Professor | 许凌 | 数字化转型顾问

Name	许凌
Contact Information	xuling0502@mail.kiz.ac.cn
Language ability	中文, 英语
Province	云南

Name

许凌

Contact Information

xuling0502@mail.kiz.ac.cn

Language ability

中文, 英语

Province

云南

University/Lab Affiliation and Title	中国科学院大学
Faculty	Medical School
Academic Background & Achievements	2009-09--2014-07 学士: 华中农业大学 2009-09--2015-01 博士: 中国科学院大学
Work Experience	2018-01~现在 - 中国科学院昆明动物研究所 - 副研究员 2015-01~2017-12 - 中国科学院昆明动物研究所 - 助理研究员
Awards	中国免疫学会第七届青年学者奖 (2017): 一等奖

University/Lab Affiliation and Title

中国科学院大学

Faculty

Medical School

Academic Background & Achievements

2009-09--2014-07 学士: 华中农业大学
2009-09--2015-01 博士: 中国科学院大学

Work Experience

2018-01~现在 - 中国科学院昆明动物研究所 - 副研究员
2015-01~2017-12 - 中国科学院昆明动物研究所 - 助理研究员

Awards

中国免疫学会第七届青年学者奖 (2017): 一等奖

Areas of Focus	感染与免疫
Publications	A combination vaccine against SARS-CoV-2 and H1N1 influenza based on receptor binding domain trimerized by six-helix bundle fusion core, 第三作者, 2022 Specific inhibition of the NLRP3 inflammasome suppresses immune overactivation and alleviates COVID-19 like pathology in mice, 第四作者, 2022 Tupaia guanylate-binding protein 1 interacts with vesicular stomatitis virus phosphoprotein and represses primary transcription of the viral genome, 第三作者, 2021 Lower respiratory tract samples are reliable for severe acute respiratory syndrome coronavirus 2 nucleic acid diagnosis and animal model study, 第十作者, 2021 Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models, 第九作者, 2021 COVID-19-like symptoms observed in Chinese tree shrews infected with SARS-CoV-2, 第一作者, 2020 Tupaia OASL1 Promotes Cellular Antiviral Immune Responses by Recruiting MDA5 to MAVS, 第三作者, 2020 An Alternative Splicing of Tupaia STING Modulated Anti-RNA Virus Responses by Targeting MDA5-LGP2 and IRF3, 第一作者, 2020 Tupaia MAVS is a dual target during HCV infection for innate immune evasion and viral replication via NF-��B, 第一作者, 2020 Tupaia MAVS Is a Dual Target during Hepatitis C Virus Infection for Innate Immune Evasion and Viral Replication via NF-kappa B, 第一作者, 2020 Extracellular Vesicle-Mediated Delivery of Circular RNA SCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models, 第九作者, 2020 The 3��UTR of human MAVS mRNA contains multiple regulatory elements for the control of protein expression and subcellular localization, 第一作者, 2019 Establishment and characterization of an immortalized renal cell line of the Chinese tree shrew (Tupaia belangeri chinesis), 第四作者, 2019 Evolutionary selection on MDA5 and LGP2 in the chicken preserves antiviral competence in the absence of RIG-I, 第一作者, 2019 Molecular identification and antiviral function of the guanylate-binding protein (GBP) genes in the Chinese tree shrew (Tupaia belangeri chinesis), 第十一作者, 2019 The 3 ' UTR of human MAVS mRNA contains multiple regulatory elements for the control of protein expression and subcellular localization, 第一作者, 2019 Native musk and synthetic musk ketone strongly induced the growth repression and the apoptosis of cancer cells, 第一作者, 2016 Loss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew., 第一作者, 2016 Characterization of a MAVS ortholog from the Chinese tree shrew (Tupaia belangeri chinensis), 第一作者, 2015 Analysis of the complete mitochondrial genome and characterization of diverse NUMTs of Macaca leonina, 第三作者, 2015 IDH1 p.R132 mutations may not be actively involved in the carcinogenesis of hepatocellular carcinoma, 第三作者, 2014 树鼩进化分类地位的分子证据, 第一作者, 2013 GENETIC ENGINEERING NEURAL STEM CELL MODIFIED BY LENTIVIRUS FOR REPAIR OF SPINAL CORD INJURY IN RATS, 第六作者, 2006

