Areas of Focus
- Microbial natural product discovery, biosynthesis, and synthetic biology
Work Experience
- 2022-01~Present - Institute of Microbiology, Chinese Academy of Sciences - Researcher
- 2019-08~2022-01 - Institute of Microbiology, Chinese Academy of Sciences - Project Researcher
- 2014-02~2019-08 - The Scripps Research Institute - Postdoctoral Researcher
Academic Background & Achievements
- 2008-09--2014-01 PhD: University of Chinese Academy of Sciences
- 2004-09--2008-07 Bachelor: China University of Mining and Technology (Beijing)
Publications
- Confirmation of the stereochemistry of spiroviolene, Yao Kong, Yuanning Liu, Kaibiao Wang, Tao Wang, Chen Wang, Ben Ai, Hongli Jia, Guohui Pan, Min Yin, Zhengren Xu, 2024
- Cofactor-independent C–C bond cleavage reactions catalyzed by the AlpJ family of oxygenases in atypical angucycline biosynthesis, Jinmin Gao, Liyuan Li, Shijie Shen, Guomin Ai, Bin Wang, Fang Guo, Tongjian Yang, Hui Han, Zhengren Xu, Guohui Pan, Keqiang Fan, 2024
- Discrete Acyltransferases and Thioesterases in Iso-Migrastatin and Lactimidomycin Biosynthesis, Andrew D Steele, Hui Jiang, Guohui Pan, Si-Kyu Lim, Edward Kalkreuter, Jianhua Ju, Thomas Kwong, Scott Rajski, Ben Shen, 2024
- Tetracycline family natural products: discovery, biosynthesis and engineering, Haiyan Wang, Lijun Wang, Keqiang Fan, Guohui Pan, 2022
- Molecular mechanism of GylR-mediated regulation of glycerol metabolism in Streptomyces clavuligerus NRRL 3585, Zhang, Chaobo, Zhao, Youbao, Li, Zilong, Wang, Weishan, Huang, Ying, Pan, Guohui, Fan, Keqiang, 2022
- (S)-3-aminopiperidine-2,6-dione is a biosynthetic intermediate of microbial blue-pigments indigoidine, 张志龙, 李鹏伟, 王敏, 张雁, 吴边, 陶勇, 潘国辉, 陈义华, 2022
- Dynamic Control Strategy to Produce Riboflavin with Lignocellulose Hydrolysate in the Thermophile Geobacillus thermoglucosidasius, Wang, Junyang, Li, Zilong, Wang, Weishan, Pang, Shen, Yao, Yongpeng, Yuan, Fang, Wang, Huizhuan, Xu, Zhen, Pan, Guohui, Liu, Zihe, Chen, Yihua, Fan, Keqiang, 2022
- The Richness and Diversity of Catalases in Bacteria, Yuan, Fang, Yin, Shouliang, Xu, Yang, Xiang, Lijun, Wang, Haiyan, Li, Zilong, Fan, Keqiang, Pan, Guohui, 2021
- 基于生物信息学分析从Streptomyces albofaciens JCM 4342中发现2，3-二羟基苯甲酸酯-L-丝氨酸脱水三聚体和二聚体天然产物, 王立军, 范可强, 王海燕, 胡会涛, 向丽军, 艾国民, 潘国辉, 2021
- Thiocysteine lyases as polyketide synthase domains installing hydropersulfide into natural products and a hydropersulfide methyltransferase, Meng, Song, Steele, Andrew D, Yan, Wei, Pan, Guohui, Kalkreuter, Edward, Liu, YuChen, Xu, Zhengren, Shen, Ben, 2021
- 基于生物信息学分析从Streptomyces albofaciens JCM 4342中发现2，3-二羟基苯甲酸酯-L-丝氨酸脱水三聚体和二聚体天然产物（英文）, 王立军, 范可强, 王海燕, 胡会涛, 向丽军, 艾国民, 潘国辉, 2021
- A Versatile Transcription-Translation in One Approach for Activation of Cryptic Biosynthetic Gene Clusters, Zhang, Qian, Ren, JinWei, Wang, Weishan, Zhai, Jian, Yang, Jing, Liu, Ning, Huang, Ying, Chen, Yihua, Pan, Guohui, Fan, Keqiang, 2020
- Targeting Bacterial Genomes for Natural Product Discovery, Kalkreuter, Edward, Pan, Guohui, Cepeda, Alexis J, Shen, Ben, 2020
- The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research, McAlpine, James B, Chen, ShaoNong, Kutateladze, Andrei, MacMillan, John B, Appendino, Giovanni, Barison, Andersson, Beniddir, Mehdi A, Biavatti, Maique W, Bluml, Stefan, Boufridi, Asmaa, Butler, Mark S, Capon, Robert J, Choi, Young H, Coppage, David, Crews, Phillip, Crimmins, Michael T, Csete, Marie, Dewapriya, Pradeep, Egan, Joseph M, Garson, Mary J, GentaJouve, Gregory, Gerwick, William H, Gross, Harald, Harper, Mary Kay, Hermanto, Precilia, Hook, James M, Hunter, Luke, Jeannerat, Damien, Ji, NaiYun, Johnson, Tyler A, Kingston, David G I, Koshino, Hiroyuki, Lee, HsiauWei, Lewin, Guy, Li, Jie, Linington, Roger G, Liu, Miaomiao, McPhail, Kerry L, Molinski, Tadeusz F, Moore, Bradley S, Nam, JooWon, Neupane, Ram P, Niemitz, Matthias, Nuzillard, JeanMarc, Oberlies, Nicholas H, Ocampos, Fernanda M M, Pan, Guohui, Quinn, Ronald J, Reddy, D Sai, Renault, JeanHugues, RiveraChavez, Jose, Robien, Wolfgang, Saunders, Carla M, Schmidt, Thomas J, Seger, Christoph, Shen, Ben, Steinbeck, Christoph, , 2019
