2016 Identification of key factors conquering developmental arrest of somatic cell cloned embryos by combining embryo biopsy and single-cell sequencing, Wenqiang Liu et al., 2016 Asymmetric reprogramming capacity of parental pronuclei in mouse zygotes, Wenqiang Liu et al., 2014

Areas of Focus

Mammalian and human early embryo development regulation
Mechanisms and interventions of abnormal embryo development
Genetic mechanisms of infertility and assisted reproductive technology

Publications

Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy, Wenqiang Liu et al., 2024
Inhibition of Wnt activity improves periimplantation development of somatic cell nuclear transfer embryos, Wenqiang Liu et al., 2023
Bilineage embryo-like structure from EPS cells can produce live mice with tetraploid trophectoderm, Wenqiang Liu et al., 2023
Allele-specific H3K9me3 and DNA methylation co-marked CpG-rich regions serve as potential imprinting control regions in pre-implantation embryo, Wenqiang Liu et al., 2022
Aberrant H3K4me3 modification of epiblast genes of extraembryonic tissue causes placental defects and implantation failure in mouse IVF embryos, Wenqiang Liu et al., 2022
Dux-Mediated Corrections of Aberrant H3K9ac during 2-Cell Genome Activation Optimize Efficiency of Somatic Cell Nuclear Transfer, Wenqiang Liu et al., 2021
Precise allele-specific genome editing by spatiotemporal control of CRISPR-Cas9 via pronuclear transplantation, Wenqiang Liu et al., 2020
A DNA methylation state transition model reveals the programmed epigenetic heterogeneity in human pre-implantation embryos, Wenqiang Liu et al., 2020
Genome transfer for the prevention of female infertility caused by maternal gene mutation, Wenqiang Liu et al., 2020
Distinct H3K9me3 and DNA methylation modifications during mouse spermatogenesis, Wenqiang Liu et al., 2019
Inhibition of Aberrant DNA Re-methylation Improves Post-implantation Development of Somatic Cell Nuclear Transfer Embryos, Wenqiang Liu et al., 2018
Dosage effects of ZP2 and ZP3 heterozygous mutations cause human infertility, Wenqiang Liu et al., 2017
Polarization microscopy imaging for the identification of unfertilized oocytes following short-term insemination, Wenqiang Liu et al., 2017
Distinct features of H3K4me3 and H3K27me3 chromatin domains in pre-implantation embryos, Wenqiang Liu et al., 2016
Identification of key factors conquering developmental arrest of somatic cell cloned embryos by combining embryo biopsy and single-cell sequencing, Wenqiang Liu et al., 2016
Asymmetric reprogramming capacity of parental pronuclei in mouse zygotes, Wenqiang Liu et al., 2014

Embryo Development Mammalian Biology Human Genetics Reproductive Technology Developmental Biology Genetic Disorders Infertility Assisted Reproduction Embryology Genetic Mechanisms

Wenqiang Liu - Tongji University

Lu Qing - Shanghai Jiao Tong University

Xueyan Yang - Fudan University

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