Professor | Xu Ling | Asia Growth Partners

Name	Xu Ling
Contact Information	xuling0502@mail.kiz.ac.cn
Language ability	Chinese, English
Province	Yunnan

Name

Xu Ling

Contact Information

xuling0502@mail.kiz.ac.cn

Language ability

Chinese, English

Province

Yunnan

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2009-09--2014-07 Bachelor's Degree: Huazhong Agricultural University 2009-09--2015-01 Doctorate: University of Chinese Academy of Sciences
Work Experience	2018-01~Present - Kunming Institute of Zoology, Chinese Academy of Sciences - Associate Researcher 2015-01~2017-12 - Kunming Institute of Zoology, Chinese Academy of Sciences - Assistant Researcher
Awards	Chinese Society for Immunology 7th Young Scholar Award (2017): First Prize

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2009-09--2014-07 Bachelor's Degree: Huazhong Agricultural University
2009-09--2015-01 Doctorate: University of Chinese Academy of Sciences

Work Experience

2018-01~Present - Kunming Institute of Zoology, Chinese Academy of Sciences - Associate Researcher
2015-01~2017-12 - Kunming Institute of Zoology, Chinese Academy of Sciences - Assistant Researcher

Awards

Chinese Society for Immunology 7th Young Scholar Award (2017): First Prize

Areas of Focus	Infection and Immunity
Publications	A combination vaccine against SARS-CoV-2 and H1N1 influenza based on receptor binding domain trimerized by six-helix bundle fusion core, Third Author, 2022 Specific inhibition of the NLRP3 inflammasome suppresses immune overactivation and alleviates COVID-19 like pathology in mice, Fourth Author, 2022 Tupaia guanylate-binding protein 1 interacts with vesicular stomatitis virus phosphoprotein and represses primary transcription of the viral genome, Third Author, 2021 Lower respiratory tract samples are reliable for severe acute respiratory syndrome coronavirus 2 nucleic acid diagnosis and animal model study, Tenth Author, 2021 Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models, Ninth Author, 2021 COVID-19-like symptoms observed in Chinese tree shrews infected with SARS-CoV-2, First Author, 2020 Tupaia OASL1 Promotes Cellular Antiviral Immune Responses by Recruiting MDA5 to MAVS, Third Author, 2020 An Alternative Splicing of Tupaia STING Modulated Anti-RNA Virus Responses by Targeting MDA5-LGP2 and IRF3, First Author, 2020 Tupaia MAVS is a dual target during HCV infection for innate immune evasion and viral replication via NF-��B, First Author, 2020 Tupaia MAVS Is a Dual Target during Hepatitis C Virus Infection for Innate Immune Evasion and Viral Replication via NF-kappa B, First Author, 2020 Extracellular Vesicle-Mediated Delivery of Circular RNA SCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models, Ninth Author, 2020 The 3��UTR of human MAVS mRNA contains multiple regulatory elements for the control of protein expression and subcellular localization, First Author, 2019 Establishment and characterization of an immortalized renal cell line of the Chinese tree shrew (Tupaia belangeri chinesis), Fourth Author, 2019 Evolutionary selection on MDA5 and LGP2 in the chicken preserves antiviral competence in the absence of RIG-I, First Author, 2019 Molecular identification and antiviral function of the guanylate-binding protein (GBP) genes in the Chinese tree shrew (Tupaia belangeri chinesis), Eleventh Author, 2019 The 3 ' UTR of human MAVS mRNA contains multiple regulatory elements for the control of protein expression and subcellular localization, First Author, 2019 Native musk and synthetic musk ketone strongly induced the growth repression and the apoptosis of cancer cells, First Author, 2016 Loss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew., First Author, 2016 Characterization of a MAVS ortholog from the Chinese tree shrew (Tupaia belangeri chinensis), First Author, 2015 Analysis of the complete mitochondrial genome and characterization of diverse NUMTs of Macaca leonina, Third Author, 2015 IDH1 p.R132 mutations may not be actively involved in the carcinogenesis of hepatocellular carcinoma, Third Author, 2014 树鼩进化分类地位的分子证据, First Author, 2013 GENETIC ENGINEERING NEURAL STEM CELL MODIFIED BY LENTIVIRUS FOR REPAIR OF SPINAL CORD INJURY IN RATS, Sixth Author, 2006

Areas of Focus

Infection and Immunity

Publications

A combination vaccine against SARS-CoV-2 and H1N1 influenza based on receptor binding domain trimerized by six-helix bundle fusion core, Third Author, 2022
Specific inhibition of the NLRP3 inflammasome suppresses immune overactivation and alleviates COVID-19 like pathology in mice, Fourth Author, 2022
Tupaia guanylate-binding protein 1 interacts with vesicular stomatitis virus phosphoprotein and represses primary transcription of the viral genome, Third Author, 2021
Lower respiratory tract samples are reliable for severe acute respiratory syndrome coronavirus 2 nucleic acid diagnosis and animal model study, Tenth Author, 2021
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models, Ninth Author, 2021
COVID-19-like symptoms observed in Chinese tree shrews infected with SARS-CoV-2, First Author, 2020
Tupaia OASL1 Promotes Cellular Antiviral Immune Responses by Recruiting MDA5 to MAVS, Third Author, 2020
An Alternative Splicing of Tupaia STING Modulated Anti-RNA Virus Responses by Targeting MDA5-LGP2 and IRF3, First Author, 2020
Tupaia MAVS is a dual target during HCV infection for innate immune evasion and viral replication via NF-��B, First Author, 2020
Tupaia MAVS Is a Dual Target during Hepatitis C Virus Infection for Innate Immune Evasion and Viral Replication via NF-kappa B, First Author, 2020
Extracellular Vesicle-Mediated Delivery of Circular RNA SCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models, Ninth Author, 2020
The 3��UTR of human MAVS mRNA contains multiple regulatory elements for the control of protein expression and subcellular localization, First Author, 2019
Establishment and characterization of an immortalized renal cell line of the Chinese tree shrew (Tupaia belangeri chinesis), Fourth Author, 2019
Evolutionary selection on MDA5 and LGP2 in the chicken preserves antiviral competence in the absence of RIG-I, First Author, 2019
Molecular identification and antiviral function of the guanylate-binding protein (GBP) genes in the Chinese tree shrew (Tupaia belangeri chinesis), Eleventh Author, 2019
The 3 ' UTR of human MAVS mRNA contains multiple regulatory elements for the control of protein expression and subcellular localization, First Author, 2019
Native musk and synthetic musk ketone strongly induced the growth repression and the apoptosis of cancer cells, First Author, 2016
Loss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew., First Author, 2016
Characterization of a MAVS ortholog from the Chinese tree shrew (Tupaia belangeri chinensis), First Author, 2015
Analysis of the complete mitochondrial genome and characterization of diverse NUMTs of Macaca leonina, Third Author, 2015
IDH1 p.R132 mutations may not be actively involved in the carcinogenesis of hepatocellular carcinoma, Third Author, 2014
树鼩进化分类地位的分子证据, First Author, 2013
GENETIC ENGINEERING NEURAL STEM CELL MODIFIED BY LENTIVIRUS FOR REPAIR OF SPINAL CORD INJURY IN RATS, Sixth Author, 2006

Infection Immunity Sars-Cov-2 H1N1 Nlrp3 Inflammasome Covid-19 Tupaia Mavs Hcv Nf-Kappa B

Yingying Zhang - Wuhan University

Lifeng Fu - University of Chinese Academy of Sciences

Xiaoli Xiong - University of Chinese Academy of Sciences

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