Professor | Hui Tao | Asia Growth Partners

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Name	Hui Tao
Contact Information	thui@whu.edu.cn
Language ability	Chinese, English
Province	Hubei

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Name

Hui Tao

Contact Information

thui@whu.edu.cn

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	2013.09 - 2018.06 PhD: Wuhan University, School of Pharmaceutical Sciences, Supervisors: Prof. Zixin Deng, Prof. Tiangang Liu 2009.09 - 2013.06 Bachelor: Wuhan University, School of Pharmaceutical Sciences, Supervisor: Prof. Tiangang Liu
Work Experience	2023.02 - Present: Wuhan University, School of Pharmaceutical Sciences, Professor, Doctoral Supervisor 2022.08 - 2023.02: University of Tokyo, Japan, Project Researcher, Collaborative Supervisor: Prof. Hiroaki Suga 2018.10 - 2022.08: University of Tokyo, Japan, JSPS Special Research Fellow, Collaborative Supervisor: Prof. Ikuro Abe 2017.02 - 2017.03: Washington University in St. Louis, USA, Visiting Student, Collaborative Supervisor: Prof. Yinjie Tang 2016.05 - 2016.10: Chalmers University of Technology, Sweden, Visiting Student, Collaborative Supervisor: Prof. Jens Nielsen
Awards	JSPS Special Research Fellow (2018) Wuhan University Medical Outstanding Contribution Award (2016) Wuhan University Graduate Academic Innovation Award (2016)

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

2013.09 - 2018.06 PhD: Wuhan University, School of Pharmaceutical Sciences, Supervisors: Prof. Zixin Deng, Prof. Tiangang Liu
2009.09 - 2013.06 Bachelor: Wuhan University, School of Pharmaceutical Sciences, Supervisor: Prof. Tiangang Liu

Work Experience

2023.02 - Present: Wuhan University, School of Pharmaceutical Sciences, Professor, Doctoral Supervisor
2022.08 - 2023.02: University of Tokyo, Japan, Project Researcher, Collaborative Supervisor: Prof. Hiroaki Suga
2018.10 - 2022.08: University of Tokyo, Japan, JSPS Special Research Fellow, Collaborative Supervisor: Prof. Ikuro Abe
2017.02 - 2017.03: Washington University in St. Louis, USA, Visiting Student, Collaborative Supervisor: Prof. Yinjie Tang
2016.05 - 2016.10: Chalmers University of Technology, Sweden, Visiting Student, Collaborative Supervisor: Prof. Jens Nielsen

Awards

JSPS Special Research Fellow (2018)
Wuhan University Medical Outstanding Contribution Award (2016)
Wuhan University Graduate Academic Innovation Award (2016)

Areas of Focus	Synthetic Biology of Active Natural Products Enzyme Catalysis Mechanisms and Engineering
Publications	Discovery of non-squalene triterpenes, Hui Tao et al., 2022 Stereoselectivity and substrate specificity of the Fe (II)/α-ketoglutarate-dependent oxygenase TqaL, Hui Tao et al., 2022 Molecular insights into the unusually promiscuous and catalytically versatile Fe (II)/α-ketoglutarate-dependent oxygenase SptF, Hui Tao et al., 2022 One polyketide synthase, two distinct products: trans-acting enzyme-controlled product divergence in calbistrin biosynthesis, Hui Tao et al., 2021 Harnessing Fe(II)/α-ketoglutarate-dependent oxygenases for structural diversification of fungal meroterpenoids, Hui Tao et al., 2022 Enzymology and biosynthesis of the orsellinic acid derived medicinal meroterpenoids, Hui Tao et al., 2021 Oxidative modification of free-standing amino acids by Fe (II)/αKG-dependent oxygenases, Hui Tao et al., 2022 Increasing the heterologous production of spinosad in Streptomyces albus J1074 by regulating biosynthesis of its polyketide skeleton, Hui Tao et al., 2021 Strategies for enhancing the yield of the potent insecticide spinosad in actinomycetes, Hui Tao et al., 2019 Absolute quantification of proteins in the fatty acid biosynthetic pathway using protein standard absolute quantification, Hui Tao et al., 2016 Metabolic engineering of microbes for branched-chain biodiesel production with low-temperature property, Hui Tao et al., 2015 Rational engineering of the nonheme iron-and 2-oxoglutarate-dependent oxygenase SptF, Hui Tao et al., 2022 Structural diversification of andiconin-derived natural products by α-ketoglutarate-dependent dioxygenases, Hui Tao et al., 2020 Heterologous biosynthesis of spinosad: an omics-guided large polyketide synthase gene cluster reconstitution in streptomyces, Hui Tao et al. Production of taxadiene by engineering of mevalonate pathway in Escherichia coli and endophytic fungus Alternaria alternata TPF6, Hui Tao et al., 2017

Areas of Focus

Synthetic Biology of Active Natural Products
Enzyme Catalysis Mechanisms and Engineering

Publications

Discovery of non-squalene triterpenes, Hui Tao et al., 2022
Stereoselectivity and substrate specificity of the Fe (II)/α-ketoglutarate-dependent oxygenase TqaL, Hui Tao et al., 2022
Molecular insights into the unusually promiscuous and catalytically versatile Fe (II)/α-ketoglutarate-dependent oxygenase SptF, Hui Tao et al., 2022
One polyketide synthase, two distinct products: trans-acting enzyme-controlled product divergence in calbistrin biosynthesis, Hui Tao et al., 2021
Harnessing Fe(II)/α-ketoglutarate-dependent oxygenases for structural diversification of fungal meroterpenoids, Hui Tao et al., 2022
Enzymology and biosynthesis of the orsellinic acid derived medicinal meroterpenoids, Hui Tao et al., 2021
Oxidative modification of free-standing amino acids by Fe (II)/αKG-dependent oxygenases, Hui Tao et al., 2022
Increasing the heterologous production of spinosad in Streptomyces albus J1074 by regulating biosynthesis of its polyketide skeleton, Hui Tao et al., 2021
Strategies for enhancing the yield of the potent insecticide spinosad in actinomycetes, Hui Tao et al., 2019
Absolute quantification of proteins in the fatty acid biosynthetic pathway using protein standard absolute quantification, Hui Tao et al., 2016
Metabolic engineering of microbes for branched-chain biodiesel production with low-temperature property, Hui Tao et al., 2015
Rational engineering of the nonheme iron-and 2-oxoglutarate-dependent oxygenase SptF, Hui Tao et al., 2022
Structural diversification of andiconin-derived natural products by α-ketoglutarate-dependent dioxygenases, Hui Tao et al., 2020
Heterologous biosynthesis of spinosad: an omics-guided large polyketide synthase gene cluster reconstitution in streptomyces, Hui Tao et al.
Production of taxadiene by engineering of mevalonate pathway in Escherichia coli and endophytic fungus Alternaria alternata TPF6, Hui Tao et al., 2017

Synthetic Biology Gene Mining Biosynthesis Bioinformatics Enzyme Engineering Metabolic Pathways High-Value Chemicals Microbial Synthesis Biocatalysis Natural Product Derivatives

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