Areas of Focus
- Bioinformatics methods development
- High-throughput multi-omics data modeling
- Analysis and mining of disease and developmental alternative splicing
- RNA therapeutic approaches for splicing-related diseases
Work Experience
- 2016-2021 - Postdoctoral Researcher - Columbia University, Department of Systems Biology
- 2022-Present - Junior Researcher and PI - Fudan University, School of Life Sciences
Academic Background & Achievements
- 2011 - Bachelor's Degree in Bioinformatics: Huazhong University of Science and Technology
- 2016 - Ph.D. in Bioinformatics: Tsinghua University
Publications
- Complexity and graded regulation of neuronal cell type-specific alternative splicing revealed by single-cell RNA sequencing, Feng H, Moakley DF, Chen S, McKenzie MG, Menon V, Zhang C, 2021
- Modeling the in vivo specificity of RNA-binding proteins by precisely registering protein-RNA crosslink sites, Feng H, Bao S, Weyn-Vanhentenryck SM, Khan A, Wong J, Shah A, Flynn ED, Zhang C, 2019
- Precise temporal regulation of alternative splicing during neural development, Weyn-Vanhentenryck SM, Feng H, Ustianenko D, Duffie R, Yan Q, Jacko M, Martinez JC, Goodwin M, Zhang X, Hengst U, Lomvardas S, Swanson MS, Zhang C, 2018
- Characterization of kinase gene expression and splicing profile in prostate cancer with RNA-Seq data, Feng H, Li T, Zhang X, 2018
- mRIN for direct assessment of genome-wide and gene-specific mRNA integrity from large-scale RNA-sequencing data, Feng H, Zhang X, Zhang C, 2015
- Opportunities and methods for studying alternative splicing in cancer with RNA-Seq, Feng H, Qin Z, Zhang X, 2013
- Rbfox Splicing Factors Promote Neuronal Maturation and Axon Initial Segment Assembly, Jacko M, Weyn-Vanhentenryck SM, Smerdon JW, Yan R, Feng H, Williams DJ, Pai J, Xu K, Wichterle H, Zhang C, 2018
- Vascular-derived SPARC and SerpinE1 regulate interneuron tangential migration and accelerate functional maturation of human stem cell-derived interneurons, Genestine M, Ambriz D, Crabtree GW, Dummer P, Molotkova A, Quintero M, Mela A, Biswas S, Feng H, Zhang C, Canoll P, Hargus G, Agalliu D, Gogos JA, Au E, 2021
- Alternative splicing at neuroligin site A regulates glycan interaction and synaptogenic activity, Oku S, Feng H, Connor S, Toledo A, Zhang P, Zhang Y, Thoumine O, Zhang C, Craig AM, 2020
