Professor | Lin Baixue | Asia Growth Partners

Name	Lin Baixue
Contact Information	linbx@im.ac.cn
Language ability	Chinese, English
Province	Beijing

Name

Lin Baixue

Contact Information

linbx@im.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2006-09--2010-06 PhD: Fujian Agriculture and Forestry University 2000-09--2003-07 Master's: South China University of Technology 1996-09--2000-07 Bachelor's: South China University of Technology
Work Experience	2021-11~Present - Institute of Microbiology, Chinese Academy of Sciences - Project Researcher, CAS Distinguished Backbone 2016-08~2016-10 - University of Delaware, USA - Visiting Scholar 2015-09~2021-11 - Institute of Microbiology, Chinese Academy of Sciences - Associate Researcher 2013-03~2015-09 - Institute of Microbiology, Chinese Academy of Sciences - Assistant Researcher 2010-09~2013-03 - Institute of Microbiology, Chinese Academy of Sciences - Postdoctoral Researcher 2006-09~2010-06 - Fujian Agriculture and Forestry University - PhD 2003-07~2010-08 - Fujian Agriculture and Forestry University - Assistant Researcher 2000-09~2003-07 - South China University of Technology - Master's 1996-09~2000-07 - South China University of Technology - Bachelor's
Awards	China Light Industry Federation Science and Technology Progress Award, Second Prize, Ministerial Level, 2020

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2006-09--2010-06 PhD: Fujian Agriculture and Forestry University
2000-09--2003-07 Master's: South China University of Technology
1996-09--2000-07 Bachelor's: South China University of Technology

Work Experience

2021-11~Present - Institute of Microbiology, Chinese Academy of Sciences - Project Researcher, CAS Distinguished Backbone
2016-08~2016-10 - University of Delaware, USA - Visiting Scholar
2015-09~2021-11 - Institute of Microbiology, Chinese Academy of Sciences - Associate Researcher
2013-03~2015-09 - Institute of Microbiology, Chinese Academy of Sciences - Assistant Researcher
2010-09~2013-03 - Institute of Microbiology, Chinese Academy of Sciences - Postdoctoral Researcher
2006-09~2010-06 - Fujian Agriculture and Forestry University - PhD
2003-07~2010-08 - Fujian Agriculture and Forestry University - Assistant Researcher
2000-09~2003-07 - South China University of Technology - Master's
1996-09~2000-07 - South China University of Technology - Bachelor's

Awards

China Light Industry Federation Science and Technology Progress Award, Second Prize, Ministerial Level, 2020

Areas of Focus	Synthetic Biology Microbial Metabolic Engineering Biocatalysis
Publications	A citric acid cycle-deficient Escherichia coli as an efficient chassis for aerobic fermentations., Nature Communications, 2024 Improved methylation in E. coli via an efficient methyl supply system driven by betaine, METABOLIC ENGINEERING, 2022 Bioinspired Anti-Icing Hydrogel Enabled by Ice-Nucleating Protein, CCS Chemistry, 2022 Highly Efficient Production of Menaquinone-7 from Glucose by Metabolically Engineered Escherichia coli, ACS SYNTHETIC BIOLOGY, 2021 Reconstitution of the Ornithine Cycle with Arginine:Glycine Amidinotransferase to Engineer Escherichia coli into an Efficient Whole-Cell Catalyst of Guanidinoacetate, ACS SYNTHETIC BIOLOGY, 2020 Bioretrosynthesis of Functionalized N-Heterocycles from Glucose via One-Pot Tandem Collaborations of Designed Microbes, ADVANCED SCIENCE, 2020 Metabolic engineering of Escherichia coli for efficient production of l-alanyl-l-glutamine, MICROBIAL CELL FACTORIES, 2020 Menaquinone-7 production in engineered Escherichia coli, WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2020 Metabolic engineering of Escherichia coli for production of L-aspartate and its derivative beta-alanine with high stoichiometric yield, METABOLIC ENGINEERING, 2019 Metabolic engineering for efficient supply of acetyl-CoA from different carbon sources in Escherichia coli, MICROBIAL CELL FACTORIES, 2019 Comparison of synthesis of carbamoyl phosphate through different pathway in Escherichia coli, 微生物学通报, 2019 Engineering deacetoxycephalosporin C synthase as a catalyst for the bioconversion of penicillins, JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 2017 Synthesis of Sialic Acids, Their Derivatives, and Analogs by Using a Whole-Cell Catalyst, CHEMISTRY-A EUROPEAN JOURNAL, 2017 Synthesis of sialic acids, their derivatives and analogues using a whole-cell catalyst., Chemistry-A European Journal, 2017 Cofactor self-sufficient whole-cell biocatalysts for the production of 2-phenylethanol, METABOLIC ENGINEERING, 2017 Engineering deacetoxycephalosporin C synthase as a catalyst for the bioconversion of penicillins., Journal of Industrial Microbiology & Biotechnology, 2017 Whole-cell biocatalysts by design, MICROBIAL CELL FACTORIES, 2017 Polysialic acid biosynthesis and production in Escherichia coli: current state and perspectives, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2016 Enhanced production of polysialic acid by metabolic engineering of Escherichia coli, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2015 Reconstitution of TCA cycle with DAOCS to engineer E.coli into an efficient whole cell catalyst of penicillin G, ProcNatlAcadSci USA, 2015 Improving isoprene production by engineered heterologous mevalonate pathway in Escherichia coli, 生物工程学报, 2015 Reconstitution of TCA cycle with DAOCS to engineer Escherichia coli into an efficient whole cell catalyst of penicillin G, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015 Optimization of whole-cell biocatalysis for phenylacetyl-7-aminodeacetoxycephalosporanic acid production, 生物工程学报, 2014 Enhanced production of N-acetyl-D-neuraminic acid by multi-approach whole-cell biocatalyst, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2013 全细胞催化生产N-乙酰神经氨酸的条件优化, 微生物学通报, 2013 Characterization of a Recombinant Thermostable Xylanase from Hot Spring Thermophilic Geobacillus sp TC-W7, JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2012

