Professor | Yijun Yan | Asia Growth Partners

Name	Yijun Yan
Contact Information	yanyijun@mail.kib.ac.cn
Language ability	Chinese, English
Province	Yunnan

Name

Yijun Yan

Contact Information

yanyijun@mail.kib.ac.cn

Language ability

Chinese, English

Province

Yunnan

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2007-09--2013-07 Ph.D.: Northeast Agricultural University 2003-09--2007-07 Bachelor's: Northeast Agricultural University
Work Experience	2022-02~Present - Kunming Institute of Botany, Chinese Academy of Sciences - Researcher 2017-01~2022-02 - Kunming Institute of Botany, Chinese Academy of Sciences - Associate Researcher 2013-08~2016-12 - Kunming Institute of Botany, Chinese Academy of Sciences - Postdoctoral Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2007-09--2013-07 Ph.D.: Northeast Agricultural University
2003-09--2007-07 Bachelor's: Northeast Agricultural University

Work Experience

2022-02~Present - Kunming Institute of Botany, Chinese Academy of Sciences - Researcher
2017-01~2022-02 - Kunming Institute of Botany, Chinese Academy of Sciences - Associate Researcher
2013-08~2016-12 - Kunming Institute of Botany, Chinese Academy of Sciences - Postdoctoral Researcher

