Areas of Focus
- Synthetic Biology
- Microbial Metabolic Engineering
- Biocatalysis
Work Experience
- 2021-11~Present - Institute of Microbiology, Chinese Academy of Sciences - Project Researcher, CAS Distinguished Backbone
- 2016-08~2016-10 - University of Delaware, USA - Visiting Scholar
- 2015-09~2021-11 - Institute of Microbiology, Chinese Academy of Sciences - Associate Researcher
- 2013-03~2015-09 - Institute of Microbiology, Chinese Academy of Sciences - Assistant Researcher
- 2010-09~2013-03 - Institute of Microbiology, Chinese Academy of Sciences - Postdoctoral Researcher
- 2006-09~2010-06 - Fujian Agriculture and Forestry University - PhD
- 2003-07~2010-08 - Fujian Agriculture and Forestry University - Assistant Researcher
- 2000-09~2003-07 - South China University of Technology - Master's
- 1996-09~2000-07 - South China University of Technology - Bachelor's
Academic Background & Achievements
- 2006-09--2010-06 PhD: Fujian Agriculture and Forestry University
- 2000-09--2003-07 Master's: South China University of Technology
- 1996-09--2000-07 Bachelor's: South China University of Technology
Publications
- A citric acid cycle-deficient Escherichia coli as an efficient chassis for aerobic fermentations., Nature Communications, 2024
- Improved methylation in E. coli via an efficient methyl supply system driven by betaine, METABOLIC ENGINEERING, 2022
- Bioinspired Anti-Icing Hydrogel Enabled by Ice-Nucleating Protein, CCS Chemistry, 2022
- Highly Efficient Production of Menaquinone-7 from Glucose by Metabolically Engineered Escherichia coli, ACS SYNTHETIC BIOLOGY, 2021
- Reconstitution of the Ornithine Cycle with Arginine:Glycine Amidinotransferase to Engineer Escherichia coli into an Efficient Whole-Cell Catalyst of Guanidinoacetate, ACS SYNTHETIC BIOLOGY, 2020
- Bioretrosynthesis of Functionalized N-Heterocycles from Glucose via One-Pot Tandem Collaborations of Designed Microbes, ADVANCED SCIENCE, 2020
- Metabolic engineering of Escherichia coli for efficient production of l-alanyl-l-glutamine, MICROBIAL CELL FACTORIES, 2020
- Menaquinone-7 production in engineered Escherichia coli, WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2020
- Metabolic engineering of Escherichia coli for production of L-aspartate and its derivative beta-alanine with high stoichiometric yield, METABOLIC ENGINEERING, 2019
- Metabolic engineering for efficient supply of acetyl-CoA from different carbon sources in Escherichia coli, MICROBIAL CELL FACTORIES, 2019
- Comparison of synthesis of carbamoyl phosphate through different pathway in Escherichia coli, 微生物学通报, 2019
- Engineering deacetoxycephalosporin C synthase as a catalyst for the bioconversion of penicillins, JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 2017
- Synthesis of Sialic Acids, Their Derivatives, and Analogs by Using a Whole-Cell Catalyst, CHEMISTRY-A EUROPEAN JOURNAL, 2017
- Synthesis of sialic acids, their derivatives and analogues using a whole-cell catalyst., Chemistry-A European Journal, 2017
- Cofactor self-sufficient whole-cell biocatalysts for the production of 2-phenylethanol, METABOLIC ENGINEERING, 2017
- Engineering deacetoxycephalosporin C synthase as a catalyst for the bioconversion of penicillins., Journal of Industrial Microbiology & Biotechnology, 2017
- Whole-cell biocatalysts by design, MICROBIAL CELL FACTORIES, 2017
- Polysialic acid biosynthesis and production in Escherichia coli: current state and perspectives, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2016
- Enhanced production of polysialic acid by metabolic engineering of Escherichia coli, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2015
- Reconstitution of TCA cycle with DAOCS to engineer E.coli into an efficient whole cell catalyst of penicillin G, ProcNatlAcadSci USA, 2015
- Improving isoprene production by engineered heterologous mevalonate pathway in Escherichia coli, 生物工程学报, 2015
- Reconstitution of TCA cycle with DAOCS to engineer Escherichia coli into an efficient whole cell catalyst of penicillin G, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015
- Optimization of whole-cell biocatalysis for phenylacetyl-7-aminodeacetoxycephalosporanic acid production, 生物工程学报, 2014
- Enhanced production of N-acetyl-D-neuraminic acid by multi-approach whole-cell biocatalyst, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2013
- 全细胞催化生产N-乙酰神经氨酸的条件优化, 微生物学通报, 2013
- Characterization of a Recombinant Thermostable Xylanase from Hot Spring Thermophilic Geobacillus sp TC-W7, JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2012
Awards
- China Light Industry Federation Science and Technology Progress Award, Second Prize, Ministerial Level, 2020