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Yohei Niikura
Medical School
Nanjing University
Jiangsu
Language: Japanese, English, Chinese
Mitosis
Cell Cycle
Chromosomal Instability
Epigenetics
Tumor Cells
Brain Cells
Molecular Mechanisms
Cenp-A
Ubiquitylation
Cell Viability
Areas of Focus
- Molecular mechanisms of mitosis, cell cycle, chromosomal instability, and epigenetics in tumor and brain cells
Work Experience
- 2008-2010 - St. Jude Children's Research Hospital - Researcher
- 2010-2016 - National Children's Hospital Research Institute, USA - Researcher
- 2016-2018 - Greehey Children's Cancer Research Institute, Texas State University, USA - Researcher
- 2018-present - Nanjing University Model Animal Research Institute - Principal Investigator
Academic Background & Achievements
- 2000 - PhD: University of Florence, Italy
- Postdoctoral training at Friedrich Miescher Institute, Switzerland
- Postdoctoral training at National Center for Geriatrics and Gerontology, Japan
- Postdoctoral training at St. Jude Children's Research Hospital, USA
Publications
- Mass Spectrometry Analysis to Identify Ubiquitylation of EYFP-tagged CENP-A (EYFP-CENP-A), Niikura Y, Fang L, Kitagawa R, Li P, Xi Y, You J, Gao Y, Kitagawa K, 2020
- CENP-A Ubiquitylation Is Indispensable to Cell Viability, Niikura Y, Kitagawa R, Fang L, Kitagawa K, 2019
- CENP-A Ubiquitylation Contributes to Maintaining the Chromosomal Location of the Centromere, Niikura Y, Kitagawa R, Kitagawa K, 2019
- The position of the centromere is marked with ubiquitylation of CENP-A, Niikura Y, Kitagawa R, Ogi H, Kitagawa K, 2018
- SGT1-HSP90 complex is required for CENP-A deposition at centromeres, Niikura Y, Kitagawa R, Kitagawa K, 2017
- CENP-A Ubiquitylation Is Required for CENP-A Deposition at the Centromere, Niikura Y, Kitagawa R, Kitagawa K, 2017
Awards
- FASEB Young Investigator Award (2009): FASEB Mitosis Conference in Tuscany, Italy
