Professor | Hong Liu | Asia Growth Partners

Name	Hong Liu
Contact Information	hliu@simm.ac.cn
Language ability	Chinese, English
Province	Shanghai

Name

Hong Liu

Contact Information

hliu@simm.ac.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2005-01--2005-10 Visiting Scholar: University of Texas Medical Branch 2002-02--2002-10 Visiting Scholar: University of Texas Medical Branch 1999-09--2001-07 Postdoctoral: Shanghai Institute of Materia Medica, Chinese Academy of Sciences 1996-09--1999-07 Ph.D. in Science: China Pharmaceutical University 1993-09--1996-07 M.Sc. in Science: China Pharmaceutical University 1987-09--1991-07 B.Sc. in Science: China Pharmaceutical University
Work Experience	2006-07~Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher, Doctoral Supervisor 2005-01~2005-10 - University of Texas Medical Branch - Visiting Scholar 2002-02~2002-10 - University of Texas Medical Branch - Visiting Scholar 2001-09~2006-06 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Associate Researcher, Master's Supervisor 1999-09~2001-07 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Postdoctoral 1991-09~1993-08 - Shandong Xinhua Pharmaceutical Factory - Assistant Engineer
Awards	First Pudong New Area Science and Technology Elite (2023): City Level Zhu Li Yuehua Excellent Teacher Award (2022): Institute Level Shanghai Women Innovation Leading Talent (2022): Provincial Level 33rd Shanghai Excellent Invention Silver Award (2021): Provincial Level Shanghai Most Beautiful Science and Technology Worker (2021): Provincial Level 16th China Pharmaceutical Association Science and Technology Award, First Prize (2021): Provincial Level Advanced Individual in Fighting COVID-19 by China Democratic League (2020): Other Shanghai Pharmaceutical Science and Technology Award, First Prize (2020): Provincial Level 21st China Patent Excellence Award (2020): Ministerial Level 21st Wu Jieping-Paul Janssen Medical & Pharmaceutical Award (2020): Provincial Level Shanghai Science and Technology Progress Award, First Prize (2020): Provincial Level 14th China Youth Science and Technology Award, First Prize (2015): Ministerial Level Shanghai Pharmaceutical Science and Technology Award, First Prize (2015): City Level Zhu Li Yuehua Excellent Teacher Award, First Prize (2014): Ministerial Level 6th National Excellent Science and Technology Worker, First Prize (2014): National Level Shanghai Excellent Academic Leader, First Prize (2012): Provincial Level 8th China Young Women Scientist Award (2011): National Level Second Shanghai Branch of Chinese Academy of Sciences Outstanding (2010): Institute Level National Science Foundation for Distinguished Young Scholars (2010): National Level Sanofi-Aventis - Chinese Academy of Sciences Shanghai (2009): Institute Level National March 8th Red-Banner Pacesetter (2009): National Level National Natural Science Award, Second Prize (2007): National Level WuXi AppTec Life Chemistry Award, Third Prize (2007): Other Shanghai Youth Science and Technology Star Follow-up (2006): City Level Shanghai March 8th Red-Banner Pacesetter (2004): City Level Servier Youth Medicinal Chemistry Award by Chinese Pharmaceutical Association (2004): Other Chinese Chemical Society Youth Chemistry Award (2004): Other 9th Excellent Scientific Paper Award, First Prize (2003): Other Shanghai Youth Science and Technology Star (2003): City Level Shanghai Science and Technology Progress Award, First Prize (2003): City Level

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2005-01--2005-10 Visiting Scholar: University of Texas Medical Branch
2002-02--2002-10 Visiting Scholar: University of Texas Medical Branch
1999-09--2001-07 Postdoctoral: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
1996-09--1999-07 Ph.D. in Science: China Pharmaceutical University
1993-09--1996-07 M.Sc. in Science: China Pharmaceutical University
1987-09--1991-07 B.Sc. in Science: China Pharmaceutical University

Work Experience

2006-07~Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher, Doctoral Supervisor
2005-01~2005-10 - University of Texas Medical Branch - Visiting Scholar
2002-02~2002-10 - University of Texas Medical Branch - Visiting Scholar
2001-09~2006-06 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Associate Researcher, Master's Supervisor
1999-09~2001-07 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Postdoctoral
1991-09~1993-08 - Shandong Xinhua Pharmaceutical Factory - Assistant Engineer

Awards

First Pudong New Area Science and Technology Elite (2023): City Level
Zhu Li Yuehua Excellent Teacher Award (2022): Institute Level
Shanghai Women Innovation Leading Talent (2022): Provincial Level
33rd Shanghai Excellent Invention Silver Award (2021): Provincial Level
Shanghai Most Beautiful Science and Technology Worker (2021): Provincial Level
16th China Pharmaceutical Association Science and Technology Award, First Prize (2021): Provincial Level
Advanced Individual in Fighting COVID-19 by China Democratic League (2020): Other
Shanghai Pharmaceutical Science and Technology Award, First Prize (2020): Provincial Level
21st China Patent Excellence Award (2020): Ministerial Level
21st Wu Jieping-Paul Janssen Medical & Pharmaceutical Award (2020): Provincial Level
Shanghai Science and Technology Progress Award, First Prize (2020): Provincial Level
14th China Youth Science and Technology Award, First Prize (2015): Ministerial Level
Shanghai Pharmaceutical Science and Technology Award, First Prize (2015): City Level
Zhu Li Yuehua Excellent Teacher Award, First Prize (2014): Ministerial Level
6th National Excellent Science and Technology Worker, First Prize (2014): National Level
Shanghai Excellent Academic Leader, First Prize (2012): Provincial Level
8th China Young Women Scientist Award (2011): National Level
Second Shanghai Branch of Chinese Academy of Sciences Outstanding (2010): Institute Level
National Science Foundation for Distinguished Young Scholars (2010): National Level
Sanofi-Aventis - Chinese Academy of Sciences Shanghai (2009): Institute Level
National March 8th Red-Banner Pacesetter (2009): National Level
National Natural Science Award, Second Prize (2007): National Level
WuXi AppTec Life Chemistry Award, Third Prize (2007): Other
Shanghai Youth Science and Technology Star Follow-up (2006): City Level
Shanghai March 8th Red-Banner Pacesetter (2004): City Level
Servier Youth Medicinal Chemistry Award by Chinese Pharmaceutical Association (2004): Other
Chinese Chemical Society Youth Chemistry Award (2004): Other
9th Excellent Scientific Paper Award, First Prize (2003): Other
Shanghai Youth Science and Technology Star (2003): City Level
Shanghai Science and Technology Progress Award, First Prize (2003): City Level

