Areas of Focus
- Pharmaceutical Chemistry
- Pharmacology
- Chemical Biology
Work Experience
- 1996-10~Present - Chinese Academy of Sciences, Chengdu Institute of Biology - Researcher (1997)
- 1987-06~1990-09 - Chinese Academy of Sciences, Chengdu Institute of Biology - Assistant Researcher (1989)
Academic Background & Achievements
- 1995-01--1996-10 Postdoctoral: Peking University, College of Chemistry and Molecular Engineering
- 1993-09--1994-12 Postdoctoral: University of Bonn, Institute of Pharmaceutical Research
- 1990-09--1993-09 PhD: University of Bonn, Institute of Pharmaceutical Research
- 1984-09--1987-06 Master's: Lanzhou University, Department of Chemistry
- 1980-09--1984-07 Bachelor's: Sichuan University, Department of Chemistry
Publications
- Diterpenes from Dysoxylum lukii Merr, Guolin Zhang, 2019
- Metal Ion Coordination Protocol for the Synthesis 2,3-Dehydrosilybin and 19-O-Demethyl-2,3-dehydrosilybin from Silybin and Their Antitumor Activities, Guolin Zhang, 2018
- Cytotoxic Lanostane-type C31 Triterpeniod Derivatives from the Fruiting Bodies of Cultivated Fomitopsis palustris, Guolin Zhang, 2018
- Inhibition of TPL2 by interferon-α suppresses bladder cancer through activation of PDE4D, Guolin Zhang, 2018
- Synthesis of 5-subsituted flavonols via Algar-Flynn-Oyamada (AFO) reaction: the mechanistic implication, Guolin Zhang, 2017
- 6-Hydroxy-3-O-methyl-kaempferol 6-O-glucopyranoside potentiates the antiproliferative effect of interferon α/β by promoting the activation of JAK/STAT signaling through the inhibition of SOCS3 in hepatocellular carcinoma cells, Guolin Zhang, 2017
- Two new alkaloids from Melodinus hemsleyanus, Guolin Zhang, 2016
- Iridoid glucosides and diterpenoids from Caryopteris glutinosa, Guolin Zhang, 2016
- 2-Phenylbenzo[b]furans: synthesis and promoting activity on estrogen biosynthesis, Guolin Zhang, 2016
- Synthesis of icariin from kaempferol through regioselective methylation and para-Claisen-Cope rearrangement, Guolin Zhang, 2015
- Antioxidant compounds from ethanol extracts of bamboo (Neosinocalamus affinis) leaves, Guolin Zhang, 2015
- Selective methylation of kaempferol via benzylation and deacetylation of kaempferol acetates, Guolin Zhang, 2015
- Novel Stilbenes from Artocarpus nanchuanensis, Guolin Zhang, 2015
- Analysis of sesquiterpene pyridine alkaloids using ESI–MS/MS: The product ion at m/z 310 formed by an ion–dipole intermediate, Guolin Zhang, 2015
- Untargeted analysis of sesquiterpene pyridine alkaloids from the dried roots of Tripterygium wilfordii using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry, Guolin Zhang, 2015
- Copper-Catalyzed Decarboxylative Intramolecular C-O Coupling: Synthesis of 2-Arylbenzofuran from 3-Arylcoumarin, Guolin Zhang, 2014
- Luteolin Sensitizes the Antiproliferative Effect of Interferon α/β by Activation of JAK/STAT Pathway through PKA-Mediated Inhibition of SHP-2 in cancer cells, Guolin Zhang, 2014
- Two natural products, trans-phytol and (22E)-ergosta-6,9,22-triene-3β,5α,8α-triol, inhibit the biosynthesis of estrogen in human ovarian granulosa cells by aromatase (CYP19), Guolin Zhang, 2014
- Nitrogen-containing dihydro-β-agarofuran derivatives mined from the dried roots of Tripterygium wilfordii, Guolin Zhang, 2014
