Areas of Focus
- Pathogen Infection and Host Immunity
Work Experience
- 2022-10 - Present - Institute of Microbiology, Chinese Academy of Sciences - Researcher
- 2021-11 - Present - Institute of Microbiology, Chinese Academy of Sciences - Project Researcher
- 2017-09 - Present - Institute of Microbiology, Chinese Academy of Sciences - Associate Researcher
- 2012-07 - Present - Institute of Microbiology, Chinese Academy of Sciences - Assistant Researcher
- 2010-04 - Present - Nevada Cancer Institute, USA - Visiting Scholar
Academic Background & Achievements
- 2007-09 - Ph.D.: Peking University
- 2003-09 - Bachelor's: Hebei University
Publications
- A mycobacterial effector promotes ferroptosis-dependent pathogenicity and dissemination, Corresponding Author, 2023
- TRIM27 maintains gut homeostasis by promoting intestinal stem cell self-renewal, First Author, 2023
- Science and Technology Facilitates Tuberculosis Prevention and Control: Current Situation, Progress and Countermeasures, Third Author, 2022
- A bacterial phospholipid phosphatase inhibits host pyroptosis by hijacking ubiquitin, Corresponding Author, 2022
- M. tuberculosis PknG manipulates host autophagy flux to promote pathogen intracellular survival, Corresponding Author, 2022
- Mycobacterium tuberculosis protein kinase G acts as an unusual ubiquitinating enzyme to impair host immunity, First Author, 2021
- Ubiquitination-Dependent Regulation of Small GTPases in Membrane Trafficking: From Cell Biology to Human Diseases, Second Author, 2021
- HDAC6 contributes to human resistance against Mycobacterium tuberculosis infection via mediating innate immune responses, Fourth Author, 2021
- A Novel Aquaporin Subfamily Imports Oxygen and Contributes to Pneumococcal Virulence by Controlling the Production and Release of Virulence Factors, Third Author, 2021
- Research progress of regulatory roles and mechanisms of autophagy in anti-infection immunity, Second Author, 2020
- Simulated microgravity suppresses MAPK pathway-mediated innate immune response to bacterial infection and induces gut microbiota dysbiosis, First Author, 2020
- Lung gene expression signatures suggest pathogenic links and molecular markers for pulmonary tuberculosis, adenocarcinoma and sarcoidosis, Eighth Author, 2020
- A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy, Ninth Author, 2019
- Mycobacterium tuberculosis Mce2E suppresses the macrophage innate immune response and promotes epithelial cell proliferation, Second Author, 2019
- Mycobacterium tuberculosis Mce3C promotes mycobacteria entry into macrophages through activation of beta 2 integrin-mediated signalling pathway, Fourth Author, 2018
- Klebsiella pneumoniae NdpA suppresses ERK pathway-mediated host early inflammatory responses and is degraded through the ubiquitin-proteasome pathway, Second Author, 2017
- The mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferation, First Author, 2017
- M. tuberculosis Mce3C promotes mycobacterial mammalian cell entrance and enhances mycobactrial intracellular survival, Fourth Author, 2016
- The ubiquitin ligase TRIM27 functions as a host restriction factor antagonized by Mycobacterium tuberculosis PtpA during mycobacterial infection, First Author, 2016
- Mycobacterium tuberculosis suppresses innate immunity by coopting the host ubiquitin system, First Author, 2015
- Mycobacterium tuberculosis Mce3E Suppresses Host Innate Immune Responses by Targeting ERK1/2 Signaling, Fifth Author, 2015
- Insights into battles between Mycobacterium tuberculosis and macrophages, Second Author, 2014
- Insights into battles between Mycobacterium tuberculosis and macrophages, Second Author, 2014
- Pluripotent Stem Cell Protein Sox2 Confers Sensitivity to LSD1 Inhibition in Cancer Cells, Third Author, 2013
- Dissecting the phenotypes of Plk1 inhibition in cancer cells using novel kinase inhibitory chemical CBB2001, Sixth Author, 2012
- Novel Histone Demethylase LSD1 Inhibitors Selectively Target Cancer Cells with Pluripotent Stem Cell Properties, First Author, 2011