Areas of Focus	Natural Product Biosynthesis Microbial Metabolites Biocatalysis Enzyme Engineering Synthetic Biology
Publications	Characterization of Multifunctional and Non-stereoselective Oxidoreductase RubE7/IstO, Expanding the Functional Diversity of the Flavoenzyme Superfamily, Yan, Yijun, Yu, Zhiyin, Zhong, Wei, Hou, Xiaodong, Tao, Qiaoqiao, Cao, Minhang, Wang, Li, Cai, Xiaofeng, Rao, Yijian, Huang, ShengXiong, 2022 Biochemical and Metabolic Insights into Hyoscyamine Dehydrogenase, Qiu, Fei, Yan, Yijun, Zeng, Junlan, Huang, JianPing, Zeng, Lingjiang, Zhong, Wei, Lan, Xiaozhong, Chen, Min, Huang, ShengXiong, Liao, Zhihua, 2021 Taxonomic Characterization, and Secondary Metabolite Analysis of Streptomyces triticiradicis sp. nov.: A Novel Actinomycete with Antifungal Activity, Yu, Zhiyin, Han, Chuanyu, Yu, Bing, Zhao, Junwei, Yan, Yijun, Huang, Shengxiong, Liu, Chongxi, Xiang, Wensheng, 2020 Characterization of inthomycin biosynthetic gene cluster revealing new insights into carboxamide formation, Wang YongJiang, Wang Li, He Xin, Xu DongDong, Tang Jun, Ma YaTuan, Yan YiJun, Gu YuCheng, Yang Jing, Huang ShengXiong, 2020 Benwamycins A-G, Trialkyl-Substituted Benzene Derivatives from a Soil-Derived Streptomyces, Yang, FengXian, Huang, JianPing, Liu, Zhixiang, Wang, Zhiyan, Yang, Jing, Tang, Jun, Yu, Zhiyin, Yan, Yijun, Kai, Guoyin, Huang, ShengXiong, 2020 Biosynthetic access to the rare antiarose sugar via an unusual reductase-epimerase, Yan, Yijun, Yang, Jing, Wang, Li, Xu, Dongdong, Yu, Zhiyin, Guo, Xiaowei, Horsman, Geoff P, Lin, Shuangjun, Tao, Meifeng, Huang, ShengXiong, 2020 Naphthomycin-derived macrolactams with two new carbon skeletons from endophytic Streptomyces, Zhang, Zhouxin, Cao, Pei, Shang, NingNing, Yang, Jing, Wang, Li, Yan, Yijun, Huang, ShengXiong, 2019 Characterization of the N-methyltransferases involved in the biosynthesis of toxoflavin, fervenulin and reumycin from Streptomyces hiroshimensis ATCC53615, Su, Can, Yan, Yijun, Guo, Xiaowei, Luo, Jianying, Liu, Chongxi, Zhang, Zhouxin, Xiang, WenSheng, Huang, ShengXiong, 2019 A new actinomycin Z analogue with an additional oxygen bridge between chromophore and beta-depsipentapeptide from Streptomyces sp. KIB-H714, Dong, Miao, Cao, Pei, Ma, YaTuan, Luo, Jianying, Yan, Yijun, Li, RongTao, Huang, ShengXiong, 2019 Isolation and biosynthesis of labdanmycins: four new labdane diterpenes from endophytic Streptomyces, Wang, Li, Yan, Yijun, Huang, Jianping, Xiong, Zi-Jun, Yang, Jing, Li, Jie, Huang, Sheng-Xiong, Wang, Zhiyan, Luo, Jianying, 2018 New phenoxazinone-related alkaloids from strain Streptomyces sp KIB-H1318, Yang, FengXian, Hou, GuanXiong, Luo, Jianying, Yang, Jing, Yan, Yijun, Huang, ShengXiong, 2018 Glycosylated piericidins from an endophytic streptomyces with cytotoxicity and antimicrobial activity, Shang, NingNing, Zhang, Zhouxin, Huang, JianPing, Wang, Li, Luo, Jianying, Yang, Jing, Peng, Teng, Yan, Yijun, Ma, YaTuan, Huang, ShengXiong, 2018 New phenoxazinone-related alkaloids from strain Streptomyces sp KIB-H1318, Huang, Sheng-Xiong, Yang, Feng-Xian, Luo, Jianying, Hou, Guan-Xiong, Yang, Jing, Yan, Yijun, 2018 Glycosylated piericidins from an endophytic streptomyces with cytotoxicity and antimicrobial activity, Yang, Jing, Peng, Teng, Yan, Yijun, Huang, Sheng-Xiong, Ma, Ya-Tuan, Shang, Ning-Ning, Zhang, Zhouxin, Huang, Jian-Ping, Wang, Li, Luo, Jianying, 2018 Isolation and biosynthesis of labdanmycins: four new labdane diterpenes from endophytic Streptomyces, Xiong, ZiJun, Huang, Jianping, Yan, Yijun, Wang, Li, Wang, Zhiyan, Yang, Jing, Luo, Jianying, Li, Jie, Huang, ShengXiong, 2018 Natural and Semisynthetic Tigliane Diterpenoids with New Carbon Skeletons from Euphorbia dracunculoides as a Wnt Signaling Pathway Inhibitor, Wang, Li, Yang, Jing, Kong, LingMei, Deng, Jun, Xiong, Zijun, Huang, Jianping, Luo, Jianping, Yan, Yijun, Hu, Yikao, Li, XiaoNian, Li, Yan, Zhao, Yong, Huang, ShengXiong, 2017 Lorneic Acid Analogues from an Endophytic Actinomycete, Yang, Ruimin, Yang, Jing, Wang, Li, Huang, JianPing, Xiong, Zijun, Luo, Jianying, Yu, Mingming, Yan, Yijun, Huang, ShengXiong, 2017 α-Pyrone Derivatives from a Streptomyces Strain Resensitize Tamoxifen Resistance in Breast Cancer Cells, RuiMin Yang, XiuLei Zhang, Li Wang, JianPing Huang, Jing Yang, YiJun Yan, JianYing Luo, XiangTing Wang, ShengXiong Huang, 2017 Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids, Yijun Yan, Jing Yang, Zhiyin Yu, Mingming Yu, YaTuan Ma, Li Wang, Can Su, Jianying Luo, Geoffrey P Horsman, ShengXiong Huang, 2016 Tropolone Ring Construction in the Biosynthesis of Rubrolone B, a Cationic Tropolone Alkaloid from Endophytic Streptomyces, Yan, Yijun, Ma, YaTuan, Yang, Jing, Horsman, Geoff P, Luo, Dan, Ji, Xu, Huang, ShengXiong, 2016 A new antifungal macrolide from Streptomyces sp KIB-H869 and structure revision of halichomycin, Yu, Zhiyin, Wang, Li, Yang, Jing, Zhang, Fan, Sun, Yun, Yu, Mingming, Yan, Yijun, Ma, YaTuan, Huang, ShengXiong, 2016 土壤来源链霉菌KIB-H91次级代谢产物的分离鉴定, 喻明明, 苏灿, 马亚团, 颜一军, 黄胜雄, 薛大权, 2015 Designed biosynthesis of 25-methyl and 25-ethyl ivermectin with enhanced insecticidal activity by domain swap of avermectin polyketide synthase, Zhang, Ji, Yan, YiJun, An, Jing, Huang, ShengXiong, Wang, XiangJing, Xiang, WenSheng, 2015 New Duclauxamide from Penicillium manginii YIM PH30375 and Structure Revision of the Duclauxin Family, Cao, Pei, Yang, Jing, Miao, CuiPing, Yan, Yijun, Ma, YaTuan, Li, XiaoNian, Zhao, LiXing, Huang, ShengXiong, 2015 Neaumycin - A New Macrolide from Streptomyces sp. NEAU-x211, Huang Sheng-Xiong, Wang Xiang-Jing, Yan Yijun, Wang Ji-Dong, Zhang Ji, Liu Cong-Xi, Xiang Wen-Sheng, Shen Ben, 2012