Areas of Focus

感染与免疫

Publications

A combination vaccine against SARS-CoV-2 and H1N1 influenza based on receptor binding domain trimerized by six-helix bundle fusion core, 第三作者, 2022
Specific inhibition of the NLRP3 inflammasome suppresses immune overactivation and alleviates COVID-19 like pathology in mice, 第四作者, 2022
Tupaia guanylate-binding protein 1 interacts with vesicular stomatitis virus phosphoprotein and represses primary transcription of the viral genome, 第三作者, 2021
Lower respiratory tract samples are reliable for severe acute respiratory syndrome coronavirus 2 nucleic acid diagnosis and animal model study, 第十作者, 2021
Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models, 第九作者, 2021
COVID-19-like symptoms observed in Chinese tree shrews infected with SARS-CoV-2, 第一作者, 2020
Tupaia OASL1 Promotes Cellular Antiviral Immune Responses by Recruiting MDA5 to MAVS, 第三作者, 2020
An Alternative Splicing of Tupaia STING Modulated Anti-RNA Virus Responses by Targeting MDA5-LGP2 and IRF3, 第一作者, 2020
Tupaia MAVS is a dual target during HCV infection for innate immune evasion and viral replication via NF-��B, 第一作者, 2020
Tupaia MAVS Is a Dual Target during Hepatitis C Virus Infection for Innate Immune Evasion and Viral Replication via NF-kappa B, 第一作者, 2020
Extracellular Vesicle-Mediated Delivery of Circular RNA SCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models, 第九作者, 2020
The 3��UTR of human MAVS mRNA contains multiple regulatory elements for the control of protein expression and subcellular localization, 第一作者, 2019
Establishment and characterization of an immortalized renal cell line of the Chinese tree shrew (Tupaia belangeri chinesis), 第四作者, 2019
Evolutionary selection on MDA5 and LGP2 in the chicken preserves antiviral competence in the absence of RIG-I, 第一作者, 2019
Molecular identification and antiviral function of the guanylate-binding protein (GBP) genes in the Chinese tree shrew (Tupaia belangeri chinesis), 第十一作者, 2019
The 3 ' UTR of human MAVS mRNA contains multiple regulatory elements for the control of protein expression and subcellular localization, 第一作者, 2019
Native musk and synthetic musk ketone strongly induced the growth repression and the apoptosis of cancer cells, 第一作者, 2016
Loss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew., 第一作者, 2016
Characterization of a MAVS ortholog from the Chinese tree shrew (Tupaia belangeri chinensis), 第一作者, 2015
Analysis of the complete mitochondrial genome and characterization of diverse NUMTs of Macaca leonina, 第三作者, 2015
IDH1 p.R132 mutations may not be actively involved in the carcinogenesis of hepatocellular carcinoma, 第三作者, 2014
树鼩进化分类地位的分子证据, 第一作者, 2013
GENETIC ENGINEERING NEURAL STEM CELL MODIFIED BY LENTIVIRUS FOR REPAIR OF SPINAL CORD INJURY IN RATS, 第六作者, 2006

感染免疫 Sars-Cov-2 H1N1 Nlrp3炎症小体 Covid-19 树鼩 Mavs Hcv Nf-Κb

傅立峰 - 中国科学院大学

熊晓犁 - 中国科学院大学

Area of Focus
大分子结构: 蛋白质 | 结构 | 生物化学 | 分子生物学 | 大分子 | 结晶学 | 核磁共振 | 光谱学 | 建模 | 分析 | 流感病毒: 流感 | 病毒 | 感染 | 血凝素 | 神经氨酸酶 | 疫苗 | 大流行 | 传播 | 免疫 | 抗病毒 | 冠状病毒: Sars-Cov-2 | Covid-19 | 刺突蛋白 | 突变

吴超 - 南京大学

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