Professor | Yin Wanchao | Asia Growth Partners

Name	Yin Wanchao
Contact Information	wcyin@simm.ac.cn
Language ability	Chinese, English
Province	Guangdong

Name

Yin Wanchao

Contact Information

wcyin@simm.ac.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2011-07 to 2017-07 PhD: Shanghai Institute of Materia Medica, Chinese Academy of Sciences 2004-09 to 2011-07 Bachelor's Degree: Soochow University
Work Experience	2022-01 to Present - Zhongshan Institute for Drug Innovation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher, Group Leader 2020-10 to 2021-12 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Associate Researcher 2020-08 to 2020-10 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Assistant Researcher 2017-07 to 2020-08 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Postdoctoral Researcher 2006-12 to 2008-12 - Qingdao Garrison, Marine Defense Regiment - Volunteer Soldier
Awards	Shanghai Youth May Fourth Medal (2023): Provincial Level 2023 Pudong New Area 'Mingzhu Elite Talent' (2023): Municipal Level Shanghai Pharmaceutical Science and Technology Award Youth Talent Award (2022): Provincial Level Outstanding Young Scientific Worker (2021): Institute Level Outstanding Communist Party Member (2021): Institute Level Sanofi 2021 Outstanding Young Scientific Talent (2021): Institute Level Shanghai 'Most Beautiful Retired Soldier' Nomination Award (2020): Provincial Level

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2011-07 to 2017-07 PhD: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
2004-09 to 2011-07 Bachelor's Degree: Soochow University

Work Experience

2022-01 to Present - Zhongshan Institute for Drug Innovation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher, Group Leader
2020-10 to 2021-12 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Associate Researcher
2020-08 to 2020-10 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Assistant Researcher
2017-07 to 2020-08 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Postdoctoral Researcher
2006-12 to 2008-12 - Qingdao Garrison, Marine Defense Regiment - Volunteer Soldier

Awards

Shanghai Youth May Fourth Medal (2023): Provincial Level
2023 Pudong New Area 'Mingzhu Elite Talent' (2023): Municipal Level
Shanghai Pharmaceutical Science and Technology Award Youth Talent Award (2022): Provincial Level
Outstanding Young Scientific Worker (2021): Institute Level
Outstanding Communist Party Member (2021): Institute Level
Sanofi 2021 Outstanding Young Scientific Talent (2021): Institute Level
Shanghai 'Most Beautiful Retired Soldier' Nomination Award (2020): Provincial Level

Areas of Focus	Structural Pharmacology
Publications	Molecular recognition of itch-associated neuropeptides by bombesin receptors, 11th Author, 2023 Structural insights into ligand recognition and activation of the medium-chain fatty acid-sensing receptor GPR84, 11th Author, 2023 A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors, 3rd Author, 2022 Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody, 1st Author, 2022 Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins, 11th Author, 2022 Molecular recognition of itch-associated neuropeptides by bombesin receptors, 11th Author, 2022 Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2, 2nd Author, 2021 Molecular basis for kinin selectivity and activation of the human bradykinin receptors, 11th Author, 2021 Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin, 1st Author, 2021 Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate, 3rd Author, 2021 Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir, 1st Author, 2020 A complex structure of arrestin-2 bound to a G protein-coupled receptor, 1st Author, 2019 Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist, 1st Author, 2018 5-HT1BR和拮抗剂及NTSR1和β-arrestin 1功能复合物的结构研究, 1st Author, 2017

Areas of Focus

Structural Pharmacology

Publications

Molecular recognition of itch-associated neuropeptides by bombesin receptors, 11th Author, 2023
Structural insights into ligand recognition and activation of the medium-chain fatty acid-sensing receptor GPR84, 11th Author, 2023
A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors, 3rd Author, 2022
Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody, 1st Author, 2022
Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins, 11th Author, 2022
Molecular recognition of itch-associated neuropeptides by bombesin receptors, 11th Author, 2022
Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2, 2nd Author, 2021
Molecular basis for kinin selectivity and activation of the human bradykinin receptors, 11th Author, 2021
Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin, 1st Author, 2021
Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate, 3rd Author, 2021
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir, 1st Author, 2020
A complex structure of arrestin-2 bound to a G protein-coupled receptor, 1st Author, 2019
Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist, 1st Author, 2018
5-HT1BR和拮抗剂及NTSR1和β-arrestin 1功能复合物的结构研究, 1st Author, 2017

Structural Biology Pharmacology Drug Design Gpcr Ligand Recognition Activation Mechanisms Sars-Cov-2 Inhibitors Cryo-Em Molecular Mechanisms

Wanqiu Li - Southern University of Science and Technology

Huaqiang Xu - University of Chinese Academy of Sciences

Ming-Yuan Su - Southern University of Science and Technology

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