Areas of Focus	Medicinal Chemistry Drug Design
Publications	Rapid Access to Polysubstituted Tetrahydrocarbazol-4-ones via Sequential Selective C-H Functionalization from N-Nitrosoanilines, 7th Author, 2023 Rh(III)-Catalyzed Successive C-H Activations of 2-Phenyl-3H-indoles and Cyclization Cascades to Construct Highly Fused Indole Heteropolycycles, 5th Author, 2023 Research Progress on Structural Optimization on the Lipid-Soluble Ingredients of Salvia miltiorrhiza, 3rd Author, 2023 The synthesis of spirocyclopropane skeletons enabled by Rh(III)-catalyzed enantioselective C-H activation/4+ 2 annulation, 12th Author, 2023 Synthesis of maleimide-braced peptide macrocycles and their potential anti-SARS-CoV-2 mechanisms, 14th Author, 2023 Controlled sequential in situ self-assembly and disassembly of a fluorogenic cisplatin prodrug for cancer theranostics, 15th Author, 2023 Structural Optimization of Fibroblast Growth Factor Receptor Inhibitors for Treating Solid Tumors, 17th Author, 2023 Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4), 17th Author, 2023 Discovery, synthesis and mechanism study of 2,3,5-substituted 1,2,4-thiadiazoles as covalent inhibitors targeting 3C-Like protease of SARS-CoV-2, 16th Author, 2023 Construction of Vinyl-Substituted N-Heterocycles via Rh(III)- Catalyzed C-H Functionalization/Annulation of Pyrazolidinones, 5th Author, 2023 Smart Nanosensitizers for Activatable Sono-Photodynamic Immunotherapy of Tumors by Redox-Controlled Disassembly, 14th Author, 2023 Cobalt(II)-Catalyzed C(sp3)-C(sp3) Coupling for the Direct Stereoselective Synthesis of 2-Deoxy-C-glycosides from Glycals., 6th Author, 2023 Versatile Pd(II) Complexes of Chiral Proline-Derived Ligand: Application for Dynamic Kinetic Resolution of β-Amino Acids and Their Antibacterial Activities., 7th Author, 2023

Areas of Focus

Medicinal Chemistry
Drug Design

Publications

Rapid Access to Polysubstituted Tetrahydrocarbazol-4-ones via Sequential Selective C-H Functionalization from N-Nitrosoanilines, 7th Author, 2023
Rh(III)-Catalyzed Successive C-H Activations of 2-Phenyl-3H-indoles and Cyclization Cascades to Construct Highly Fused Indole Heteropolycycles, 5th Author, 2023
Research Progress on Structural Optimization on the Lipid-Soluble Ingredients of Salvia miltiorrhiza, 3rd Author, 2023
The synthesis of spirocyclopropane skeletons enabled by Rh(III)-catalyzed enantioselective C-H activation/4+ 2 annulation, 12th Author, 2023
Synthesis of maleimide-braced peptide macrocycles and their potential anti-SARS-CoV-2 mechanisms, 14th Author, 2023
Controlled sequential in situ self-assembly and disassembly of a fluorogenic cisplatin prodrug for cancer theranostics, 15th Author, 2023
Structural Optimization of Fibroblast Growth Factor Receptor Inhibitors for Treating Solid Tumors, 17th Author, 2023
Ligand recognition mechanism of the human relaxin family peptide receptor 4 (RXFP4), 17th Author, 2023
Discovery, synthesis and mechanism study of 2,3,5-substituted 1,2,4-thiadiazoles as covalent inhibitors targeting 3C-Like protease of SARS-CoV-2, 16th Author, 2023
Construction of Vinyl-Substituted N-Heterocycles via Rh(III)- Catalyzed C-H Functionalization/Annulation of Pyrazolidinones, 5th Author, 2023
Smart Nanosensitizers for Activatable Sono-Photodynamic Immunotherapy of Tumors by Redox-Controlled Disassembly, 14th Author, 2023
Cobalt(II)-Catalyzed C(sp3)-C(sp3) Coupling for the Direct Stereoselective Synthesis of 2-Deoxy-C-glycosides from Glycals., 6th Author, 2023
Versatile Pd(II) Complexes of Chiral Proline-Derived Ligand: Application for Dynamic Kinetic Resolution of β-Amino Acids and Their Antibacterial Activities., 7th Author, 2023

Drug Discovery Pharmaceuticals Organic Chemistry Synthesis Bioactivity Molecular Design Therapeutics Chemical Biology Pharmacology Biochemistry

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