Areas of Focus
- Mucosal Immunity
- Tumor Immunity
- Autoimmune Diseases
- Immunodeficiency Diseases
Work Experience
- 2023-04 to Present - Chinese Academy of Sciences, Shanghai Institute of Nutrition and Health - Researcher
- 2017-04 to 2023-04 - National Institutes of Health, USA - Postdoctoral Fellow
- 2013-09 to 2017-03 - Chinese Academy of Sciences, Shanghai Institute of Life Sciences - Postdoctoral Fellow
Academic Background & Achievements
- 2008-09 to 2013-06 PhD: Chinese Academy of Sciences, Shanghai Institute of Life Sciences
Publications
- Mucus sialylation determines intestinal host-commensal homeostasis, Yikun Yao, 2022
- GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans, Yikun Yao, 2022
- Congenital iRHOM2 deficiency causes ADAM17 dysfunction and environmentally directed immunodysregulatory disease, Yikun Yao, 2022
- Homozygous IL37 mutation associated with infantile inflammatory bowel disease, Yikun Yao, 2021
- Efficient Immune Cell Genome Engineering with Enhanced CRISPR Editing Tools, Yikun Yao, 2021
- Two patients with chronic mucocutaneous candidiasis caused by TRAF3IP2 deficiency, Yikun Yao, 2021
- Dysregulated Microbiota-Driven Gasdermin D Activation Promotes Colitis Development by Mediating IL-18 Release, Yikun Yao, 2021
- Dectin-1-induced RIPK1 and RIPK3 activation protects host against Candida albicans infection, Yikun Yao, 2019
- Listeria hijacks host mitophagy through a novel mitophagy receptor to evade killing, Yikun Yao, 2019
- Iron Drives T Helper Cell Pathogenicity by Promoting RNA-Binding Protein PCBP1-Mediated Proinflammatory Cytokine Production, Yikun Yao, 2018
- USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein, Yikun Yao, 2018
- Antigen-specific CD8(+) T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin, Yikun Yao, 2017
- FGF2 cooperates with IL-17 to promote autoimmune inflammation, Yikun Yao, 2017
- Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage, Yikun Yao, 2015
- Expression regulation and function of NLRC5, Yikun Yao, 2013