Professor | Wang Luoyi | Asia Growth Partners

Name	Wang Luoyi
Contact Information	wangluoyi@im.ac.cn
Language ability	Chinese, English
Province	Beijing

Name

Wang Luoyi

Contact Information

wangluoyi@im.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2008-09 to 2013-07 PhD in Science: Shanghai Institute of Materia Medica, Chinese Academy of Sciences 2004-09 to 2008-06 Bachelor of Medicine: Southern Medical University
Work Experience	2014-11 to 2020-10 - University of Bristol - Postdoctoral Researcher 2014-03 to 2014-10 - Ohio State University - Postdoctoral Researcher 2013-09 to 2014-03 - Utah State University - Postdoctoral Researcher 2008-09 to 2013-07 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - PhD in Science 2004-09 to 2008-06 - Southern Medical University - Bachelor of Medicine

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2008-09 to 2013-07 PhD in Science: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
2004-09 to 2008-06 Bachelor of Medicine: Southern Medical University

Work Experience

2014-11 to 2020-10 - University of Bristol - Postdoctoral Researcher
2014-03 to 2014-10 - Ohio State University - Postdoctoral Researcher
2013-09 to 2014-03 - Utah State University - Postdoctoral Researcher
2008-09 to 2013-07 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - PhD in Science
2004-09 to 2008-06 - Southern Medical University - Bachelor of Medicine

Areas of Focus	Microbiology and Biochemical Pharmacy
Publications	Combining total synthesis and genetic engineering to probe dihydropyran formation in ambruticin biosynthesis, 11th Author, 2024 Structure and Function of the β-Hydroxylation Bimodule of the Mupirocin Polyketide Synthase, 5th Author, 2023 A hybrid system for the overproduction of complex ergot alkaloid chanoclavine, 11th Author, 2022 Synthetic and biosynthetic methods for selective cyclisations of 4,5-epoxy alcohols to tetrahydropyrans, 2nd Author, 2022 Ambruticins: tetrahydropyran ring formation and total synthesis, 2nd Author, 2021 A Priming Cassette Generates Hydroxylated Acyl Starter Units in Mupirocin and Thiomarinol Biosynthesis, 6th Author, 2020 Mixing and matching genes of marine and terrestrial origin in the biosynthesis of the mupirocin antibiotics, 1st Author, 2020 A Rieske oxygenase/epoxide hydrolase-catalysed reaction cascade creates oxygen heterocycles in mupirocin biosynthesis, 1st Author, 2018 Absolute Configuration of Periplosides C and F and Isolation of Minor Spiro-orthoester Group-Containing Pregnane-type Steroidal Glycosides from Periploca sepium and Their T-Lymphocyte Proliferation Inhibitory Activities, 1st Author, 2017 Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics, 2nd Author, 2017 Structural revision of periplocosides and periperoxides, natural immunosuppressive agents from the genus Periploca (vol 72, pg 2230, 2011), 1st Author, 2013 (M)- and (P)-Bicelaphanol A, Dimeric Trinorditerpenes with Promising Neuroprotective Activity from Celastrus orbiculatus, 1st Author, 2013 Appetite suppressing pregnane glycosides from the roots of Cynanchum auriculatum, 4th Author, 2013 New iridoid glycoside and triterpenoid glycoside from Premna fulva, 2nd Author, 2013 Ac-cel, a Novel Antioxidant, Protects Against Hydrogen Peroxide-induced Injury in PC12 Cells via Attenuation of Mitochondrial Dysfunction, 5th Author, 2013 Promising effects on ameliorating mitochondrial function and enhancing Akt signaling in SH-SY5Y cells by (M)-bicelaphanol A, a novel dimeric podocarpane type trinorditerpene isolated from Celastrus orbiculatus, 2nd Author, 2013 Terpenoids from root bark of Celastrus orbiculatus, 3rd Author, 2012 Structural revision of periplocosides and periperoxides, natural immunosuppressive agents from the genus Periploca, 1st Author, 2011 Two new glycosides from Breynia vitis-idaea, 3rd Author, 2010

Areas of Focus

Microbiology and Biochemical Pharmacy

Publications

Combining total synthesis and genetic engineering to probe dihydropyran formation in ambruticin biosynthesis, 11th Author, 2024
Structure and Function of the β-Hydroxylation Bimodule of the Mupirocin Polyketide Synthase, 5th Author, 2023
A hybrid system for the overproduction of complex ergot alkaloid chanoclavine, 11th Author, 2022
Synthetic and biosynthetic methods for selective cyclisations of 4,5-epoxy alcohols to tetrahydropyrans, 2nd Author, 2022
Ambruticins: tetrahydropyran ring formation and total synthesis, 2nd Author, 2021
A Priming Cassette Generates Hydroxylated Acyl Starter Units in Mupirocin and Thiomarinol Biosynthesis, 6th Author, 2020
Mixing and matching genes of marine and terrestrial origin in the biosynthesis of the mupirocin antibiotics, 1st Author, 2020
A Rieske oxygenase/epoxide hydrolase-catalysed reaction cascade creates oxygen heterocycles in mupirocin biosynthesis, 1st Author, 2018
Absolute Configuration of Periplosides C and F and Isolation of Minor Spiro-orthoester Group-Containing Pregnane-type Steroidal Glycosides from Periploca sepium and Their T-Lymphocyte Proliferation Inhibitory Activities, 1st Author, 2017
Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics, 2nd Author, 2017
Structural revision of periplocosides and periperoxides, natural immunosuppressive agents from the genus Periploca (vol 72, pg 2230, 2011), 1st Author, 2013
(M)- and (P)-Bicelaphanol A, Dimeric Trinorditerpenes with Promising Neuroprotective Activity from Celastrus orbiculatus, 1st Author, 2013
Appetite suppressing pregnane glycosides from the roots of Cynanchum auriculatum, 4th Author, 2013
New iridoid glycoside and triterpenoid glycoside from Premna fulva, 2nd Author, 2013
Ac-cel, a Novel Antioxidant, Protects Against Hydrogen Peroxide-induced Injury in PC12 Cells via Attenuation of Mitochondrial Dysfunction, 5th Author, 2013
Promising effects on ameliorating mitochondrial function and enhancing Akt signaling in SH-SY5Y cells by (M)-bicelaphanol A, a novel dimeric podocarpane type trinorditerpene isolated from Celastrus orbiculatus, 2nd Author, 2013
Terpenoids from root bark of Celastrus orbiculatus, 3rd Author, 2012
Structural revision of periplocosides and periperoxides, natural immunosuppressive agents from the genus Periploca, 1st Author, 2011
Two new glycosides from Breynia vitis-idaea, 3rd Author, 2010

Microbiology Biochemical Pharmacy Genetic Engineering Biosynthesis Antibiotics Enzymology Natural Products Immunosuppressive Agents Drug Discovery Biocatalysis

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