Areas of Focus

Natural Product Biosynthesis
Microbial Metabolites
Biocatalysis
Enzyme Engineering
Synthetic Biology

Publications

Characterization of Multifunctional and Non-stereoselective Oxidoreductase RubE7/IstO, Expanding the Functional Diversity of the Flavoenzyme Superfamily, Yan, Yijun, Yu, Zhiyin, Zhong, Wei, Hou, Xiaodong, Tao, Qiaoqiao, Cao, Minhang, Wang, Li, Cai, Xiaofeng, Rao, Yijian, Huang, ShengXiong, 2022
Biochemical and Metabolic Insights into Hyoscyamine Dehydrogenase, Qiu, Fei, Yan, Yijun, Zeng, Junlan, Huang, JianPing, Zeng, Lingjiang, Zhong, Wei, Lan, Xiaozhong, Chen, Min, Huang, ShengXiong, Liao, Zhihua, 2021
Taxonomic Characterization, and Secondary Metabolite Analysis of Streptomyces triticiradicis sp. nov.: A Novel Actinomycete with Antifungal Activity, Yu, Zhiyin, Han, Chuanyu, Yu, Bing, Zhao, Junwei, Yan, Yijun, Huang, Shengxiong, Liu, Chongxi, Xiang, Wensheng, 2020
Characterization of inthomycin biosynthetic gene cluster revealing new insights into carboxamide formation, Wang YongJiang, Wang Li, He Xin, Xu DongDong, Tang Jun, Ma YaTuan, Yan YiJun, Gu YuCheng, Yang Jing, Huang ShengXiong, 2020
Benwamycins A-G, Trialkyl-Substituted Benzene Derivatives from a Soil-Derived Streptomyces, Yang, FengXian, Huang, JianPing, Liu, Zhixiang, Wang, Zhiyan, Yang, Jing, Tang, Jun, Yu, Zhiyin, Yan, Yijun, Kai, Guoyin, Huang, ShengXiong, 2020
Biosynthetic access to the rare antiarose sugar via an unusual reductase-epimerase, Yan, Yijun, Yang, Jing, Wang, Li, Xu, Dongdong, Yu, Zhiyin, Guo, Xiaowei, Horsman, Geoff P, Lin, Shuangjun, Tao, Meifeng, Huang, ShengXiong, 2020
Naphthomycin-derived macrolactams with two new carbon skeletons from endophytic Streptomyces, Zhang, Zhouxin, Cao, Pei, Shang, NingNing, Yang, Jing, Wang, Li, Yan, Yijun, Huang, ShengXiong, 2019
Characterization of the N-methyltransferases involved in the biosynthesis of toxoflavin, fervenulin and reumycin from Streptomyces hiroshimensis ATCC53615, Su, Can, Yan, Yijun, Guo, Xiaowei, Luo, Jianying, Liu, Chongxi, Zhang, Zhouxin, Xiang, WenSheng, Huang, ShengXiong, 2019
A new actinomycin Z analogue with an additional oxygen bridge between chromophore and beta-depsipentapeptide from Streptomyces sp. KIB-H714, Dong, Miao, Cao, Pei, Ma, YaTuan, Luo, Jianying, Yan, Yijun, Li, RongTao, Huang, ShengXiong, 2019
Isolation and biosynthesis of labdanmycins: four new labdane diterpenes from endophytic Streptomyces, Wang, Li, Yan, Yijun, Huang, Jianping, Xiong, Zi-Jun, Yang, Jing, Li, Jie, Huang, Sheng-Xiong, Wang, Zhiyan, Luo, Jianying, 2018
New phenoxazinone-related alkaloids from strain Streptomyces sp KIB-H1318, Yang, FengXian, Hou, GuanXiong, Luo, Jianying, Yang, Jing, Yan, Yijun, Huang, ShengXiong, 2018
Glycosylated piericidins from an endophytic streptomyces with cytotoxicity and antimicrobial activity, Shang, NingNing, Zhang, Zhouxin, Huang, JianPing, Wang, Li, Luo, Jianying, Yang, Jing, Peng, Teng, Yan, Yijun, Ma, YaTuan, Huang, ShengXiong, 2018
