2005-09--2008-06 PhD: Institute of Microbiology, Chinese Academy of Sciences
2002-09--2005-06 Master's: China Agricultural University
1998-09--2002-06 Bachelor's: China Agricultural University
2008-07~Present - Institute of Microbiology, Chinese Academy of Sciences - PhD
L-threonine, L-methionine, and L-serine genetic engineering bacteria construction and fermentation condition optimization (2016): City-level
Key technologies and industrial application of lysine and threonine industrial production bacteria transformation (2014): Second Prize, Ministry-level
Research
Biosynthesis and metabolic regulation of important biological agents Microbial metabolic engineering and systems biology New methods and technologies in synthetic biology
SHMT2 promotes cell viability and inhibits ROS-dependent, mitochondrial-mediated apoptosis via the intrinsic signaling pathway in bladder cancer cells., Yun Zhang, Zhe Liu, Xueliang Wang, Hui Jian, Haihan Xiao, Tingyi Wen, 2022
Model-Guided Metabolic Rewiring for Gamma-Aminobutyric Acid and Butyrolactam Biosynthesis in Corynebacterium glutamicum ATCC13032., Yun Zhang, Jing Zhao, Xueliang Wang, Yuan Tang, Shuwen Liu, Tingyi Wen, 2022
Zeolitic imidazolate framework-based nanoparticles for the cascade enhancement of cancer chemodynamic therapy by targeting glutamine metabolism., Hui Jian, Yun Zhang, Junyue Wang, Zhenxiang Chen, Tingyi Wen, 2022
High-throughput sequencing unravels the cell heterogeneity of cerebrospinal fluid in the bacterial meningitis of children., Haihan Xiao, Haijuan Xiao, Yun Zhang, Lingyun Guo, Zhenzhen Dou, Wenya Feng, Linlin Liu, Bing Liu, Tianming Chen, Gang Liu, Tingyi Wen, 2022
整合组学的代谢网络模型研究进展., 张芸, 2021
Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy-Darabino- heptulosonate-7-phosphate synthase from Escherichia coli., Yun Zhang, 2019
Reconstruction of TCA cycle in Corynebacterium glutamicum with a genome-scale metabolic network model for trans-4-hydroxyproline production., Yu Zhang, Yun Zhang, Bo Wang, Xiuling Shang, Qitiao Hu, Shuwen Liu, Tingyi Wen, 2019
A seamless and iterative DNA assembly method named PS-Brick and its assisted metabolic engineering for threonine and 1-propanol production., Shuwen Liu, Haihan Xiao, Fangfang Zhang, Zheng Lu, Yun Zhang, Aihua Deng, Zhongcai Li, Cui Yang, Tingyi Wen, 2019
Bacterial Genome Editing via a Designed Toxin-Antitoxin Cassette., Jie Wu, Aihua Deng, Qinyun Sun, Hua Bai, Zhaopeng Sun, Xiuling Shang, Yun Zhang, Qan Liu, Yong Liang, Shuwen Liu, Yongsheng Che, Tingyi Wen, 2018
A Novel Tool for Microbial Genome Editing Using the Restriction-Modification System., Hua Bai, Aihua Deng, Shuwen Liu, Di Cui, Qidi Qiu, Laiyou Wang, Zhao Yang, Jie Wu, Xiuling Shang, Yun Zhang, Tingyi Wen, 2018
Reprogramming One-Carbon Metabolic Pathways To Decouple L-Serine Catabolism from Cell Growth in Corynebacterium glutamicum., Yun Zhang, Xiuling Shang, Shujuan Lai, Yu Zhang, Qitiao Hu, Xin Chai, Bo Wang, Shuwen Liu, Tingyi Wen, 2018
A RecET-assisted CRISPR-Cas9 genome editing in Corynebacterium glutamicum., Bo Wang, Qitiao Hu, Yu Zhang, Ruilin Shi, Xin Chai, Zhe Liu, Xiuling Shang, Yun Zhang, Tingyi Wen, 2018
Native promoters of Corynebacterium glutamicum and its application in l-lysine production., Xiuling Shang, Xin Chai, Xuemei Lu, Yuan Li, Yun Zhang, Guoqiang Wang, Chen Zhang, Shuwen Liu, Yu Zhang, Jiyin Ma, Tingyi Wen, 2018
