2000-10--2005-02 PhD: Dalhousie University, Life Sciences
1996-09--1999-07 MSc: Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
1992-09--1996-07 BSc: Yantai University, Biochemistry and Microbiology
2014-01~2018-12 - Shanghai Institute of Biological Sciences/Shanghai Jiao Tong University School of Medicine - Researcher, Head of Tumor Drug Resistance Group, Doctoral Supervisor
2013-09~2013-12 - VA Medical Center, USA - Federal Researcher (PI, tenure track)
2013-09~2013-12 - University of Washington, USA - Researcher, Assistant Professor (both PI)
2006-09~2012-08 - Fred Hutchinson Cancer Research Center, USA - Postdoctoral Fellow, Staff Scientist
2005-03~2006-08 - University of British Columbia, Canada - Postdoctoral Fellow
1999-09~2000-09 - Institute of Genetics and Developmental Biology, Chinese Academy of Sciences - Assistant Researcher
Top Discoveries Award (2013): Research Institute
DODCDMRP Prostate Cancer Young Investigator Award (2012): First Prize, Department Level
DODCDMRP Prostate Cancer Postdoctoral Award (2008): Department Level
Patrick Lett Foundation Special Award (2004): Research Institute
Nova Scotia Health Research Foundation Award (2002): Provincial Level
Research
Tumor Microenvironment and Drug Resistance Cellular Senescence and Drug Targeting
Hyperbaric oxygen therapy for healthy aging: From mechanisms to therapeutics, Fu, Qiaoyu, Duan, Ran, Sun, Yu, Li, Qingfeng, 2022
KDM4 Orchestrates Epigenomic Remodeling of Senescent Cells and Potentiates the Senescence-Associated Secretory Phenotype, Boyi Zhang, Qilai Long, Shanshan Wu, Qixia Xu, Shuling Song, Liu Han, Min Qian, Xiaohui Ren, Hanxin Liu, Jing Jiang, Jianming Guo, Xiaoling Zhang, Xing Chang, Qiang Fu, Eric WF Lam, Judith Campisi, James L Kirkland, Yu Sun, 2021
Senescent stromal cells promote cancer resistance through SIRT1 loss-potentiated overproduction of small extracellular vesicles, Liu Han, Qilai Long, Shenjun Li, Qixia Xu, Boyi Zhang, Xuefeng Dou, Min Qian, Yannasittha Jiramongkol, Jianming Guo, Liu Cao, Y Eugene Chin, Eric WF Lam, Jing Jiang, Yu Sun, 2021
The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice, Xu, Qixia, Fu, Qiang, Li, Zi, Liu, Hanxin, Wang, Ying, Lin, Xu, He, Ruikun, Zhang, Xuguang, Ju, Zhenyu, Campisi, Judith, Kirkland, James L, Sun, Yu, 2021
Targeting Senescent Cells for a Healthier Aging: Challenges and Opportunities, Song, Shuling, Tchkonia, Tamara, Jiang, Jing, Kirkland, James L, Sun, Yu, 2020
Senescent Cells: Emerging Targets for Human Aging and Age-Related Diseases, Song, Shuling, Lam, Eric W F, Tchkonia, Tamara, Kirkland, James L, Sun, Yu, 2020
Extracellular vesicles in the tumor microenvironment: old stories, but new tales, Han, Liu, Lam, Eric W F, Sun, Yu, 2019
Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging, Munoz, Denise P, Yannone, Steven M, Daemen, Anneleen, Sun, Yu, VakarLopez, Funda, Kawahara, Misako, Freund, Adam M, Rodier, Francis, Wu, Jennifer D, Desprez, PierreYves, Raulet, David H, Nelson, Peter S, Veer, Laura J vant, Campis, Judith, Coppe, JeanPhilippe, 2019
Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression, Xu, Qixia, Long, Qilai, Zhu, Dexiang, Fu, Da, Zhang, Boyi, Han, Liu, Qian, Min, Guo, Jianming, Xu, Jianmin, Cao, Liu, Chin, Eugene, Coppe, JeanPhilippe, Lam, Eric WF, Campisi, Judith, Sun, Yu, 2019
Senescent cells: A new Achilles' heel to exploit for cancer medicine?, Zhang, Boyi, Lam, Eric W F, Sun, Yu, 2019
Targeting SPINK1 in the damaged tumour microenvironment alleviates therapeutic resistance, Fei Chen, Qilai Long, Da Fu, Dexiang Zhu, Yan Ji, Liu Han, Boyi Zhang, Qixia Xu, Bingjie Liu, Yan Li, Shanshan Wu, Chen Yang, Min Qian, Jianmin Xu, Suling Liu, Liu Cao, Y Eugene Chin, Eric WF Lam, JeanPhilippe Copp, Yu Sun, 2018
Cellular Senescence: The Sought or the Unwanted?, Sun, Yu, Coppe, JeanPhilippe, Lam, Eric W F, 2018
肿瘤微环境影响肿瘤多药耐药的研究进展, 潘雅娜, 王雪, 罗清, 2018
The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1, Boyi Zhang, Da Fu, Qixia Xu, Xianling Cong, Chunyan Wu, Xiaoming Zhong, Yushui Ma, Zhongwei Lv, Fei Chen, Liu Han, Min Qian, Y Eugene Chin, Eric W F Lam, Paul Chiao, Yu Sun, 2018
DNA Damage Induces a Secretory Program in the Quiescent TME that Fosters Adverse Cancer Phenotypes, GomezSarosi, Luis, Sun, Yu, Coleman, Ilsa, BianchiFrias, Daniella, Nelson, Peter S, 2017
Extracellular vesicles in the tumor microenvironment: Therapeutic resistance, clinical biomarkers, and targeting strategies, Han, L, Xu, J, Xu, Q, Zhang, B, Lam, E W F, Sun, Y, 2017
Revisiting ovarian cancer microenvironment: a friend or a foe?, Boyi Zhang, Fei Chen, Qixia Xu, Liu Han, Jiaqian Xu, Libin Gao, Xiaochen Sun, Yiwen Li, Yan Li, Min Qian, Yu Sun, 2017
SFRP2 augments WNT16B signaling to promote therapeutic resistance in the damaged tumor microenvironment, Sun, Y, Zhu, D, Chen, F, Qian, M, Wei, H, Chen, W, Xu, J, 2016
胞外囊泡与癌症, 韩柳, 孙宇, 2016
Tetrahedral Framework registration algorithm for the robot-assisted surgical navigation system, Zhu Jiebao, Sun Yu, Gao Peng, Ma Kailin, Hu Ying, Cao Yong, IEEE, 2016
Amphiregulin in Cancer: New Insights for Translational Medicine, Xu, Qixia, Chiao, Paul, Sun, Yu, 2016
基于区位文化视角的农民工劳动生产效率影响因素研究——以市政工程农民工为例, 孙宇, 2015
Tumor microenvironment and cancer therapy resistance, 孙宇, 2015
Translational Horizons in the Tumor Microenvironment: Harnessing Breakthroughs and Targeting Cures, Sun, Yu, 2015
Landscape and Targeting of the Angpt-Tie System in Current Anticancer Therapy, 孙宇, 2015
Regulation of the Cav1.2 cardiac channel by redox via modulation of CaM interaction with the channel, Sun, Yu, Xu, Jianjun, Minobe, Etsuko, Shimoara, Shoken, Hao, Liying, Kameyama, Masaki, 2015
New horizons in tumor microenvironment biology: challenges and opportunities, Chen, Fei, Zhuang, Xueqian, Lin, Liangyu, Yu, Pengfei, Wang, Ying, Shi, Yufang, Hu, Guohong, Sun, Yu, 2015