姚依昆
Medical School
中国科学院大学
上海
Language: 中文, 英文
Contact
黏膜免疫 肿瘤免疫 自身免疫性疾病 免疫缺陷疾病 免疫反应 病原体相互作用 炎症 T细胞 B细胞 细胞因子
Areas of Focus
  • 黏膜免疫
  • 肿瘤免疫
  • 自身免疫性疾病
  • 免疫缺陷疾病
Work Experience
  • 2023-04到现在 - 中国科学院上海营养与健康研究所 - 研究员
  • 2017-04到2023-04 - 美国国立卫生研究院 - 博士后
  • 2013-09到2017-03 - 中国科学院上海生命科学研究院 - 博士后
Academic Background & Achievements
  • 2008-09到2013-06 博士: 中国科学院上海生命科学研究院
Publications
  • Mucus sialylation determines intestinal host-commensal homeostasis, 姚依昆, 2022
  • GIMAP6 regulates autophagy, immune competence, and inflammation in mice and humans, 姚依昆, 2022
  • Congenital iRHOM2 deficiency causes ADAM17 dysfunction and environmentally directed immunodysregulatory disease, 姚依昆, 2022
  • Homozygous IL37 mutation associated with infantile inflammatory bowel disease, 姚依昆, 2021
  • Efficient Immune Cell Genome Engineering with Enhanced CRISPR Editing Tools, 姚依昆, 2021
  • Two patients with chronic mucocutaneous candidiasis caused by TRAF3IP2 deficiency, 姚依昆, 2021
  • Dysregulated Microbiota-Driven Gasdermin D Activation Promotes Colitis Development by Mediating IL-18 Release, 姚依昆, 2021
  • Dectin-1-induced RIPK1 and RIPK3 activation protects host against Candida albicans infection, 姚依昆, 2019
  • Listeria hijacks host mitophagy through a novel mitophagy receptor to evade killing, 姚依昆, 2019
  • Iron Drives T Helper Cell Pathogenicity by Promoting RNA-Binding Protein PCBP1-Mediated Proinflammatory Cytokine Production, 姚依昆, 2018
  • USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein, 姚依昆, 2018
  • Antigen-specific CD8(+) T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin, 姚依昆, 2017
  • FGF2 cooperates with IL-17 to promote autoimmune inflammation, 姚依昆, 2017
  • Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage, 姚依昆, 2015
  • Expression regulation and function of NLRC5, 姚依昆, 2013
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