Professor | Xiaoming Ding | Asia Growth Partners

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Name	Xiaoming Ding
Contact Information	xmding74@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Xiaoming Ding

Contact Information

xmding74@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Life Sciences
Academic Background & Achievements	1996 - Bachelor's Degree: Wuhan University, School of Life Sciences 2001 - Doctorate: Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences
Work Experience	2002-2003 - Postdoctoral Research: Queen's Medical Centre, University of Nottingham 2003-2005 - Postdoctoral Research: Institute of Medical Sciences, University of Aberdeen 2005-present - Lecturer, Associate Professor: School of Life Sciences, Fudan University

University/Lab Affiliation and Title

Fudan University

Faculty

Life Sciences

Academic Background & Achievements

1996 - Bachelor's Degree: Wuhan University, School of Life Sciences
2001 - Doctorate: Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences

Work Experience

2002-2003 - Postdoctoral Research: Queen's Medical Centre, University of Nottingham
2003-2005 - Postdoctoral Research: Institute of Medical Sciences, University of Aberdeen
2005-present - Lecturer, Associate Professor: School of Life Sciences, Fudan University

Areas of Focus	Microbial Molecular Genetics and Metabolic Regulation Synthetic Biology
Publications	Heterologous redox partners supporting the efficient catalysis of epothilone B biosynthesis by EpoK in Schlegelella brevitalea, Liang J, Wang H, Bian X, Zhang Y, Zhao G, Ding X, 2020 Reassembly of the Biosynthetic Gene Cluster Enables High Epothilone Yield in Engineered Schlegelella brevitalea, Yu Y, Wang H, Tang B, Liang J, Zhang L, Wang H, Bian X, Li YZ, Zhang Y, Zhao GP, Ding X, 2020 Reclassification of 'Polyangium brachysporum' DSM 7029 as Schlegelella brevitalea sp. nov., Tang B, Yu Y, Liang J, Zhang Y, Bian X, Zhi X, Ding X, 2019 Efficient circular gene knockout system for Burkholderiales strain DSM 7029 and Mycobacterium smegmatis mc2 155, Lei X, Fan Q, Huang T, Liu H, Zhao G, Ding X, 2019 Site-specificity of serine integrase demonstrated by the attB sequence preference of phiBT1 integrase, Lei X, Wang L, Zhao G, Ding X, 2018 Identification of the streptothricin and tunicamycin biosynthetic gene clusters by genome mining in Streptomyces sp. strain fd1-xmd, Yu Y, Tang B, Dai R, Zhang B, Chen L, Yang H, Zhao G, Ding X, 2018 Morphology engineering of Streptomyces coelicolor M145 by sub-inhibitory concentrations of antibiotics, Wang H, Zhao G, Ding X, 2017 Heterologous Production and Yield Improvement of Epothilones in Burkholderiales Strain DSM 7029, Bian X, Tang B, Yu Y, Tu Q, Gross F, Wang H, Li A, Fu J, Shen Y, Li YZ, Stewart AF, Zhao G, Ding X, Müller R, Zhang Y, 2017 RifZ (AMED_0655) Is a Pathway-Specific Regulator for Rifamycin Biosynthesis in Amycolatopsis mediterranei, Li C, Liu X, Lei C, Yan H, Shao Z, Wang Y, Zhao G, Wang J, Ding X, 2017 Bxb1 integrase serves as a highly efficient DNA recombinase in rapid metabolite pathway assembly, Wang X, Tang B, Ye Y, Mao Y, Lei X, Zhao G, Ding X, 2017 Streptomyces yangpuensis sp. nov., isolated from soil, Tang B, Yu Y, Zhi X, Yang L, Cen X, Zhao G, Ding X, 2016 Complete genome sequence of the glidobactin producing strain [Polyangium] brachysporum DSM 7029, Tang B, Yu Y, Zhang Y, Zhao G, Ding X, 2015 NGSmirPlant: comprehensive characterization of the small RNA transcriptomes of plants, Bai J, Dan C, Zhang Y, Zhao G, Ding X, 2015 Control of directionality in Streptomyces phage φBT1 integrase-mediated site-specific recombination, Zhang L, Zhu B, Dai R, Zhao G, Ding X, 2013 An efficient procedure for marker-free mutagenesis of S. coelicolor by site-specific recombination for secondary metabolite overproduction, Zhang B, Zhang L, Dai R, Yu M, Zhao G, Ding X, 2013 Tandem assembly of the epothilone biosynthetic gene cluster by in vitro site-specific recombination, Zhang L, Zhao G, Ding X, 2011 DNA cleavage is independent of synapsis during Streptomyces phage phiBT1 integrase-mediated site-specific recombination, Zhang L, Wang L, Wang J, Ou X, Zhao G, Ding X, 2010 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism, Zhao W, Zhong Y, Yuan H, Wang J, Zheng H, Wang Y, Cen X, Xu F, Bai J, Han X, Lu G, Zhu Y, Shao Z, Yan H, Li C, Peng N, Zhang Z, Zhang Y, Lin W, Fan Y, Qin Z, Hu Y, Zhu B, Wang S, Ding X, Zhao G, 2010 Characterization of rrdA, a TetR Family Protein Gene Involved in the Regulation of Secondary Metabolism in Streptomyces coelicolor, Ou X, Zhang B, Zhang L, Zhao G, Ding X, 2009 Highly Efficient In Vitro Site-Specific Recombination System Based on Streptomyces Phage BT1 Integrase, Zhang L, Ou X, Zhao G, Ding X, 2008

