Yikun Yao
Medical School
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English
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Mucosal Immunity Tumor Immunity Autoimmune Diseases Immunodeficiency Diseases Immune Response Pathogen Interaction Inflammation T Cells B Cells Cytokines
Areas of Focus
  • Mucosal Immunity
  • Tumor Immunity
  • Autoimmune Diseases
  • Immunodeficiency Diseases
Work Experience
  • 2023-04 to Present - Chinese Academy of Sciences, Shanghai Institute of Nutrition and Health - Researcher
  • 2017-04 to 2023-04 - National Institutes of Health, USA - Postdoctoral Fellow
  • 2013-09 to 2017-03 - Chinese Academy of Sciences, Shanghai Institute of Life Sciences - Postdoctoral Fellow
Academic Background & Achievements
  • 2008-09 to 2013-06 PhD: Chinese Academy of Sciences, Shanghai Institute of Life Sciences
Publications
  • Mucus sialylation determines intestinal host-commensal homeostasis, Yikun Yao, 2022
  • GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans, Yikun Yao, 2022
  • Congenital iRHOM2 deficiency causes ADAM17 dysfunction and environmentally directed immunodysregulatory disease, Yikun Yao, 2022
  • Homozygous IL37 mutation associated with infantile inflammatory bowel disease, Yikun Yao, 2021
  • Efficient Immune Cell Genome Engineering with Enhanced CRISPR Editing Tools, Yikun Yao, 2021
  • Two patients with chronic mucocutaneous candidiasis caused by TRAF3IP2 deficiency, Yikun Yao, 2021
  • Dysregulated Microbiota-Driven Gasdermin D Activation Promotes Colitis Development by Mediating IL-18 Release, Yikun Yao, 2021
  • Dectin-1-induced RIPK1 and RIPK3 activation protects host against Candida albicans infection, Yikun Yao, 2019
  • Listeria hijacks host mitophagy through a novel mitophagy receptor to evade killing, Yikun Yao, 2019
  • Iron Drives T Helper Cell Pathogenicity by Promoting RNA-Binding Protein PCBP1-Mediated Proinflammatory Cytokine Production, Yikun Yao, 2018
  • USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein, Yikun Yao, 2018
  • Antigen-specific CD8(+) T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin, Yikun Yao, 2017
  • FGF2 cooperates with IL-17 to promote autoimmune inflammation, Yikun Yao, 2017
  • Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage, Yikun Yao, 2015
  • Expression regulation and function of NLRC5, Yikun Yao, 2013
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