- P450-Catalyzed Tailoring Steps in Leinamycin Biosynthesis Featuring Regio- and Stereoselective Hydroxylations and Substrate Promiscuities, Kwong, Thomas, Ma, Ming, Pan, Guohui, Hindra, Yang, Dong, Yang, Chunying, Lohman, Jeremy R, Rudolf, Jeffrey D, Cleveland, John L, Shen, Ben, 2018
- Discovery and Characterization of 1-Aminocyclopropane-1-carboxylic Acid Synthase of Bacterial Origin, Xu, Zhengren, Pan, Guohui, Zhou, Hao, Shen, Ben, 2018
- Engineered jadomycin analogues with altered sugar moieties revealing JadS as a substrate flexible O-glycosyltransferase, Li, Liyuan, Pan, Guohui, Zhu, Xifen, Fan, Keqiang, Gao, Wubin, Ai, Guomin, Ren, Jinwei, Shi, Mingxin, Olano, Carlos, Salas, Jose A, Yang, Keqian, 2017
- Discovery of the leinamycin family of natural products by mining actinobacterial genomes, Pan, Guohui, Xu, Zhengren, Guo, Zhikai, Hindra, Ma, Ming, Yang, Dong, Zhou, Hao, Gansemans, Yannick, Zhu, Xiangcheng, Huang, Yong, Zhao, LiXing, Jiang, Yi, Cheng, Jinhua, Van Nieuwerburgh, Filip, Suh, JooWon, Duan, Yanwen, Shen, Ben, 2017
- Structure and Function of a C-C Bond Cleaving Oxygenase in Atypical Angucycline Biosynthesis, Pan, Guohui, Gao, Xiaoqin, Fan, Keqiang, Liu, Junlin, Meng, Bing, Gao, Jinmin, Wang, Bin, Zhang, Chaobo, Han, Hui, Ai, Guomin, Chen, Yihua, Wu, Dong, Liu, ZhiJie, Yang, Keqian, 2017
- New isofuranonaphthoquinones and isoindolequinones from Streptomyces sp CB01883, Guo, Zhikai, Pan, Guohui, Xu, Zhengren, Yang, Dong, Hindra, Zhu, Xiangcheng, Huang, Yong, Zhao, LiXing, Jiang, Yi, Duan, Yanwen, Shen, Ben, 2017
- Characterization of LnmO as a pathway-specific Crp/Fnr-type positive regulator for leinamycin biosynthesis in Streptomyces atroolivaceus and its application for titer improvement, Huang, Yong, Yang, Dong, Pan, Guohui, Tang, GongLi, Shen, Ben, 2016
- Overproduction of lactimidomycin by cross-overexpression of genes encoding Streptomyces antibiotic regulatory proteins, Zhang, Bo, Yang, Dong, Yan, Yijun, Pan, Guohui, Xiang, Wensheng, Shen, Ben, 2016
- Characterization of the Ketosynthase and Acyl Carrier Protein Domains at the LnmI Nonribosomal Peptide Synthetase-Polyketide Synthase Interface for Leinamycin Biosynthesis, Huang, Yong, Tang, GongLi, Pan, Guohui, Chang, ChinYuan, Shen, Ben, 2016
- Minimum Information about a Biosynthetic Gene cluster, Medema, Marnix H, Kottmann, Renzo, Yilmaz, Pelin, Cummings, Matthew, Biggins, John B, Blin, Kai, de Bruijn, Irene, Chooi, Yit Heng, Claesen, Jan, Coates, R Cameron, CruzMorales, Pablo, Duddela, Srikanth, Duesterhus, Stephanie, Edwards, Daniel J, Fewer, David P, Garg, Neha, Geiger, Christoph, GomezEscribano, Juan Pablo, Greule, Anja, Hadjithomas, Michalis, Haines, Anthony S, Helfrich, Eric J N, Hillwig, Matthew L, Ishida, Keishi, Jones, Adam C, Jones, Carla S, Jungmann, Katrin, Kegler, Carsten, Kim, Hyun Uk, Koetter, Peter, Krug, Daniel, Masschelein, Joleen, Melnik, Alexey V, Mantovani, Simone M, Monroe, Emily A, Moore, Marcus, Moss, Nathan, Nuetzmann, HansWilhelm, Pan, Guohui, Pati, Amrita, Petras, Daniel, Reen, F Jerry, Rosconi, Federico, Rui, Zhe, Tian, Zhenhua, Tobias, Nicholas J, Tsunematsu, Yuta, Wiemann, Philipp, Wyckoff, Elizabeth, Yan, Xiaohui, Yim, Grace, Yu, Fengan, Xie, Yunchang, Aigle, Bertrand, Apel, Alexander K, Balibar, Carl J, Balskus, Emily P, BaronaGomez, Francisco, B