Areas of Focus

Microbial Molecular Genetics and Metabolic Regulation
Synthetic Biology

Publications

Heterologous redox partners supporting the efficient catalysis of epothilone B biosynthesis by EpoK in Schlegelella brevitalea, Liang J, Wang H, Bian X, Zhang Y, Zhao G, Ding X*, 2020
Reassembly of the Biosynthetic Gene Cluster Enables High Epothilone Yield in Engineered Schlegelella brevitalea, Yu Y, Wang H, Tang B, Liang J, Zhang L, Wang H, Bian X, Li YZ, Zhang Y, Zhao GP*, Ding X*, 2020
Reclassification of 'Polyangium brachysporum' DSM 7029 as Schlegelella brevitalea sp. nov., Tang B, Yu Y, Liang J, Zhang Y, Bian X, Zhi X*, Ding X*, 2019
Efficient circular gene knockout system for Burkholderiales strain DSM 7029 and Mycobacterium smegmatis mc2 155, Lei X, Fan Q, Huang T, Liu H, Zhao G, Ding X*, 2019
Site-specificity of serine integrase demonstrated by the attB sequence preference of phiBT1 integrase, Lei X, Wang L, Zhao G, Ding X*, 2018
Identification of the streptothricin and tunicamycin biosynthetic gene clusters by genome mining in Streptomyces sp. strain fd1-xmd, Yu Y, Tang B, Dai R, Zhang B, Chen L, Yang H, Zhao G*, Ding X*, 2018
Morphology engineering of Streptomyces coelicolor M145 by sub-inhibitory concentrations of antibiotics, Wang H, Zhao G*, Ding X*, 2017
Heterologous Production and Yield Improvement of Epothilones in Burkholderiales Strain DSM 7029, Bian X, Tang B, Yu Y, Tu Q, Gross F, Wang H, Li A, Fu J, Shen Y, Li YZ, Stewart AF, Zhao G, Ding X*, Müller R*, Zhang Y*, 2017
RifZ (AMED_0655) Is a Pathway-Specific Regulator for Rifamycin Biosynthesis in Amycolatopsis mediterranei, Li C, Liu X, Lei C, Yan H, Shao Z, Wang Y, Zhao G, Wang J*, Ding X*, 2017
Bxb1 integrase serves as a highly efficient DNA recombinase in rapid metabolite pathway assembly, Wang X, Tang B, Ye Y, Mao Y, Lei X, Zhao G*, Ding X*, 2017
Streptomyces yangpuensis sp. nov., isolated from soil, Tang B, Yu Y, Zhi X, Yang L, Cen X, Zhao G*, Ding X*, 2016
Complete genome sequence of the glidobactin producing strain [Polyangium] brachysporum DSM 7029, Tang B, Yu Y, Zhang Y*, Zhao G*, Ding X*, 2015
NGSmirPlant: comprehensive characterization of the small RNA transcriptomes of plants, Bai J, Dan C, Zhang Y, Zhao G*, Ding X*, 2015
Control of directionality in Streptomyces phage φBT1 integrase-mediated site-specific recombination, Zhang L, Zhu B, Dai R, Zhao G*, Ding X*, 2013
An efficient procedure for marker-free mutagenesis of S. coelicolor by site-specific recombination for secondary metabolite overproduction, Zhang B, Zhang L, Dai R, Yu M, Zhao G*, Ding X*, 2013
Tandem assembly of the epothilone biosynthetic gene cluster by in vitro site-specific recombination, Zhang L, Zhao G*, Ding X*, 2011
DNA cleavage is independent of synapsis during Streptomyces phage phiBT1 integrase-mediated site-specific recombination, Zhang L, Wang L, Wang J, Ou X, Zhao G*, Ding X*, 2010
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism, Zhao W, Zhong Y, Yuan H, Wang J, Zheng H, Wang Y, Cen X, Xu F, Bai J, Han X, Lu G, Zhu Y, Shao Z, Yan H, Li C, Peng N, Zhang Z, Zhang Y, Lin W, Fan Y, Qin Z, Hu Y, Zhu B, Wang S*, Ding X*, Zhao G*, 2010
Characterization of rrdA, a TetR Family Protein Gene Involved in the Regulation of Secondary Metabolism in Streptomyces coelicolor, Ou X, Zhang B, Zhang L, Zhao G*, Ding X*, 2009
Highly Efficient In Vitro Site-Specific Recombination System Based on Streptomyces Phage BT1 Integrase, Zhang L, Ou X, Zhao G*, Ding X*, 2008

Microbial Genetics Metabolic Regulation Synthetic Biology Epothilone Biosynthesis Gene Clusters Streptomyces Burkholderiales Dna Recombination Genome Mining Secondary Metabolites

Yinhua Lu - Shanghai Normal University

Yinhua Lu - Shanghai Normal University

Wenfang Wang - Shanghai Normal University

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