The KMT1A-GATA3-STAT3 Circuit Is a Novel Self-Renewal Signaling of Human Bladder Cancer Stem Cells., Zhao Yang, Luyun He, Kaisu Lin, Yun Zhang, Aihua Deng, Yong Liang, Chong Li, Tingyi Wen, 2017
A new genome-scale metabolic model of Corynebacterium glutamicum and its application., Yu Zhang, Jingyi Cai, Xiuling Shang, Bo Wang, Shuwen Liu, Xin Chai, Tianwei Tan, Yun Zhang, Tingyi Wen, 2017
A novel pyruvate kinase and its application in lactic acid production under oxygen deprivation in Corynebacterium glutamicum., Shujuan Lai, Xiuling Shang, Yu Zhang, Shuwen Liu, Yong Liang, Yun Zhang, Tingyi Wen, 2016
YjeH Is a Novel Exporter of L-Methionine and Branched-Chain Amino Acids in Escherichia coli., Qian Liu, Yong Liang, Yun Zhang, Xiuling Shang, Shuwen Liu, Jifu Wen, Tingyi Wen, 2015
Assimilation of aromatic compounds by Comamonas testosteroni: characterization and spreadability of protocatechuate 4,5-cleavage pathway in bacteria., Bin Ni, Yun Zhang, DongWei Chen, BaoJun Wang, ShuangJiang Liu, 2013
Characterization and Molecular Mechanism of AroP as an Aromatic Amino Acid and Histidine Transporter in Corynebacterium glutamicum., Xiuling Shang, Yun Zhang, Guoqiang Zhang, Xin Chai, Aihua Deng, Yong Liang, Tingyi Wen, 2013
Development and Application of an Arabinose-Inducible Expression System by Facilitating Inducer Uptake in Corynebacterium glutamicum., Yun Zhang, Xiuling Shang, Aihua Deng, Xin Chai, Shujuan Lai, Guoqiang Zhang, Tingyi Wen, 2012
Metabolic engineering and flux analysis of Corynebacterium glutamicum for L-serine production., Shujuan Lai, Yun Zhang, Shuwen Liu, Yong Liang, Xiuling Shang, Xin Chai, Tingyi Wen, 2012
Genetic and biochemical characterization of Corynebacterium glutamicum ATP phosphoribosyltransferase and its three mutants resistant to feedback inhibition by histidine., Yun Zhang, Xiuling Shang, Aihua Deng, Xin Chai, Shujuan Lai, Guoqiang Zhang, Tingyi Wen, 2012
A Mimicking-of-DNA-Methylation-Patterns Pipeline for Overcoming the Restriction Barrier of Bacteria., Guoqiang Zhang, Wenzhao Wang, Aihua Deng, Zhaopeng Sun, Yun Zhang, Yong Liang, Yongsheng Che, Tingyi Wen, 2012
Enhancing electro-transformation competency of recalcitrant Bacillus amyloliquefaciens by combining cell-wall weakening and cell-membrane fluidity disturbing., Guoqiang Zhang, Peng Bao, Yun Zhang, Aihua Deng, Ning Chen, Tingyi Wen, 2011
Proteomic and molecular investigation on the physiological adaptation of Comamonas sp strain CNB-1 growing on 4-chloronitrobenzene., Yun Zhang, JianFeng Wu, Josef Zeyer, Bo Meng, Lei Liu, ChengYing Jiang, SiQi Liu, ShuangJiang Liu, 2009
The complete genome of Comamonas testosteroni reveals its evolutionary and genetic adaptations to the changing environments., Yun Zhang, 2009
Responses to arsenate stress by Comamonas sp strain CNB-1 at genetic and proteomic levels., YingFei Ma, SuWei Qi, Bo Meng, Muhammad Tausif Chaudhry, SiQi Liu, ShuangJiang Liu, 2007
Comparative proteomes of Corynebacterium glutamicum grown on aromatic compounds revealed novel proteins involved in aromatic degradation and a clear link between aromatic catabolism and gluconeogenesis via fructose-1,6-bisphosphatase., SuWei Qi, Muhammad Tausif Chaudhry, Yun Zhang, Bo Meng, Yan Huang, KX Zhao, Ansgar Poetsch, ChengYing Jiang, Siqi Liu, ShuangJiang Liu, 2007
