Professor | Qing Zhang | Asia Growth Partners

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Name	Qing Zhang
Contact Information	zhangqing@nicemice.cn
Language ability	English, Chinese
Province	Jiangsu

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Name

Qing Zhang

Contact Information

zhangqing@nicemice.cn

Language ability

English, Chinese

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing University
Faculty	Medical School
Academic Background & Achievements	2002 - PhD in Science: Fudan University 2003-2009 - Postdoctoral Research in Developmental Biology: UT Southwestern Medical Center at Dallas
Work Experience	2003-2009 - UT Southwestern Medical Center at Dallas - Postdoctoral Researcher 2009-Present - Nanjing University Model Animal Research Institute - Professor and Doctoral Supervisor

University/Lab Affiliation and Title

Nanjing University

Faculty

Medical School

Academic Background & Achievements

2002 - PhD in Science: Fudan University
2003-2009 - Postdoctoral Research in Developmental Biology: UT Southwestern Medical Center at Dallas

Work Experience

2003-2009 - UT Southwestern Medical Center at Dallas - Postdoctoral Researcher
2009-Present - Nanjing University Model Animal Research Institute - Professor and Doctoral Supervisor

Areas of Focus	Regulation of Hedgehog Signal Transduction Mechanisms of Mitochondrial Diseases Mechanisms of Lysosomal Diseases
Publications	Regulation of Hedgehog Signal Transduction by Ubiquitination and Deubiquitination, Zhang Q, Jiang J., 2021 E3 ligase Herc4 regulates Hedgehog signalling through promoting Smoothened degradation, Jiang W, Yao X, Shan Z, Li W, Gao Y, Zhang Q., 2019 The deubiquitinase UCHL5/UCH37 positively regulates Hedgehog signaling by deubiquitinating Smoothened, Zhou Z, Yao X, Pang S, Chen P, Jiang W, Shan Z, Zhang Q., 2018 Capping Enzyme mRNA-cap/RNGTT Regulates Hedgehog Pathway Activity by Antagonizing Protein Kinase A, Chen P, Zhou Z, Yao X, Pang S, Liu M, Jiang W, Jiang J, Zhang Q., 2017 Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling, Zhou Z, Yao X, Li S, Xiong Y, Dong X, Zhao Y, Jiang J, Zhang Q., 2015 Truncated ERG Oncoproteins from TMPRSS2-ERG Fusions Are Resistant to SPOP-Mediated Proteasome Degradation, An J, Ren S, Murphy S, Dalangood S, Chang C, Pang X, Cui Y, Wang L, Pan Y, Zhang X, Zhu Y, Wang C, Halling G, Cheng L, Sukov W, Karnes R, Vasmatzis G, Zhang Q, Zhang J, Cheville J, Yan J, Sun Y, Huang H., 2015 Hedgehog signaling downregulates Suppressor of Fused through the HIB/SPOP-Crn axis in Drosophila, Liu C, Zhou Z, Chen P, Su MY, Chang CJ, Yan J, Jiang J, Zhang Q., 2014 Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase, Zhang Q, Shi Q, Chen Y, Yue T, Li S, Wang B, Jiang J., 2009 The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control, Zhang L, Ren F, Zhang Q, Chen Y, Wang B, Jiang J., 2008 A Hedgehog-induced BTB protein modulates Hedgehog signaling responses by degrading Ci/Gli transcription factor, Zhang Q, Zhang L, Wang B, Ou CY, Chien CT, Jiang J., 2006 Phosphorylation of Cubitus interruptus by Double-time/CKIe and CKIa targets it for Slimb/b-TRCP mediated proteolytic processing, Jia J, Zhang L, Zhang Q, Tong C, Wang B, Hou F, Amanai K, Jiang J., 2005

Areas of Focus

Regulation of Hedgehog Signal Transduction
Mechanisms of Mitochondrial Diseases
Mechanisms of Lysosomal Diseases

Publications

Regulation of Hedgehog Signal Transduction by Ubiquitination and Deubiquitination, Zhang Q, Jiang J., 2021
E3 ligase Herc4 regulates Hedgehog signalling through promoting Smoothened degradation, Jiang W, Yao X, Shan Z, Li W, Gao Y, Zhang Q., 2019
The deubiquitinase UCHL5/UCH37 positively regulates Hedgehog signaling by deubiquitinating Smoothened, Zhou Z, Yao X, Pang S, Chen P, Jiang W, Shan Z, Zhang Q., 2018
Capping Enzyme mRNA-cap/RNGTT Regulates Hedgehog Pathway Activity by Antagonizing Protein Kinase A, Chen P, Zhou Z, Yao X, Pang S, Liu M, Jiang W, Jiang J, Zhang Q., 2017
Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling, Zhou Z, Yao X, Li S, Xiong Y, Dong X, Zhao Y, Jiang J, Zhang Q., 2015
Truncated ERG Oncoproteins from TMPRSS2-ERG Fusions Are Resistant to SPOP-Mediated Proteasome Degradation, An J, Ren S, Murphy S, Dalangood S, Chang C, Pang X, Cui Y, Wang L, Pan Y, Zhang X, Zhu Y, Wang C, Halling G, Cheng L, Sukov W, Karnes R, Vasmatzis G, Zhang Q, Zhang J, Cheville J, Yan J, Sun Y, Huang H., 2015
Hedgehog signaling downregulates Suppressor of Fused through the HIB/SPOP-Crn axis in Drosophila, Liu C, Zhou Z, Chen P, Su MY, Chang CJ, Yan J, Jiang J, Zhang Q., 2014
Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase, Zhang Q, Shi Q, Chen Y, Yue T, Li S, Wang B, Jiang J., 2009
The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control, Zhang L, Ren F, Zhang Q, Chen Y, Wang B, Jiang J., 2008
A Hedgehog-induced BTB protein modulates Hedgehog signaling responses by degrading Ci/Gli transcription factor, Zhang Q, Zhang L, Wang B, Ou CY, Chien CT, Jiang J., 2006
Phosphorylation of Cubitus interruptus by Double-time/CKIe and CKIa targets it for Slimb/b-TRCP mediated proteolytic processing, Jia J, Zhang L, Zhang Q, Tong C, Wang B, Hou F, Amanai K, Jiang J., 2005

Hedgehog Signal Transduction Ubiquitination Deubiquitination Mitochondrial Lysosomal Genetics Biochemistry Molecular Biology Drosophila

Jin Tang Dong - Southern University of Science and Technology

Ning Jia - Southern University of Science and Technology

Ji Yang - Southern University of Science and Technology

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