2022-10 - Present - Institute of Microbiology, Chinese Academy of Sciences - Researcher
2021-11 - Present - Institute of Microbiology, Chinese Academy of Sciences - Project Researcher
2017-09 - Present - Institute of Microbiology, Chinese Academy of Sciences - Associate Researcher
2012-07 - Present - Institute of Microbiology, Chinese Academy of Sciences - Assistant Researcher
2010-04 - Present - Nevada Cancer Institute, USA - Visiting Scholar
Research
Pathogen Infection and Host Immunity
A mycobacterial effector promotes ferroptosis-dependent pathogenicity and dissemination, Corresponding Author, 2023
TRIM27 maintains gut homeostasis by promoting intestinal stem cell self-renewal, First Author, 2023
Science and Technology Facilitates Tuberculosis Prevention and Control: Current Situation, Progress and Countermeasures, Third Author, 2022
A bacterial phospholipid phosphatase inhibits host pyroptosis by hijacking ubiquitin, Corresponding Author, 2022
M. tuberculosis PknG manipulates host autophagy flux to promote pathogen intracellular survival, Corresponding Author, 2022
Mycobacterium tuberculosis protein kinase G acts as an unusual ubiquitinating enzyme to impair host immunity, First Author, 2021
Ubiquitination-Dependent Regulation of Small GTPases in Membrane Trafficking: From Cell Biology to Human Diseases, Second Author, 2021
HDAC6 contributes to human resistance against Mycobacterium tuberculosis infection via mediating innate immune responses, Fourth Author, 2021
A Novel Aquaporin Subfamily Imports Oxygen and Contributes to Pneumococcal Virulence by Controlling the Production and Release of Virulence Factors, Third Author, 2021
Research progress of regulatory roles and mechanisms of autophagy in anti-infection immunity, Second Author, 2020
Simulated microgravity suppresses MAPK pathway-mediated innate immune response to bacterial infection and induces gut microbiota dysbiosis, First Author, 2020
Lung gene expression signatures suggest pathogenic links and molecular markers for pulmonary tuberculosis, adenocarcinoma and sarcoidosis, Eighth Author, 2020
A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy, Ninth Author, 2019
Mycobacterium tuberculosis Mce2E suppresses the macrophage innate immune response and promotes epithelial cell proliferation, Second Author, 2019
Mycobacterium tuberculosis Mce3C promotes mycobacteria entry into macrophages through activation of beta 2 integrin-mediated signalling pathway, Fourth Author, 2018
Klebsiella pneumoniae NdpA suppresses ERK pathway-mediated host early inflammatory responses and is degraded through the ubiquitin-proteasome pathway, Second Author, 2017
The mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferation, First Author, 2017
M. tuberculosis Mce3C promotes mycobacterial mammalian cell entrance and enhances mycobactrial intracellular survival, Fourth Author, 2016
The ubiquitin ligase TRIM27 functions as a host restriction factor antagonized by Mycobacterium tuberculosis PtpA during mycobacterial infection, First Author, 2016
Mycobacterium tuberculosis suppresses innate immunity by coopting the host ubiquitin system, First Author, 2015
