Professor | 张青 | 数字化转型顾问

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Name	张青
Contact Information	zhangqing@nicemice.cn
Language ability	英语, 中文
Province	江苏

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Name

张青

Contact Information

zhangqing@nicemice.cn

Language ability

英语, 中文

Province

江苏

University/Lab Affiliation and Title	南京大学
Faculty	Medical School
Academic Background & Achievements	2002 - 理学博士: 复旦大学 2003-2009 - 发育生物学博士后研究: 美国德克萨斯大学西南医学中心
Work Experience	2003-2009 - 美国德克萨斯大学西南医学中心 - 博士后研究员 2009-至今 - 南京大学模式动物研究所 - 教授和博士生导师

University/Lab Affiliation and Title

南京大学

Faculty

Medical School

Academic Background & Achievements

2002 - 理学博士: 复旦大学
2003-2009 - 发育生物学博士后研究: 美国德克萨斯大学西南医学中心

Work Experience

2003-2009 - 美国德克萨斯大学西南医学中心 - 博士后研究员
2009-至今 - 南京大学模式动物研究所 - 教授和博士生导师

Areas of Focus	Hedgehog信号转导调节研究线粒体疾病机制研究溶酶体疾病机制研究
Publications	Regulation of Hedgehog Signal Transduction by Ubiquitination and Deubiquitination, Zhang Q, Jiang J., 2021 E3 ligase Herc4 regulates Hedgehog signalling through promoting Smoothened degradation, Jiang W, Yao X, Shan Z, Li W, Gao Y, Zhang Q., 2019 The deubiquitinase UCHL5/UCH37 positively regulates Hedgehog signaling by deubiquitinating Smoothened, Zhou Z, Yao X, Pang S, Chen P, Jiang W, Shan Z, Zhang Q., 2018 Capping Enzyme mRNA-cap/RNGTT Regulates Hedgehog Pathway Activity by Antagonizing Protein Kinase A, Chen P, Zhou Z, Yao X, Pang S, Liu M, Jiang W, Jiang J, Zhang Q., 2017 Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling, Zhou Z, Yao X, Li S, Xiong Y, Dong X, Zhao Y, Jiang J, Zhang Q., 2015 Truncated ERG Oncoproteins from TMPRSS2-ERG Fusions Are Resistant to SPOP-Mediated Proteasome Degradation, An J, Ren S, Murphy S, Dalangood S, Chang C, Pang X, Cui Y, Wang L, Pan Y, Zhang X, Zhu Y, Wang C, Halling G, Cheng L, Sukov W, Karnes R, Vasmatzis G, Zhang Q, Zhang J, Cheville J, Yan J, Sun Y, Huang H., 2015 Hedgehog signaling downregulates Suppressor of Fused through the HIB/SPOP-Crn axis in Drosophila, Liu C, Zhou Z, Chen P, Su MY, Chang CJ, Yan J, Jiang J, Zhang Q., 2014 Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase, Zhang Q, Shi Q, Chen Y, Yue T, Li S, Wang B, Jiang J., 2009 The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control, Zhang L, Ren F, Zhang Q, Chen Y, Wang B, Jiang J., 2008 A Hedgehog-induced BTB protein modulates Hedgehog signaling responses by degrading Ci/Gli transcription factor, Zhang Q, Zhang L, Wang B, Ou CY, Chien CT, Jiang J., 2006 Phosphorylation of Cubitus interruptus by Double-time/CKIe and CKIa targets it for Slimb/b-TRCP mediated proteolytic processing, Jia J, Zhang L, Zhang Q, Tong C, Wang B, Hou F, Amanai K, Jiang J., 2005

Areas of Focus

Hedgehog信号转导调节研究
线粒体疾病机制研究
溶酶体疾病机制研究

Publications

Regulation of Hedgehog Signal Transduction by Ubiquitination and Deubiquitination, Zhang Q, Jiang J., 2021
E3 ligase Herc4 regulates Hedgehog signalling through promoting Smoothened degradation, Jiang W, Yao X, Shan Z, Li W, Gao Y, Zhang Q., 2019
The deubiquitinase UCHL5/UCH37 positively regulates Hedgehog signaling by deubiquitinating Smoothened, Zhou Z, Yao X, Pang S, Chen P, Jiang W, Shan Z, Zhang Q., 2018
Capping Enzyme mRNA-cap/RNGTT Regulates Hedgehog Pathway Activity by Antagonizing Protein Kinase A, Chen P, Zhou Z, Yao X, Pang S, Liu M, Jiang W, Jiang J, Zhang Q., 2017
Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling, Zhou Z, Yao X, Li S, Xiong Y, Dong X, Zhao Y, Jiang J, Zhang Q., 2015
Truncated ERG Oncoproteins from TMPRSS2-ERG Fusions Are Resistant to SPOP-Mediated Proteasome Degradation, An J, Ren S, Murphy S, Dalangood S, Chang C, Pang X, Cui Y, Wang L, Pan Y, Zhang X, Zhu Y, Wang C, Halling G, Cheng L, Sukov W, Karnes R, Vasmatzis G, Zhang Q, Zhang J, Cheville J, Yan J, Sun Y, Huang H., 2015
Hedgehog signaling downregulates Suppressor of Fused through the HIB/SPOP-Crn axis in Drosophila, Liu C, Zhou Z, Chen P, Su MY, Chang CJ, Yan J, Jiang J, Zhang Q., 2014
Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase, Zhang Q, Shi Q, Chen Y, Yue T, Li S, Wang B, Jiang J., 2009
The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control, Zhang L, Ren F, Zhang Q, Chen Y, Wang B, Jiang J., 2008
A Hedgehog-induced BTB protein modulates Hedgehog signaling responses by degrading Ci/Gli transcription factor, Zhang Q, Zhang L, Wang B, Ou CY, Chien CT, Jiang J., 2006
Phosphorylation of Cubitus interruptus by Double-time/CKIe and CKIa targets it for Slimb/b-TRCP mediated proteolytic processing, Jia J, Zhang L, Zhang Q, Tong C, Wang B, Hou F, Amanai K, Jiang J., 2005

Hedgehog 信号转导泛素化去泛素化线粒体溶酶体遗传学生物化学分子生物学果蝇

龚克 - 武汉大学

丁健 - 中国科学院大学

侯法建 - 中国科学院大学

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