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Qing Zhang
Medical School
Nanjing University
Jiangsu
Language: English, Chinese
Hedgehog
Signal Transduction
Ubiquitination
Deubiquitination
Mitochondrial
Lysosomal
Genetics
Biochemistry
Molecular Biology
Drosophila
Areas of Focus
- Regulation of Hedgehog Signal Transduction
- Mechanisms of Mitochondrial Diseases
- Mechanisms of Lysosomal Diseases
Work Experience
- 2003-2009 - UT Southwestern Medical Center at Dallas - Postdoctoral Researcher
- 2009-Present - Nanjing University Model Animal Research Institute - Professor and Doctoral Supervisor
Academic Background & Achievements
- 2002 - PhD in Science: Fudan University
- 2003-2009 - Postdoctoral Research in Developmental Biology: UT Southwestern Medical Center at Dallas
Publications
- Regulation of Hedgehog Signal Transduction by Ubiquitination and Deubiquitination, Zhang Q, Jiang J., 2021
- E3 ligase Herc4 regulates Hedgehog signalling through promoting Smoothened degradation, Jiang W, Yao X, Shan Z, Li W, Gao Y, Zhang Q., 2019
- The deubiquitinase UCHL5/UCH37 positively regulates Hedgehog signaling by deubiquitinating Smoothened, Zhou Z, Yao X, Pang S, Chen P, Jiang W, Shan Z, Zhang Q., 2018
- Capping Enzyme mRNA-cap/RNGTT Regulates Hedgehog Pathway Activity by Antagonizing Protein Kinase A, Chen P, Zhou Z, Yao X, Pang S, Liu M, Jiang W, Jiang J, Zhang Q., 2017
- Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling, Zhou Z, Yao X, Li S, Xiong Y, Dong X, Zhao Y, Jiang J, Zhang Q., 2015
- Truncated ERG Oncoproteins from TMPRSS2-ERG Fusions Are Resistant to SPOP-Mediated Proteasome Degradation, An J, Ren S, Murphy S, Dalangood S, Chang C, Pang X, Cui Y, Wang L, Pan Y, Zhang X, Zhu Y, Wang C, Halling G, Cheng L, Sukov W, Karnes R, Vasmatzis G, Zhang Q, Zhang J, Cheville J, Yan J, Sun Y, Huang H., 2015
- Hedgehog signaling downregulates Suppressor of Fused through the HIB/SPOP-Crn axis in Drosophila, Liu C, Zhou Z, Chen P, Su MY, Chang CJ, Yan J, Jiang J, Zhang Q., 2014
- Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase, Zhang Q, Shi Q, Chen Y, Yue T, Li S, Wang B, Jiang J., 2009
- The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control, Zhang L, Ren F, Zhang Q, Chen Y, Wang B, Jiang J., 2008
- A Hedgehog-induced BTB protein modulates Hedgehog signaling responses by degrading Ci/Gli transcription factor, Zhang Q, Zhang L, Wang B, Ou CY, Chien CT, Jiang J., 2006
- Phosphorylation of Cubitus interruptus by Double-time/CKIe and CKIa targets it for Slimb/b-TRCP mediated proteolytic processing, Jia J, Zhang L, Zhang Q, Tong C, Wang B, Hou F, Amanai K, Jiang J., 2005
