Yijun Yan
Medical School
University of Chinese Academy of Sciences
Yunnan
Language: Chinese, English
Contact
Biosynthesis Natural Products Microbial Metabolites Biocatalysis Enzymes Engineering Synthetic Biology Gene Clusters Biotechnology
Areas of Focus
  • Natural Product Biosynthesis
  • Microbial Metabolites
  • Biocatalysis
  • Enzyme Engineering
  • Synthetic Biology
Work Experience
  • 2022-02~Present - Kunming Institute of Botany, Chinese Academy of Sciences - Researcher
  • 2017-01~2022-02 - Kunming Institute of Botany, Chinese Academy of Sciences - Associate Researcher
  • 2013-08~2016-12 - Kunming Institute of Botany, Chinese Academy of Sciences - Postdoctoral Researcher
Academic Background & Achievements
  • 2007-09--2013-07 Ph.D.: Northeast Agricultural University
  • 2003-09--2007-07 Bachelor's: Northeast Agricultural University
Publications
  • Characterization of Multifunctional and Non-stereoselective Oxidoreductase RubE7/IstO, Expanding the Functional Diversity of the Flavoenzyme Superfamily, Yan, Yijun, Yu, Zhiyin, Zhong, Wei, Hou, Xiaodong, Tao, Qiaoqiao, Cao, Minhang, Wang, Li, Cai, Xiaofeng, Rao, Yijian, Huang, ShengXiong, 2022
  • Biochemical and Metabolic Insights into Hyoscyamine Dehydrogenase, Qiu, Fei, Yan, Yijun, Zeng, Junlan, Huang, JianPing, Zeng, Lingjiang, Zhong, Wei, Lan, Xiaozhong, Chen, Min, Huang, ShengXiong, Liao, Zhihua, 2021
  • Taxonomic Characterization, and Secondary Metabolite Analysis of Streptomyces triticiradicis sp. nov.: A Novel Actinomycete with Antifungal Activity, Yu, Zhiyin, Han, Chuanyu, Yu, Bing, Zhao, Junwei, Yan, Yijun, Huang, Shengxiong, Liu, Chongxi, Xiang, Wensheng, 2020
  • Characterization of inthomycin biosynthetic gene cluster revealing new insights into carboxamide formation, Wang YongJiang, Wang Li, He Xin, Xu DongDong, Tang Jun, Ma YaTuan, Yan YiJun, Gu YuCheng, Yang Jing, Huang ShengXiong, 2020
  • Benwamycins A-G, Trialkyl-Substituted Benzene Derivatives from a Soil-Derived Streptomyces, Yang, FengXian, Huang, JianPing, Liu, Zhixiang, Wang, Zhiyan, Yang, Jing, Tang, Jun, Yu, Zhiyin, Yan, Yijun, Kai, Guoyin, Huang, ShengXiong, 2020
  • Biosynthetic access to the rare antiarose sugar via an unusual reductase-epimerase, Yan, Yijun, Yang, Jing, Wang, Li, Xu, Dongdong, Yu, Zhiyin, Guo, Xiaowei, Horsman, Geoff P, Lin, Shuangjun, Tao, Meifeng, Huang, ShengXiong, 2020
  • Naphthomycin-derived macrolactams with two new carbon skeletons from endophytic Streptomyces, Zhang, Zhouxin, Cao, Pei, Shang, NingNing, Yang, Jing, Wang, Li, Yan, Yijun, Huang, ShengXiong, 2019
  • Characterization of the N-methyltransferases involved in the biosynthesis of toxoflavin, fervenulin and reumycin from Streptomyces hiroshimensis ATCC53615, Su, Can, Yan, Yijun, Guo, Xiaowei, Luo, Jianying, Liu, Chongxi, Zhang, Zhouxin, Xiang, WenSheng, Huang, ShengXiong, 2019
  • A new actinomycin Z analogue with an additional oxygen bridge between chromophore and beta-depsipentapeptide from Streptomyces sp. KIB-H714, Dong, Miao, Cao, Pei, Ma, YaTuan, Luo, Jianying, Yan, Yijun, Li, RongTao, Huang, ShengXiong, 2019
  • Isolation and biosynthesis of labdanmycins: four new labdane diterpenes from endophytic Streptomyces, Wang, Li, Yan, Yijun, Huang, Jianping, Xiong, Zi-Jun, Yang, Jing, Li, Jie, Huang, Sheng-Xiong, Wang, Zhiyan, Luo, Jianying, 2018