- 3-Arylcoumarins Synthesis and potent anti-inflammatory activity, Guolin Zhang, 2014
- Bioactivity-guided isolation of antiosteoporotic compounds from Ligustrum lucidum, Guolin Zhang, 2013
- Icariin from Epimedium brevicornum Maxim promotes the biosynthesis of estrogen by aromatase (CYP19), Guolin Zhang, 2013
- Pregnane alkaloids from Sarcococca hookeriana var digyna, Guolin Zhang, 2013
- Anti-inflammatory phenanthrene derivatives from stems of Dendrobium denneanum, Guolin Zhang, 2013
- Endophytic fungus Trichoderma atroviride LY357: Isolation, identification, and camptothecin production, Guolin Zhang, 2013
- Inhibitory effect of luteolin on estrogen biosynthesis in human ovarian granulosa cells by suppression of aromatase (CYP19), Guolin Zhang, 2012
- Egonol gentiobioside and egonol gentiotrioside from Styrax perkinsiae promote the biosynthesis of estrogen by aromatase, Guolin Zhang, 2012
- Chaetoconvosins A and B, Alkaloids with new skeleton from fungus Chaetomium convolutum, Guolin Zhang, 2012
- Analysis of cipadesin limonoids from Cipadessa cinerascens using electrospray ionization quadrupole time-of-flight tandem mass spectrometry and quantum chemical calculations, Guolin Zhang, 2012
- Identification of small molecule activators of the Janus kinase/signal transducer and activator of transcription pathway using a cell-based screening, Guolin Zhang, 2012
- Dihydroagarofurna derivatives from dried roots of Tripterygium wilfordii, Guolin Zhang, 2012
- Toxicity of raw and processed roots of Polygonum multiflorum, Guolin Zhang, 2012
- Three new eudesmanolides from Camchaya loloana, Guolin Zhang, 2011
- Antiosteoporotic compounds from seeds of Cuscuta chinensis, Guolin Zhang, 2011
- Chromones and coumarins from the dried fructus of Cnidium monnieri, Guolin Zhang, 2011
- Four New Alkaloids, Brevianamides O–R, from the fungus Aspergillus versicolor, Guolin Zhang, 2010
- Brevianamide J, a new indole alkaloid dimer from fungus Aspergillus versicolor, Guolin Zhang, 2009
- Analysis of epipolythiodioxopiperazines in fungus Chaetomium cochliodes using HPLC-ESI-MS/MS/MS, Guolin Zhang, 2008
- Preparation of two diastereomeric decalins synthons and (-)-ambrox, Guolin Zhang, 2008
- Electrospray tandem mass spectrometry of epipolythiodioxopiperazines, Guolin Zhang, 2007
- Abietane lactones and iridoids from Goldfussia yunnanensis, Guolin Zhang, 2007
- Lupane triterpenoids and a diarylhenpoid from Clematoclethra actinidioides, Guolin Zhang, 2006
- Chaetoindicins A-C, three isoquinoline alkaloids from fungus Chaetomium indicum, Guolin Zhang, 2006
- Synthesis of 4-chloromethyl-2-aryl-5- methyloxazoles, Guolin Zhang, 2006
- Chaetocochins A-C: three polythiodioxopiperazines from Chaetomium cochliodes, Guolin Zhang, 2006
- Chiral decalins: preparation from oleanolic acid and application in the synthesis of (-)-9-epi-ambrox, Guolin Zhang, 2006
- Phenolic and Triterpene Glycosides from the Stems of Ilex litseaefolia, Guolin Zhang, 2005
- Novel cadinane and norcadinane sesquiterpenes from Goldfussia psilostachys, Guolin Zhang, 2005
- Two diterpenes and three diterpene glucosides from Philogacanthus curviflorus, Guolin Zhang, 2005
- Synthesis of
Awards
- Sichuan Provincial Science and Technology Progress Award, First Prize, Provincial Level, 2013
