Professor | 王罗医 | 数字化转型顾问

Name	王罗医
Contact Information	wangluoyi@im.ac.cn
Language ability	中文, 英语
Province	北京

Name

王罗医

Contact Information

wangluoyi@im.ac.cn

Language ability

中文, 英语

Province

北京

University/Lab Affiliation and Title	中国科学院大学
Faculty	Medical School
Academic Background & Achievements	2008-09到2013-07 理学博士: 中国科学院上海药物研究所 2004-09到2008-06 医学学士: 南方医科大学
Work Experience	2014-11到2020-10 - 布里斯托尔大学 - 博士后 2014-03到2014-10 - 俄亥俄州立大学 - 博士后 2013-09到2014-03 - 犹他州立大学 - 博士后 2008-09到2013-07 - 中国科学院上海药物研究所 - 理学博士 2004-09到2008-06 - 南方医科大学 - 医学学士

University/Lab Affiliation and Title

中国科学院大学

Faculty

Medical School

Academic Background & Achievements

2008-09到2013-07 理学博士: 中国科学院上海药物研究所
2004-09到2008-06 医学学士: 南方医科大学

Work Experience

2014-11到2020-10 - 布里斯托尔大学 - 博士后
2014-03到2014-10 - 俄亥俄州立大学 - 博士后
2013-09到2014-03 - 犹他州立大学 - 博士后
2008-09到2013-07 - 中国科学院上海药物研究所 - 理学博士
2004-09到2008-06 - 南方医科大学 - 医学学士

Areas of Focus	微生物与生化药学
Publications	Combining total synthesis and genetic engineering to probe dihydropyran formation in ambruticin biosynthesis, 第11作者, 2024 Structure and Function of the β-Hydroxylation Bimodule of the Mupirocin Polyketide Synthase, 第5作者, 2023 A hybrid system for the overproduction of complex ergot alkaloid chanoclavine, 第11作者, 2022 Synthetic and biosynthetic methods for selective cyclisations of 4,5-epoxy alcohols to tetrahydropyrans, 第2作者, 2022 Ambruticins: tetrahydropyran ring formation and total synthesis, 第2作者, 2021 A Priming Cassette Generates Hydroxylated Acyl Starter Units in Mupirocin and Thiomarinol Biosynthesis, 第6作者, 2020 Mixing and matching genes of marine and terrestrial origin in the biosynthesis of the mupirocin antibiotics, 第1作者, 2020 A Rieske oxygenase/epoxide hydrolase-catalysed reaction cascade creates oxygen heterocycles in mupirocin biosynthesis, 第1作者, 2018 Absolute Configuration of Periplosides C and F and Isolation of Minor Spiro-orthoester Group-Containing Pregnane-type Steroidal Glycosides from Periploca sepium and Their T-Lymphocyte Proliferation Inhibitory Activities, 第1作者, 2017 Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics, 第2作者, 2017 Structural revision of periplocosides and periperoxides, natural immunosuppressive agents from the genus Periploca (vol 72, pg 2230, 2011), 第1作者, 2013 (M)- and (P)-Bicelaphanol A, Dimeric Trinorditerpenes with Promising Neuroprotective Activity from Celastrus orbiculatus, 第1作者, 2013 Appetite suppressing pregnane glycosides from the roots of Cynanchum auriculatum, 第4作者, 2013 New iridoid glycoside and triterpenoid glycoside from Premna fulva, 第2作者, 2013 Ac-cel, a Novel Antioxidant, Protects Against Hydrogen Peroxide-induced Injury in PC12 Cells via Attenuation of Mitochondrial Dysfunction, 第5作者, 2013 Promising effects on ameliorating mitochondrial function and enhancing Akt signaling in SH-SY5Y cells by (M)-bicelaphanol A, a novel dimeric podocarpane type trinorditerpene isolated from Celastrus orbiculatus, 第2作者, 2013 Terpenoids from root bark of Celastrus orbiculatus, 第3作者, 2012 Structural revision of periplocosides and periperoxides, natural immunosuppressive agents from the genus Periploca, 第1作者, 2011 Two new glycosides from Breynia vitis-idaea, 第3作者, 2010

Areas of Focus

微生物与生化药学

Publications

Combining total synthesis and genetic engineering to probe dihydropyran formation in ambruticin biosynthesis, 第11作者, 2024
Structure and Function of the β-Hydroxylation Bimodule of the Mupirocin Polyketide Synthase, 第5作者, 2023
A hybrid system for the overproduction of complex ergot alkaloid chanoclavine, 第11作者, 2022
Synthetic and biosynthetic methods for selective cyclisations of 4,5-epoxy alcohols to tetrahydropyrans, 第2作者, 2022
Ambruticins: tetrahydropyran ring formation and total synthesis, 第2作者, 2021
A Priming Cassette Generates Hydroxylated Acyl Starter Units in Mupirocin and Thiomarinol Biosynthesis, 第6作者, 2020
Mixing and matching genes of marine and terrestrial origin in the biosynthesis of the mupirocin antibiotics, 第1作者, 2020
A Rieske oxygenase/epoxide hydrolase-catalysed reaction cascade creates oxygen heterocycles in mupirocin biosynthesis, 第1作者, 2018
Absolute Configuration of Periplosides C and F and Isolation of Minor Spiro-orthoester Group-Containing Pregnane-type Steroidal Glycosides from Periploca sepium and Their T-Lymphocyte Proliferation Inhibitory Activities, 第1作者, 2017
Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics, 第2作者, 2017
Structural revision of periplocosides and periperoxides, natural immunosuppressive agents from the genus Periploca (vol 72, pg 2230, 2011), 第1作者, 2013
(M)- and (P)-Bicelaphanol A, Dimeric Trinorditerpenes with Promising Neuroprotective Activity from Celastrus orbiculatus, 第1作者, 2013
Appetite suppressing pregnane glycosides from the roots of Cynanchum auriculatum, 第4作者, 2013
New iridoid glycoside and triterpenoid glycoside from Premna fulva, 第2作者, 2013
Ac-cel, a Novel Antioxidant, Protects Against Hydrogen Peroxide-induced Injury in PC12 Cells via Attenuation of Mitochondrial Dysfunction, 第5作者, 2013
Promising effects on ameliorating mitochondrial function and enhancing Akt signaling in SH-SY5Y cells by (M)-bicelaphanol A, a novel dimeric podocarpane type trinorditerpene isolated from Celastrus orbiculatus, 第2作者, 2013
Terpenoids from root bark of Celastrus orbiculatus, 第3作者, 2012
Structural revision of periplocosides and periperoxides, natural immunosuppressive agents from the genus Periploca, 第1作者, 2011
Two new glycosides from Breynia vitis-idaea, 第3作者, 2010

微生物学生化药学基因工程生物合成抗生素酶学天然产物免疫抑制剂药物发现生物催化

陈义华 - 中国科学院大学

邓子新 - 武汉大学

虞沂 - 武汉大学

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