Yu Sun
sunyu@sibs.ac.cn
English, Chinese
Shanghai
University of Chinese Academy of Sciences
Medical School
  • 2000-10--2005-02 PhD: Dalhousie University, Life Sciences
  • 1996-09--1999-07 MSc: Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
  • 1992-09--1996-07 BSc: Yantai University, Biochemistry and Microbiology
  • 2014-01~2018-12 - Shanghai Institute of Biological Sciences/Shanghai Jiao Tong University School of Medicine - Researcher, Head of Tumor Drug Resistance Group, Doctoral Supervisor
  • 2013-09~2013-12 - VA Medical Center, USA - Federal Researcher (PI, tenure track)
  • 2013-09~2013-12 - University of Washington, USA - Researcher, Assistant Professor (both PI)
  • 2006-09~2012-08 - Fred Hutchinson Cancer Research Center, USA - Postdoctoral Fellow, Staff Scientist
  • 2005-03~2006-08 - University of British Columbia, Canada - Postdoctoral Fellow
  • 1999-09~2000-09 - Institute of Genetics and Developmental Biology, Chinese Academy of Sciences - Assistant Researcher
  • Top Discoveries Award (2013): Research Institute
  • DODCDMRP Prostate Cancer Young Investigator Award (2012): First Prize, Department Level
  • DODCDMRP Prostate Cancer Postdoctoral Award (2008): Department Level
  • Patrick Lett Foundation Special Award (2004): Research Institute
  • Nova Scotia Health Research Foundation Award (2002): Provincial Level
Tumor Microenvironment and Drug Resistance
Cellular Senescence and Drug Targeting
  • Hyperbaric oxygen therapy for healthy aging: From mechanisms to therapeutics, Fu, Qiaoyu, Duan, Ran, Sun, Yu, Li, Qingfeng, 2022
  • KDM4 Orchestrates Epigenomic Remodeling of Senescent Cells and Potentiates the Senescence-Associated Secretory Phenotype, Boyi Zhang, Qilai Long, Shanshan Wu, Qixia Xu, Shuling Song, Liu Han, Min Qian, Xiaohui Ren, Hanxin Liu, Jing Jiang, Jianming Guo, Xiaoling Zhang, Xing Chang, Qiang Fu, Eric WF Lam, Judith Campisi, James L Kirkland, Yu Sun, 2021
  • Senescent stromal cells promote cancer resistance through SIRT1 loss-potentiated overproduction of small extracellular vesicles, Liu Han, Qilai Long, Shenjun Li, Qixia Xu, Boyi Zhang, Xuefeng Dou, Min Qian, Yannasittha Jiramongkol, Jianming Guo, Liu Cao, Y Eugene Chin, Eric WF Lam, Jing Jiang, Yu Sun, 2021
  • The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice, Xu, Qixia, Fu, Qiang, Li, Zi, Liu, Hanxin, Wang, Ying, Lin, Xu, He, Ruikun, Zhang, Xuguang, Ju, Zhenyu, Campisi, Judith, Kirkland, James L, Sun, Yu, 2021
  • 铈锆固溶体CexZr1-xO2上H2S的选择性催化氧化性能, 孙宇, 张鑫, 张凤莲, 蒋国霞, 魏征, 郝郑平, 2020
  • Targeting Senescent Cells for a Healthier Aging: Challenges and Opportunities, Song, Shuling, Tchkonia, Tamara, Jiang, Jing, Kirkland, James L, Sun, Yu, 2020
  • Senescent Cells: Emerging Targets for Human Aging and Age-Related Diseases, Song, Shuling, Lam, Eric W F, Tchkonia, Tamara, Kirkland, James L, Sun, Yu, 2020
  • Extracellular vesicles in the tumor microenvironment: old stories, but new tales, Han, Liu, Lam, Eric W F, Sun, Yu, 2019
  • Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging, Munoz, Denise P, Yannone, Steven M, Daemen, Anneleen, Sun, Yu, VakarLopez, Funda, Kawahara, Misako, Freund, Adam M, Rodier, Francis, Wu, Jennifer D, Desprez, PierreYves, Raulet, David H, Nelson, Peter S, Veer, Laura J vant, Campis, Judith, Coppe, JeanPhilippe, 2019
  • Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression, Xu, Qixia, Long, Qilai, Zhu, Dexiang, Fu, Da, Zhang, Boyi, Han, Liu, Qian, Min, Guo, Jianming, Xu, Jianmin, Cao, Liu, Chin, Eugene, Coppe, JeanPhilippe, Lam, Eric WF, Campisi, Judith, Sun, Yu, 2019
  • Senescent cells: A new Achilles' heel to exploit for cancer medicine?, Zhang, Boyi, Lam, Eric W F, Sun, Yu, 2019
  • 黔北习水地区五峰-龙马溪组页岩地球化学与热演化特征及页岩气前景展望, 史树勇, 孙宇, 郭慧娟, 邓瑞, 陈承声, 王云鹏, 2019
  • Targeting SPINK1 in the damaged tumour microenvironment alleviates therapeutic resistance, Fei Chen, Qilai Long, Da Fu, Dexiang Zhu, Yan Ji, Liu Han, Boyi Zhang, Qixia Xu, Bingjie Liu, Yan Li, Shanshan Wu, Chen Yang, Min Qian, Jianmin Xu, Suling Liu, Liu Cao, Y Eugene Chin, Eric WF Lam, JeanPhilippe Copp, Yu Sun, 2018
  • Cellular Senescence: The Sought or the Unwanted?, Sun, Yu, Coppe, JeanPhilippe, Lam, Eric W F, 2018
  • 肿瘤微环境影响肿瘤多药耐药的研究进展, 潘雅娜, 王雪, 罗清, 2018
  • The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1, Boyi Zhang, Da Fu, Qixia Xu, Xianling Cong, Chunyan Wu, Xiaoming Zhong, Yushui Ma, Zhongwei Lv, Fei Chen, Liu Han, Min Qian, Y Eugene Chin, Eric W F Lam, Paul Chiao, Yu Sun, 2018
  • DNA Damage Induces a Secretory Program in the Quiescent TME that Fosters Adverse Cancer Phenotypes, GomezSarosi, Luis, Sun, Yu, Coleman, Ilsa, BianchiFrias, Daniella, Nelson, Peter S, 2017
  • Extracellular vesicles in the tumor microenvironment: Therapeutic resistance, clinical biomarkers, and targeting strategies, Han, L, Xu, J, Xu, Q, Zhang, B, Lam, E W F, Sun, Y, 2017
  • Revisiting ovarian cancer microenvironment: a friend or a foe?, Boyi Zhang, Fei Chen, Qixia Xu, Liu Han, Jiaqian Xu, Libin Gao, Xiaochen Sun, Yiwen Li, Yan Li, Min Qian, Yu Sun, 2017
  • SFRP2 augments WNT16B signaling to promote therapeutic resistance in the damaged tumor microenvironment, Sun, Y, Zhu, D, Chen, F, Qian, M, Wei, H, Chen, W, Xu, J, 2016
  • 胞外囊泡与癌症, 韩柳, 孙宇, 2016
  • Tetrahedral Framework registration algorithm for the robot-assisted surgical navigation system, Zhu Jiebao, Sun Yu, Gao Peng, Ma Kailin, Hu Ying, Cao Yong, IEEE, 2016
  • Amphiregulin in Cancer: New Insights for Translational Medicine, Xu, Qixia, Chiao, Paul, Sun, Yu, 2016
  • 基于区位文化视角的农民工劳动生产效率影响因素研究——以市政工程农民工为例, 孙宇, 2015
  • Tumor microenvironment and cancer therapy resistance, 孙宇, 2015
  • Translational Horizons in the Tumor Microenvironment: Harnessing Breakthroughs and Targeting Cures, Sun, Yu, 2015
  • Landscape and Targeting of the Angpt-Tie System in Current Anticancer Therapy, 孙宇, 2015
  • Regulation of the Cav1.2 cardiac channel by redox via modulation of CaM interaction with the channel, Sun, Yu, Xu, Jianjun, Minobe, Etsuko, Shimoara, Shoken, Hao, Liying, Kameyama, Masaki, 2015
  • New horizons in tumor microenvironment biology: challenges and opportunities, Chen, Fei, Zhuang, Xueqian, Lin, Liangyu, Yu, Pengfei, Wang, Ying, Shi, Yufang, Hu, Guohong, Sun, Yu, 2015
Tumor Microenvironment Drug Resistance Cellular Senescence Drug Targeting Cancer Therapeutics Biochemistry Microbiology Oncology Research

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