Areas of Focus

Synthetic Biology
Microbial Metabolic Engineering
Biocatalysis

Publications

A citric acid cycle-deficient Escherichia coli as an efficient chassis for aerobic fermentations., Nature Communications, 2024
Improved methylation in E. coli via an efficient methyl supply system driven by betaine, METABOLIC ENGINEERING, 2022
Bioinspired Anti-Icing Hydrogel Enabled by Ice-Nucleating Protein, CCS Chemistry, 2022
Highly Efficient Production of Menaquinone-7 from Glucose by Metabolically Engineered Escherichia coli, ACS SYNTHETIC BIOLOGY, 2021
Reconstitution of the Ornithine Cycle with Arginine:Glycine Amidinotransferase to Engineer Escherichia coli into an Efficient Whole-Cell Catalyst of Guanidinoacetate, ACS SYNTHETIC BIOLOGY, 2020
Bioretrosynthesis of Functionalized N-Heterocycles from Glucose via One-Pot Tandem Collaborations of Designed Microbes, ADVANCED SCIENCE, 2020
Metabolic engineering of Escherichia coli for efficient production of l-alanyl-l-glutamine, MICROBIAL CELL FACTORIES, 2020
Menaquinone-7 production in engineered Escherichia coli, WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2020
Metabolic engineering of Escherichia coli for production of L-aspartate and its derivative beta-alanine with high stoichiometric yield, METABOLIC ENGINEERING, 2019
Metabolic engineering for efficient supply of acetyl-CoA from different carbon sources in Escherichia coli, MICROBIAL CELL FACTORIES, 2019
Comparison of synthesis of carbamoyl phosphate through different pathway in Escherichia coli, 微生物学通报, 2019
Engineering deacetoxycephalosporin C synthase as a catalyst for the bioconversion of penicillins, JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 2017
Synthesis of Sialic Acids, Their Derivatives, and Analogs by Using a Whole-Cell Catalyst, CHEMISTRY-A EUROPEAN JOURNAL, 2017
Synthesis of sialic acids, their derivatives and analogues using a whole-cell catalyst., Chemistry-A European Journal, 2017
Cofactor self-sufficient whole-cell biocatalysts for the production of 2-phenylethanol, METABOLIC ENGINEERING, 2017
Engineering deacetoxycephalosporin C synthase as a catalyst for the bioconversion of penicillins., Journal of Industrial Microbiology & Biotechnology, 2017
Whole-cell biocatalysts by design, MICROBIAL CELL FACTORIES, 2017
Polysialic acid biosynthesis and production in Escherichia coli: current state and perspectives, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2016
Enhanced production of polysialic acid by metabolic engineering of Escherichia coli, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2015
Reconstitution of TCA cycle with DAOCS to engineer E.coli into an efficient whole cell catalyst of penicillin G, ProcNatlAcadSci USA, 2015
Improving isoprene production by engineered heterologous mevalonate pathway in Escherichia coli, 生物工程学报, 2015
Reconstitution of TCA cycle with DAOCS to engineer Escherichia coli into an efficient whole cell catalyst of penicillin G, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015
Optimization of whole-cell biocatalysis for phenylacetyl-7-aminodeacetoxycephalosporanic acid production, 生物工程学报, 2014
Enhanced production of N-acetyl-D-neuraminic acid by multi-approach whole-cell biocatalyst, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2013
全细胞催化生产N-乙酰神经氨酸的条件优化, 微生物学通报, 2013
Characterization of a Recombinant Thermostable Xylanase from Hot Spring Thermophilic Geobacillus sp TC-W7, JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2012

Synthetic Biology Genetic Engineering Metabolic Pathways Microbial Engineering Biocatalysis Enzyme Engineering Biotechnology Metabolic Engineering Microbial Metabolism Bioengineering

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