Areas of Focus
- Molecular Pharmacology
- Traditional Chinese Medicine Pharmacology
Work Experience
- 2017-12~Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Doctoral Supervisor
- 2014-10~Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher
- 2011-10~2014-10 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Associate Researcher
- 2010-12~Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Master's Supervisor
- 2008-11~2010-07 - M.D. Anderson Cancer Center, USA - Postdoctoral Researcher
- 2005-07~2010-10 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Assistant Researcher
- 2001-07~2005-07 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Research Intern
Academic Background & Achievements
- 2003-09--2008-07 Ph.D. in Science: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- 1996-09--2001-07 Bachelor's in Medicine: Fudan University (formerly Shanghai Medical University)
Publications
- Three new feruloyl glucuronopyranosyl glycerols from Eriocaulon buergerianum with their anti-fibrotic effects on hepatic stellate cells, 11th Author, 2023
- Phosphorylation of PHF2 by AMPK releases the repressive H3K9me2 and inhibits cancer metastasis, 11th Author, 2023
- Phosphoproteomics Reveals the AMPK Substrate Network in Response to DNA Damage and Histone Acetylation, 11th Author, 2022
- Synthesis and Biochemical Evaluation of 8H-Indeno1,2-dthiazole Derivatives as Novel SARS-CoV-2 3CL Protease Inhibitors, 11th Author, 2022
- A Tandemly Activated Fluorescence Probe for Detecting Senescent Cells with Improved Selectivity by Targeting a Biomarker Combination, 11th Author, 2022
- High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors, 1st Author, 2022
- Inner nuclear membrane protein TMEM201 maintains endothelial cell migration and angiogenesis by interacting with the LINC complex, 11th Author, 2022
- Targeting Glutamine Metabolism Ameliorates Autoimmune Hepatitis via Inhibiting T Cell Activation and Differentiation, 11th Author, 2022
- Discovery of highly potent SARS-CoV-2 M-pro inhibitors based on benzoisothiazolone scaffold, 11th Author, 2022
- Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis, 11th Author, 2022
- Bioinspired Design of Reversible Fluorescent Probes for Tracking Nitric Oxide Dynamics in Live Cells, 11th Author, 2021
- Roxithromycin attenuates bleomycin-induced pulmonary fibrosis by targeting senescent cells, 11th Author, 2021
- Guaianolide sesquiterpene lactones from Achillea millefolium L, 5th Author, 2021
- Sleeve gastrectomy ameliorated high-fat diet (HFD)-induced non-alcoholic fatty liver disease and upregulated the nicotinamide adenine dinucleotide+/ Sirtuin-1 pathway in mice, 11th Author, 2021
- Discovery of a Potential Liver Fibrosis Inhibitor from a Mushroom Endophytic Fungus by Genome Mining of a Silent Biosynthetic Gene Cluster, 11th Author, 2021
- AMPK-mediated phosphorylation on 53BP1 promotes c-NHEJ, 11th Author, 2021
- Microenvironment-Responsive Small-Molecule Probe for Pulmonary Fibrosis Detection, 11th Author, 2020
- Pinkment: a synthetic platform for the development of fluorescent probes for diagnostic and theranostic applications, 6th Author, 2020
- The design of a novel near-infrared fluorescent HDAC inhibitor and image of tumor cells, 11th Author, 2020
- Discovery of a 2-pyridinyl urea-containing compound YD57 as a potent inhibitor of apoptosis signal-regulating kinase 1 (ASK1), 5th Author, 2020
- Research Advances of Inner Nuclear Membrane-Associated Degradation, 2nd Author, 2020
- Cyclodextrin-Based Peptide Self-Assemblies (Spds) That Enhance Peptide-Based Fluorescence Imaging and Antimicrobial Efficacy, 4th Author, 2020
- Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis, 0th Author, 2020
- The Role of AMPK in Tumorigenesis and Development, 2nd Author, 2020
- A fluorogenic probe for tracking GSH flux in developing neurons, 11th Author, 2020
- Selective and sensitive fluorescence imaging reveals microenvironment-dependent behavior of NO modulators in the endothelial system, 11th Author, 2020
- Self-Assembled Thin-Layer Glycomaterials With a Proper Shell Thickness for Targeted and Activatable Cell Imaging, 11th Author, 2019
- AMPK regulates anaphase central spindle length by phosphorylation of KIF4A., 11th Author, 2018
- The Roles of Hepatic Macrophages in-Tissue Homeostasis and Liver Diseases, 2nd Author, 2018
- Supramolecular Polymer Dot Ensemble for Ratiometric Detection of Lectins and Targeted Delivery of Imaging Agents, 4th Author, 2017
- Activation and Endocytosis Induced by a 2D Material Agonist., 11th Author, 2017
- An ultrasensitive fluorogenic probe for revealing the role of glutathione in chemotherapy resistance, 11th Author, 2017
- GPCR Activation and Endocytosis Induced by a 2D Material Agonist, 11th Author, 2017
- Photoswitchable arene ruthenium and pentamethylcyclopentadienyl rhodium complexes containing o-sulfonamide azobenzene ligands: synthesis, characterization and cytotoxicity., Not mentioned, 2017
- Remote light-controlled intracellular target recognition by photochromic fluorescent glycoprobes, 4th Author, 2017
- Graphene oxide-enhanced cytoskeleton imaging and mitosis tracking, 11th Author, 2017
- 53bp1与dna双链断裂损伤修复, 2nd Author, 2016
- Foldable glycoprobes capable of fluorogenic crosslinking of biomacromolecules, 3rd Author, 2016
- Targeted Intracellular Production of Reactive Oxygen Species by a 2D Molybdenum Disulfide Glycosheet, 3rd Author, 2016
- Targeted multimodal theranostics via biorecognition controlled aggregation of metallic nanoparticle composites, 2nd Author, 2016
- Development of a novel H2S and GSH detection cocktail for fluorescence imaging, 11th Author, 2016
- Protein Kinase A Rescues Microtubule Affinity-regulating Kinase 2-induced Microtubule Instability and Neurite Disruption by Phosphorylating Serine 409, 11th Author, 2015
- Receptor-targeting fluorescence imaging and theranostics using a graphene oxide based supramolecular glycocomposite, 11th Author, 2015
- Probing disease-related proteins with fluorogenic composite materials, 2nd Author, 2015
- Mixed galactolipid anomers accentuate apoptosis of multiple myeloma cells by inducing DNA damage, 11th Author, 2015
- Glycosylation enhances the aqueous sensitivity and lowers the cytotoxicity of a naphthalimide zinc ion fluorescence probe, 2nd Author, 2015
- Dynamic tracking of pathogenic receptor expression of live cells using pyrenyl glycoanthraquinone-decorated grapheme electrodes., Not mentioned, 2015
- Target-Specific Imaging of Transmembrane Receptors Using Quinonyl Glycosides Functionalized Quantum Dots, Not mentioned
