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Yulin Li
Medical School
University of Chinese Academy of Sciences
Qinghai
Language: Chinese, English
Contact
Natural Products Pharmacology Drug Development Tibetan Medicine Standardization Chemistry Phytochemistry Bioactive Compounds Quality Control Herbal Medicine
Areas of Focus
  • Natural Product Chemistry and Pharmacology
  • Innovative Drug Development
  • Standardization of Tibetan Medicine
Work Experience
  • 2013-06~Present - Northwest Institute of Plateau Biology, Chinese Academy of Sciences - Researcher
  • 2004-06~2013-05 - Northwest Institute of Plateau Biology, Chinese Academy of Sciences - Associate Researcher
  • 1997-11~2004-06 - Northwest Institute of Plateau Biology, Chinese Academy of Sciences - Assistant Researcher
  • 1992-07~1997-11 - Northwest Institute of Plateau Biology, Chinese Academy of Sciences - Research Intern
Academic Background & Achievements
  • 2004-09--2007-07 Ph.D. in Science: Graduate School of the Chinese Academy of Sciences
  • 1988-09--1992-07 Bachelor's in Science: Sun Yat-sen University
Publications
  • Target-guided isolation and purification of cyclooxygenase-2 inhibitors from Meconopsis integrifolia (Maxim.) Franch. by high-speed counter-current chromatography combined with ultrafiltration liquid chromatography, Yulin Li, 2024
  • Rapid screening of potential β-glucosidase inhibitors from the waste leaves of Rheum tanguticum by activity-oriented extraction and enrichment optimization, UPLC-QTOF-MS/MS, molecular docking and in vitro validation, Yulin Li, 2024
  • Separation of a new triterpenoid saponin together with six known ones from Clematis tangutica (Maxim.) Korsh and evaluation of their cytotoxic activities, Yulin Li, 2023
  • UV-based solvent system screening for high-speed counter-current chromatography fractionation of compounds with similar UV absorption from complex samples followed by preparative HPLC purification: Flavonoids from barley seedlings as sample, Yulin Li, 2023
  • Nuclear magnetic resonance-based solvent system selection for counter-current chromatography separation of compounds present in the same high-performance liquid chromatography peak: Flavonoids in barley seedlings as an example, Yulin Li, 2023
  • Integrated strategy for the screening of cyclooxygenase-2 inhibitors from triterpenoid saponins in Clematis tangutica, Yulin Li, 2023
  • Separation of five flavone glycosides including two groups with similar polarities from Dracocephalum tanguticum by a combination of three high-speed counter-current chromatography modes, Yulin Li, 2022
  • Efficient One-Step Separation of Five Flavonoids from the Crude Extract of the Waste Pomace of Sea Buckthorn Berries through Counter-Current Chromatography, Yulin Li, 2022
  • Inhibitory effect of hederacoside B on HGC-27 gastric cancer cells and mechanism exploration based on bioinformatics, Yulin Li, 2022
  • Effect of anthocyanin extract from Lycium ruthenicum on acute gouty arthritis in rats, Yulin Li, 2022
  • Study on Pharmacognosy of Dracocephalum heterophyllum Benth., Yulin Li, 2022
  • Ab initio calculation based solvent system selection in silico for counter-current chromatography: Separation of resibufogenin glycosylation products, Yulin Li, 2022
  • Large-scale preparation of two minor polar polyphenols from Phyllanthus emblica Linn. by macroporous resin column chromatography and high-temperature preparative high-speed counter-current chromatography, Yulin Li, 2022
  • Large-scale preparation of five polar polyphenols including three isomers from Phyllanthus emblica Linn. by preparative high-speed counter-current chromatography, Yulin Li, 2022
  • Separation of eight phenolic compounds from the over-ground parts of Aconitum pendulum Busch by repeated injection high-speed counter-current chromatography, Yulin Li, 2022
  • The applicability of high-speed counter-current chromatography for preparative separation of biosynthesis products: Glycosylation products as example, Yulin Li, 2021
  • Rapid preparation and standardization analysis of gentianone from daisy leaves, Yulin Li, 2021