  • New phenoxazinone-related alkaloids from strain Streptomyces sp KIB-H1318, Yang, FengXian, Hou, GuanXiong, Luo, Jianying, Yang, Jing, Yan, Yijun, Huang, ShengXiong, 2018
  • Glycosylated piericidins from an endophytic streptomyces with cytotoxicity and antimicrobial activity, Shang, NingNing, Zhang, Zhouxin, Huang, JianPing, Wang, Li, Luo, Jianying, Yang, Jing, Peng, Teng, Yan, Yijun, Ma, YaTuan, Huang, ShengXiong, 2018
  • New phenoxazinone-related alkaloids from strain Streptomyces sp KIB-H1318, Huang, Sheng-Xiong, Yang, Feng-Xian, Luo, Jianying, Hou, Guan-Xiong, Yang, Jing, Yan, Yijun, 2018
  • Glycosylated piericidins from an endophytic streptomyces with cytotoxicity and antimicrobial activity, Yang, Jing, Peng, Teng, Yan, Yijun, Huang, Sheng-Xiong, Ma, Ya-Tuan, Shang, Ning-Ning, Zhang, Zhouxin, Huang, Jian-Ping, Wang, Li, Luo, Jianying, 2018
  • Isolation and biosynthesis of labdanmycins: four new labdane diterpenes from endophytic Streptomyces, Xiong, ZiJun, Huang, Jianping, Yan, Yijun, Wang, Li, Wang, Zhiyan, Yang, Jing, Luo, Jianying, Li, Jie, Huang, ShengXiong, 2018
  • Natural and Semisynthetic Tigliane Diterpenoids with New Carbon Skeletons from Euphorbia dracunculoides as a Wnt Signaling Pathway Inhibitor, Wang, Li, Yang, Jing, Kong, LingMei, Deng, Jun, Xiong, Zijun, Huang, Jianping, Luo, Jianping, Yan, Yijun, Hu, Yikao, Li, XiaoNian, Li, Yan, Zhao, Yong, Huang, ShengXiong, 2017
  • Lorneic Acid Analogues from an Endophytic Actinomycete, Yang, Ruimin, Yang, Jing, Wang, Li, Huang, JianPing, Xiong, Zijun, Luo, Jianying, Yu, Mingming, Yan, Yijun, Huang, ShengXiong, 2017
  • α-Pyrone Derivatives from a Streptomyces Strain Resensitize Tamoxifen Resistance in Breast Cancer Cells, RuiMin Yang, XiuLei Zhang, Li Wang, JianPing Huang, Jing Yang, YiJun Yan, JianYing Luo, XiangTing Wang, ShengXiong Huang, 2017
  • Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids, Yijun Yan, Jing Yang, Zhiyin Yu, Mingming Yu, YaTuan Ma, Li Wang, Can Su, Jianying Luo, Geoffrey P Horsman, ShengXiong Huang, 2016
  • Tropolone Ring Construction in the Biosynthesis of Rubrolone B, a Cationic Tropolone Alkaloid from Endophytic Streptomyces, Yan, Yijun, Ma, YaTuan, Yang, Jing, Horsman, Geoff P, Luo, Dan, Ji, Xu, Huang, ShengXiong, 2016
  • A new antifungal macrolide from Streptomyces sp KIB-H869 and structure revision of halichomycin, Yu, Zhiyin, Wang, Li, Yang, Jing, Zhang, Fan, Sun, Yun, Yu, Mingming, Yan, Yijun, Ma, YaTuan, Huang, ShengXiong, 2016
  • 土壤来源链霉菌KIB-H91次级代谢产物的分离鉴定, 喻明明, 苏灿, 马亚团, 颜一军, 黄胜雄, 薛大权, 2015
  • Designed biosynthesis of 25-methyl and 25-ethyl ivermectin with enhanced insecticidal activity by domain swap of avermectin polyketide synthase, Zhang, Ji, Yan, YiJun, An, Jing, Huang, ShengXiong, Wang, XiangJing, Xiang, WenSheng, 2015
  • New Duclauxamide from Penicillium manginii YIM PH30375 and Structure Revision of the Duclauxin Family, Cao, Pei, Yang, Jing, Miao, CuiPing, Yan, Yijun, Ma, YaTuan, Li, XiaoNian, Zhao, LiXing, Huang, ShengXiong, 2015
  • Neaumycin - A New Macrolide from Streptomyces sp. NEAU-x211, Huang Sheng-Xiong, Wang Xiang-Jing, Yan Yijun, Wang Ji-Dong, Zhang Ji, Liu Cong-Xi, Xiang Wen-Sheng, Shen Ben, 2012
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