New phenoxazinone-related alkaloids from strain Streptomyces sp KIB-H1318, Huang, Sheng-Xiong, Yang, Feng-Xian, Luo, Jianying, Hou, Guan-Xiong, Yang, Jing, Yan, Yijun, 2018
Glycosylated piericidins from an endophytic streptomyces with cytotoxicity and antimicrobial activity, Yang, Jing, Peng, Teng, Yan, Yijun, Huang, Sheng-Xiong, Ma, Ya-Tuan, Shang, Ning-Ning, Zhang, Zhouxin, Huang, Jian-Ping, Wang, Li, Luo, Jianying, 2018
Isolation and biosynthesis of labdanmycins: four new labdane diterpenes from endophytic Streptomyces, Xiong, ZiJun, Huang, Jianping, Yan, Yijun, Wang, Li, Wang, Zhiyan, Yang, Jing, Luo, Jianying, Li, Jie, Huang, ShengXiong, 2018
Natural and Semisynthetic Tigliane Diterpenoids with New Carbon Skeletons from Euphorbia dracunculoides as a Wnt Signaling Pathway Inhibitor, Wang, Li, Yang, Jing, Kong, LingMei, Deng, Jun, Xiong, Zijun, Huang, Jianping, Luo, Jianping, Yan, Yijun, Hu, Yikao, Li, XiaoNian, Li, Yan, Zhao, Yong, Huang, ShengXiong, 2017
Lorneic Acid Analogues from an Endophytic Actinomycete, Yang, Ruimin, Yang, Jing, Wang, Li, Huang, JianPing, Xiong, Zijun, Luo, Jianying, Yu, Mingming, Yan, Yijun, Huang, ShengXiong, 2017
α-Pyrone Derivatives from a Streptomyces Strain Resensitize Tamoxifen Resistance in Breast Cancer Cells, RuiMin Yang, XiuLei Zhang, Li Wang, JianPing Huang, Jing Yang, YiJun Yan, JianYing Luo, XiangTing Wang, ShengXiong Huang, 2017
Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids, Yijun Yan, Jing Yang, Zhiyin Yu, Mingming Yu, YaTuan Ma, Li Wang, Can Su, Jianying Luo, Geoffrey P Horsman, ShengXiong Huang, 2016
Tropolone Ring Construction in the Biosynthesis of Rubrolone B, a Cationic Tropolone Alkaloid from Endophytic Streptomyces, Yan, Yijun, Ma, YaTuan, Yang, Jing, Horsman, Geoff P, Luo, Dan, Ji, Xu, Huang, ShengXiong, 2016
A new antifungal macrolide from Streptomyces sp KIB-H869 and structure revision of halichomycin, Yu, Zhiyin, Wang, Li, Yang, Jing, Zhang, Fan, Sun, Yun, Yu, Mingming, Yan, Yijun, Ma, YaTuan, Huang, ShengXiong, 2016
土壤来源链霉菌KIB-H91次级代谢产物的分离鉴定, 喻明明, 苏灿, 马亚团, 颜一军, 黄胜雄, 薛大权, 2015
Designed biosynthesis of 25-methyl and 25-ethyl ivermectin with enhanced insecticidal activity by domain swap of avermectin polyketide synthase, Zhang, Ji, Yan, YiJun, An, Jing, Huang, ShengXiong, Wang, XiangJing, Xiang, WenSheng, 2015
New Duclauxamide from Penicillium manginii YIM PH30375 and Structure Revision of the Duclauxin Family, Cao, Pei, Yang, Jing, Miao, CuiPing, Yan, Yijun, Ma, YaTuan, Li, XiaoNian, Zhao, LiXing, Huang, ShengXiong, 2015
Neaumycin - A New Macrolide from Streptomyces sp. NEAU-x211, Huang Sheng-Xiong, Wang Xiang-Jing, Yan Yijun, Wang Ji-Dong, Zhang Ji, Liu Cong-Xi, Xiang Wen-Sheng, Shen Ben, 2012

Biosynthesis Natural Products Microbial Metabolites Biocatalysis Enzymes Engineering Synthetic Biology Gene Clusters Biotechnology

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