Areas of Focus
- 病原感染与宿主免疫
Work Experience
- 2022-10 - 现在 - 中国科学院微生物研究所 - 研究员
- 2021-11 - 现在 - 中国科学院微生物研究所 - 项目研究员
- 2017-09 - 现在 - 中国科学院微生物研究所 - 副研究员
- 2012-07 - 现在 - 中国科学院微生物研究所 - 助理研究员
- 2010-04 - 现在 - 美国内华达肿瘤研究所 - 访问学者
Academic Background & Achievements
- 2007-09 - 博士: 北京大学
- 2003-09 - 学士: 河北大学
Publications
- A mycobacterial effector promotes ferroptosis-dependent pathogenicity and dissemination, 通讯作者, 2023
- TRIM27 maintains gut homeostasis by promoting intestinal stem cell self-renewal, 第 1 作者, 2023
- 科技助力结核病防控：现状、进展与对策, 第 3 作者, 2022
- A bacterial phospholipid phosphatase inhibits host pyroptosis by hijacking ubiquitin, 通讯作者, 2022
- M. tuberculosis PknG manipulates host autophagy flux to promote pathogen intracellular survival, 通讯作者, 2022
- Mycobacterium tuberculosis protein kinase G acts as an unusual ubiquitinating enzyme to impair host immunity, 第 1 作者, 2021
- Ubiquitination-Dependent Regulation of Small GTPases in Membrane Trafficking: From Cell Biology to Human Diseases, 第 2 作者, 2021
- HDAC6 contributes to human resistance against Mycobacterium tuberculosis infection via mediating innate immune responses, 第 4 作者, 2021
- A Novel Aquaporin Subfamily Imports Oxygen and Contributes to Pneumococcal Virulence by Controlling the Production and Release of Virulence Factors, 第 3 作者, 2021
- 自噬在抗感染免疫中的作用机制研究进展, 第 2 作者, 2020
- Simulated microgravity suppresses MAPK pathway-mediated innate immune response to bacterial infection and induces gut microbiota dysbiosis, 第 1 作者, 2020
- Lung gene expression signatures suggest pathogenic links and molecular markers for pulmonary tuberculosis, adenocarcinoma and sarcoidosis, 第 8 作者, 2020
- A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy, 第 9 作者, 2019
- Mycobacterium tuberculosis Mce2E suppresses the macrophage innate immune response and promotes epithelial cell proliferation, 第 2 作者, 2019
- Mycobacterium tuberculosis Mce3C promotes mycobacteria entry into macrophages through activation of beta 2 integrin-mediated signalling pathway, 第 4 作者, 2018
- Klebsiella pneumoniae NdpA suppresses ERK pathway-mediated host early inflammatory responses and is degraded through the ubiquitin-proteasome pathway, 第 2 作者, 2017
- The mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferation, 第 1 作者, 2017
- M. tuberculosis Mce3C promotes mycobacterial mammalian cell entrance and enhances mycobactrial intracellular survival, 第 4 作者, 2016
- The ubiquitin ligase TRIM27 functions as a host restriction factor antagonized by Mycobacterium tuberculosis PtpA during mycobacterial infection, 第 1 作者, 2016
- Mycobacterium tuberculosis suppresses innate immunity by coopting the host ubiquitin system, 第 1 作者, 2015
- Mycobacterium tuberculosis Mce3E Suppresses Host Innate Immune Responses by Targeting ERK1/2 Signaling, 第 5 作者, 2015
- Insights into battles between Mycobacterium tuberculosis and macrophages, 第 2 作者, 2014
- Insights into battles between Mycobacterium tuberculosis and macrophages, 第 2 作者, 2014
- Pluripotent Stem Cell Protein Sox2 Confers Sensitivity to LSD1 Inhibition in Cancer Cells, 第 3 作者, 2013
- Dissecting the phenotypes of Plk1 inhibition in cancer cells using novel kinase inhibitory chemical CBB2001, 第 6 作者, 2012
- Novel Histone Demethylase LSD1 Inhibitors Selectively Target Cancer Cells with Pluripotent Stem Cell Properties, 第 1 作者, 2011