  • HSCCC Separation of Three Main Compounds from the Crude Extract of Dracocephalum Tanguticum by Using Dimethyl Sulfoxide as Cosolvent, Yulin Li, 2021
  • Separation and Standardization of Chebulinic Acid as Quality Marker of Tibetan Medicine Terminalia Chebula, Yulin Li, 2021
  • Current strategies for the development of fluorescence-based molecular probes for visualizing the enzymes and proteins associated with Alzheimer’s disease, Yulin Li, 2021
  • Uncertainty analysis of measurement of eight elements in feed by inductively coupled plasma emission spectrometry, Yulin Li, 2021
  • Effect of anthocyanidin of Lycium ruthenicum Murry from Qinghai Tibet Plateaun on the proliferation and autophagy of HepG2 cells, Yulin Li, 2021
  • Development of National Natural Product Standard Sample of Swertiamarin, Yulin Li, 2020
  • Separation of five flavonoids with similar polarity from Caragana korshinskii Kom. by preparative high speed counter-current chromatography with recycling and heart cut mode, Yulin Li, 2020
  • Optimization of ultrasonic extraction process of total flavonoids from Caragana korshinskii flowers by response surface methodology, Yulin Li, 2020
  • Theoretical Insights into Ester-Directed Reactions between Propiolates with 1,2-Benzisoxazoles by Au(I) Catalyst: 4+2-Annulation versus Michael-Type Products, Yulin Li, 2020
  • Mechanistic insights into the origin of substituent-directed product Z/E selectivity for gold-catalyzed 4+1-annulations of 1,4-diyn-3-ols with isoxazoles: A DFT study, Yulin Li, 2020
  • Evaluation of different pretreatment methods for determination of lead content in feed by graphite furnace atomic absorption spectrometry, Yulin Li, 2020
  • Efficient Separation of Five Flavonoids from Oxytropis falcata Bunge by High-Speed Counter-Current Chromatography and their Anticancer Activity, Yulin Li, 2020
  • Isolation and identification of three α-glucosidase inhibitors from Terminalia chebula Retz., Yulin Li, 2020
  • Analysis of Volatile Flavor Components in Yak Meat from Different Producing Areas of Qinghai Province by Head-Space Solid-Phase Microextraction and Gas Chromatography-Mass Spectrometry Technique, Yulin Li, 2020
  • Theoretical elucidation of the multi-functional synthetic methodology for switchable Ni(0)-catalyzed C-H allylations, alkenylations and dienylations with allenes, Yulin Li, 2020
  • A bright two-photon fluorescence probe with large stokes shift for deep tissue imaging of H2S during metabolism, Yulin Li, 2020
  • Analysis and Assessment of Bioactive Components of Potentilla fruticosa Leaves in Different Ecological Areas of Qinghai Province, Yulin Li, 2019
  • Development of Portable Speed Measuring Apparatus for Amylose and Amylopectin in Food, Yulin Li, 2019
Awards
  • National Science and Technology Innovation Award (2024): National Level
  • Qinghai Province Science Achievement Award (2023): Provincial Level
  • Outstanding Individual of the Public Technical Service Center of the Chinese Academy of Sciences (2020): Ministerial Level
  • Outstanding Professional and Technical Talent of Qinghai Province (2019): Provincial Level
  • First Prize for Key Technology Research and Application of Safety and Quality Control of Tibetan Medicine (2017): Ministerial Level
  • Outstanding Contribution Award for Western Scholars of the Chinese Academy of Sciences (2012): Ministerial Level
  • Youth Science and Technology Award of the Qinghai-Tibet Plateau (2009): Special Award
  • Second Prize for Comprehensive Utilization Technology and Product Research and Development of Nitraria Resources in the Qaidam Basin (2007): National Level
  • Second Prize of the President's Award of the Chinese Academy of Sciences (2007): Ministerial Level
  • First Prize for Comprehensive Utilization Technology and Product Research and Development of Nitraria Resources in the Qaidam Basin (2006): Provincial Level
  • Second Prize for Research and Industrialization of Total Flavonoids Technology of Sea Buckthorn (2006): Provincial Level
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